Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-25Clinical Trial Update: Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) [Phase 3]
Phase 3 trial updating sickle cell disease with a focus on cardiovascular risk through red cell exchange therapy (SCD-CARRE).
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EMA withdrawal · 2026-08-21EMA Suspended: Oxbryta (voxelotor) — Pfizer Europe MA EEIG
The EMA suspended Oxbryta (voxelotor) for treating sickle cell disease-related anemia.
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CLINICAL_TRIALS trial_result · 2026-08-04Clinical Trial Results: Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease [NA]
Clinical trial results evaluating the effectiveness of a computerized tool (PAINRelieveIt) to help manage pain in sickle cell disease; resul…
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CLINICAL_TRIALS trial_result · 2026-07-28Clinical Trial Results: Hyperbaric Oxygen Therapy in Sickle Cell Pain [NA]
Clinical trial results evaluate hyperbaric oxygen therapy for vaso-occlusive crisis in sickle cell disease; results have been posted after c…
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CLINICAL_TRIALS trial_result · 2026-06-30Clinical Trial Results: Gerofit Exercise Intervention for Older Adults With Sickle Cell Disease (SICKLE-FIT Study) [NA]
Results from the Gerofit exercise intervention trial in older adults with sickle cell disease have been completed and posted.
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CLINICAL_TRIALS trial_result · 2026-06-10Clinical Trial Results: A Study to Learn About Sickle Cell Disease In Adult Patients
Clinical trial results for a study on sickle cell disease in adults completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-03Clinical Trial Update: Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) [Phase 3]
Phase 3 clinical trial update for the SCD-CARRE study investigating red cell exchange to address cardiovascular risk in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Results: Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507) [Phase 2]
Phase 2 trial evaluating haploidentical bone marrow transplantation in patients with sickle cell disease.
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EMA approval · 2026-04-28EMA Authorised: Xromi (hydroxycarbamide) — Lipomed GmbH
Xromi (hydroxycarbamide) has been authorised in the EU for use in anemia and sickle cell disease.
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EMA approval · 2026-04-28EMA Authorised: Siklos (hydroxycarbamide) — Theravia
Authorization of Siklos (hydroxycarbamide) in the European market for anemia and sickle cell indications.
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Results: Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies [NA]
Pilot study results for peripheral blood stem cell transplantation with TCRab depletion in hemoglobinopathies were completed and results pos…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat [Phase 1, Phase 2]
An ongoing extension study evaluating long-term safety, tolerability, pharmacokinetics, and pharmacodynamics of mitapivat in adults with sta…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease [Phase 2]
Phase 2 pediatric pharmacokinetics and safety study of etavopivat in sickle cell disease; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease [Phase 3]
Phase 3 clinical trial evaluating etavopivat for sickle cell disease is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: School Readiness Intervention for Preschool Children With Sickle Cell Disease [NA]
A clinical trial at St. Jude Children's Research Hospital is recruiting preschool children with Sickle Cell Disease to evaluate a school rea…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease
This clinical trial update describes investigations into the mechanistic effects of mitapivat in subjects with sickle cell disease, which is…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
A clinical trial update describes development of non-invasive prenatal diagnosis for single-gene disorders. The study, based in Paris, is cu…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD) [Phase 2]
This clinical trial update describes a Phase 2 dose-finding study to evaluate the efficacy and safety of tebapivat in participants with sick…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease [Phase 1]
This is a Phase 1 clinical trial evaluating methylphenidate for attention and executive function deficits in children with sickle cell disea…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Transcranial Photobiomodulation Treatment in Patients With Sickle Cell Disease [NA]
An update on a clinical trial evaluating transcranial photobiomodulation for sickle cell disease, sponsored by St. Jude Children's Research …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP) [Phase 2, Phase 3]
This document provides a clinical trial update on the Phase 2/Phase 3 study evaluating Mitapivat (AG-348) in participants with Sickle Cell D…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Autologous Testicular Tissue Transplantation [NA]
Recruitment is ongoing for an autologous testicular tissue transplantation trial addressing cancer and hematologic diseases, including sickl…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Exploring Adherence Monitoring in Sickle Cell Disease
Clinical trial update on adherence monitoring in sickle cell disease; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA) [NA]
Clinical trial EMPOWER-AYA aims to involve adolescents and young adults with sickle cell disease in treatment decisions and shared decision-…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies
An observational study to deeply phenotype major organs in people with sickle cell disease after curative therapies, aiming to characterize …