Shigellosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-08-11Clinical Trial Update: Safety Study of Inactivated Shigella Whole Cell Vaccine in Adults [Phase 1]
Phase 1 safety study of an inactivated Shigella whole cell vaccine completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Phase 2b Challenge Study With the Bioconjugate Vaccine Flexyn2a [Phase 2]
Phase 2b trial of the bioconjugate vaccine Flexyn2a for Shigellosis completed; results posted in 2021.
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FDA approval · 2020-07-28FDA Approved: BACTRIM — Supplemental Application (Sun Pharmaceutical Industries, Inc)
FDA approved a supplemental application for BACTRIM (sulfamethoxazole and trimethoprim) filed by Sun Pharmaceutical Industries, Inc. to upda…
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CLINICAL_TRIALS trial_result · 2020-07-22Clinical Trial Update: Safety and Immunogenicity of Artificial Invaplex (Shigella Flexneri 2a InvaplexAR) [Phase 1]
Phase 1 clinical trial assessing safety and immunogenicity of artificial Invaplex for Shigella flexneri 2a; results posted after completion.
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CLINICAL_TRIALS trial_result · 2019-02-18Clinical Trial Update: A Study of the Safety and Immune Response of 2 Doses of a New Shigella Vaccine in Kenyan Adults [Phase 2]
Phase 2 trial evaluating the safety and immune response of two-dose Shigella vaccine in Kenyan adults. The study is completed with results p…
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CLINICAL_TRIALS research · 2019-01-29Clinical Trial Update: Multidrug Resistant Shigella Infection in Bangladesh
An update on a clinical trial in Bangladesh studying treatments for multidrug-resistant Shigella infection. The current trial status is unkn…
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: Safety and Immunogenicity of Two Live, Attenuated Oral Shigella Sonnei Vaccines: WRSs2 and WRSs3 [Phase 1]
A Phase 1 trial evaluating safety and immunogenicity of two live, attenuated oral Shigella Sonnei vaccines, WRSs2 and WRSs3.
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: A Phase 1, Dose Escalation Study, to Evaluate a New Shigella Sonnei Vaccine in Healthy Adults. [Phase 1]
Phase 1 dose-escalation study of a Shigella sonnei vaccine in healthy adults has completed and results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-11-13Clinical Trial Update: Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate [Phase 1, Phase 2]
Clinical trials for WRSS1, a Shigella sonnei vaccine candidate, completed Phase 1/2 to assess safety and efficacy for dysentery caused by Sh…
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: SF2a-TT15 Conjugate Vaccine in Healthy Adult Volunteers [Phase 1]
Phase 1 clinical trial update shows completion of a Phase 1 study of the SF2a-TT15 Conjugate Vaccine in healthy adult volunteers. The study …
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CLINICAL_TRIALS withdrawal · 2017-11-20Clinical Trial Update: Safety, Immunogenicity and Efficacy Study of Inactivated Whole Cell Shigella Flexneri 2a Vaccine With and Without dmLT in Adults [Phase 2]
A Phase 2 safety, immunogenicity and efficacy trial evaluating an inactivated whole-cell Shigella flexneri 2a vaccine with and without dmLT …
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Shigella Flexneri 2a Invaplex 50 Vaccine Dose Finding and Assessment of Protection [Phase 1, Phase 2]
Phase 1/2 trial exploring dose finding and protection assessment for Shigella flexneri 2a Invaplex 50 vaccine; results completed with posted…
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CLINICAL_TRIALS withdrawal · 2017-07-02Clinical Trial Update: Shigella Sonnei OSPC-rDT Conjugate Vaccine [Phase 1]
A Phase 1 trial of the Shigella Sonnei OSPC-rDT Conjugate Vaccine has been withdrawn from the study registry.
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders
This completed clinical trial update reports on diagnosing a range of neglected tropical diseases in patients with persistent digestive diso…
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CLINICAL_TRIALS trial_result · 2016-06-21Clinical Trial Update: Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy Adults [Phase 1]
Phase 1 study evaluating a Shigella sonnei vaccine administered by intradermal, intranasal, or intramuscular routes in healthy adults has be…
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: Safety and Tolerability of a Bioconjugate Vaccine Against Shigella Flexneri 2a [Phase 1]
A Phase 1 study evaluating the safety and tolerability of a bioconjugate vaccine targeting Shigella flexneri 2a has completed.
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CLINICAL_TRIALS research · 2015-08-06Clinical Trial Update: The Long Term Clinical Course of Postinfectious Irritable Bowel Syndrome After Shigellosis; A 10 Year Follow up Study
A 10-year follow-up study documents the long-term outcomes of individuals with postinfectious irritable bowel syndrome after Shigella sonnei…
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CLINICAL_TRIALS research · 2012-07-11Clinical Trial Update: Identification of Correlates of Protection Against Shigella and Enterotoxigenic Escherichia Coli Infections [NA]
A clinical trial update identifying immune correlates of protection against Shigella and Enterotoxigenic Escherichia coli infections (dysent…
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CLINICAL_TRIALS trial_result · 2012-06-19Clinical Trial Update: Safety, Immunogenicity and Efficacy of Shigella Conjugate Vaccines in 1-4 Year Olds in Israel [Phase 3]
Phase 3 trial evaluating safety, immunogenicity, and efficacy of Shigella conjugate vaccines in 1-4 year olds in Israel. The study is comple…
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CLINICAL_TRIALS trial_result · 2011-12-08Clinical Trial Update: Therapeutic Induction of Endogenous Antibiotics [Phase 2]
Phase 2 clinical trial evaluating induction of endogenous antibiotics for treatment of shigellosis has completed.
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: Safety and Reactogenicity of Bioconjugate Vaccine to Prevent Shigella [Phase 1]
Phase 1 study assessing the safety and reactogenicity of a Shigella bioconjugate vaccine developed by GlycoVaxyn AG.
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FDA approval · 2010-02-16FDA Approved: SULFAMETHOXAZOLE AND TRIMETHOPRIM — Original Application (Rising Pharma Holdings, Inc.)
FDA approved Rising Pharma Holdings, Inc.'s generic product Sulfamethoxazole and Trimethoprim as an Original Application (ANDA).
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FDA label_change · 2007-06-05FDA Approved: BACTRIM — Supplemental Application (Sun Pharmaceutical Industries, Inc)
FDA approved a supplemental application for BACTRIM (sulfamethoxazole and trimethoprim) to modify the labeling.
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CLINICAL_TRIALS trial_result · 2006-05-03Clinical Trial Update: Zinc Supplementation in Shigella Patients [Phase 3]
A Phase 3 trial evaluating zinc supplementation in patients with Shigella infection has completed.