Shigellosis
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CLINICAL_TRIALS trial_result · 2026-06-22Clinical Trial Results: A Study on the Safety and Immune Responses to the GVGH altSonflex1-2-3 Vaccine Against Shigellosis in Adults, Children, and Infants [Phase 1, Phase 2]
Phase 1/2 trial results for the GVGH altSonflex1-2-3 vaccine targeting diarrhoea caused by Shigella, assessing safety and immune responses i…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Human Challenge Study to Assess Protection of a Shigella Tetravalent Bioconjugate Vaccine [Phase 2]
A Phase 2 human challenge trial update evaluating protection from LimmaTech Biologics' Shigella tetravalent bioconjugate vaccine. The study …
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Study to Expand Safety and Immunogenicity Data With Shigella Bioconjugate Vaccine (Shigella4V2) in 9-month-old Infants. [Phase 2]
A Phase 2 study updating safety and immunogenicity data for the Shigella4V2 bioconjugate vaccine in 9-month-old infants has completed.
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Shigella CVD 31000: Study of Responses With Shigella-ETEC Vaccine Strain CVD 1208S-122 [Phase 1]
Phase 1 study of the Shigella-ETEC vaccine strain CVD 1208S-122 (CVD 31000) completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants [Phase 2]
Phase 2 study evaluating the immune response and safety of a multicomponent Shigella vaccine to prevent shigellosis in infants; the trial ha…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Long-Term Immunogenicity of the altSonflex1-2-3 Shigella Vaccine in African Children [Phase 2]
Clinical Trial Update describing the long-term immunogenicity of the altSonflex1-2-3 Shigella Vaccine in African children in a Phase 2 study…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: A Study on the Safety and Immune Responses to the GVGH altSonflex1-2-3 Vaccine Against Shigellosis in Adults, Children, and Infants [Phase 1]
A Phase 1 study completed evaluating the safety and immune responses of the GVGH altSonflex1-2-3 vaccine against Shigellosis in adults, chil…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Tebipenem Trial in Children With Shigellosis [Phase 2]
A Phase 2 trial evaluating tebipenem in children with shigellosis is currently listed as active but not recruiting on ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Safety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of Shigellosis [Phase 1, Phase 2]
Clinical trial update on the safety and efficacy of ShigActive, a bacteriophage product, in a human experimental model of Shigellosis (Phase…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Phase 2 Shigella Vaccine and Challenge [Phase 2]
Phase 2 trial of a Shigella vaccine has completed and results have been posted. The study was sponsored by the National Institute of Allergy…
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: Controlled Human Infection Model Challenge/Rechallenge [Phase 1]
Phase 1 trial update for a controlled human infection model using challenge/rechallenge design in Shigellosis; the study is completed with r…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: InvaplexAR-Detox and DmLT Adjuvant in the Netherlands and Zambia [Phase 1]
Phase 1 clinical trial update for InvaplexAR-Detox and DmLT Adjuvant conducting recruitment in the Netherlands and Zambia for shigellosis an…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: A Study to Determine If a New Shigella Vaccine is Safe, Induces Immunity and The Best Dose Among Kenyan Infants [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating safety, immunogenicity, and optimal dosing of a new Shigella vaccine in Kenyan infants has completed.
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Shigella CVD 30000: Study of Responses to Vaccination With Shigella Vaccine [Phase 2]
A Phase 2 clinical trial evaluating responses to vaccination with Shigella vaccine CVD 30000 has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: A Study to Investigate the Safety and Immunogenicity of the SF2a-TT15 Synthetic Carbohydrate-based Conjugate Vaccine Against Shigella Flexneri 2a [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of a Shigella vaccine (SF2a-TT15) completed.
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery [Phase 4]
A phase 4 trial comparing ciprofloxacin to azithromycin for children hospitalized with dysentery due to Shigella has completed.
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Efficacy, Immunogenicity and Safety of S. Flexneriza-S. Sonnei Bivalent Conjugate Vaccine in Volunteers Aged From 6 Months to 5 Years [Phase 3]
Phase 3 clinical trial update evaluating efficacy, immunogenicity, and safety of a bivalent Shigella vaccine in children aged 6 months to 5 …
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CLINICAL_TRIALS trial_result · 2021-08-11Clinical Trial Update: Safety Study of Inactivated Shigella Whole Cell Vaccine in Adults [Phase 1]
Phase 1 safety study of an inactivated Shigella whole cell vaccine completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Phase 2b Challenge Study With the Bioconjugate Vaccine Flexyn2a [Phase 2]
Phase 2b trial of the bioconjugate vaccine Flexyn2a for Shigellosis completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-07-22Clinical Trial Update: Safety and Immunogenicity of Artificial Invaplex (Shigella Flexneri 2a InvaplexAR) [Phase 1]
Phase 1 clinical trial assessing safety and immunogenicity of artificial Invaplex for Shigella flexneri 2a; results posted after completion.
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CLINICAL_TRIALS trial_result · 2019-02-18Clinical Trial Update: A Study of the Safety and Immune Response of 2 Doses of a New Shigella Vaccine in Kenyan Adults [Phase 2]
Phase 2 trial evaluating the safety and immune response of two-dose Shigella vaccine in Kenyan adults. The study is completed with results p…
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: Safety and Immunogenicity of Two Live, Attenuated Oral Shigella Sonnei Vaccines: WRSs2 and WRSs3 [Phase 1]
A Phase 1 trial evaluating safety and immunogenicity of two live, attenuated oral Shigella Sonnei vaccines, WRSs2 and WRSs3.
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: A Phase 1, Dose Escalation Study, to Evaluate a New Shigella Sonnei Vaccine in Healthy Adults. [Phase 1]
Phase 1 dose-escalation study of a Shigella sonnei vaccine in healthy adults has completed and results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-11-13Clinical Trial Update: Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate [Phase 1, Phase 2]
Clinical trials for WRSS1, a Shigella sonnei vaccine candidate, completed Phase 1/2 to assess safety and efficacy for dysentery caused by Sh…
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: SF2a-TT15 Conjugate Vaccine in Healthy Adult Volunteers [Phase 1]
Phase 1 clinical trial update shows completion of a Phase 1 study of the SF2a-TT15 Conjugate Vaccine in healthy adult volunteers. The study …