Sezary Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatment [Phase 1, Phase 2]
The NCI-announced Phase 1/2 trial testing magrolimab added to mogamulizumab for recurrent or refractory Mycosis Fungoides/Sezary Syndrome wa…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating durvalumab with or without lenalidomide in patients with relapsed or refractory cutaneous or periph…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides [Phase 2]
Phase 2 trial evaluating pembrolizumab in patients with stage IB-IV mycosis fungoides and Sezary syndrome has completed, with results posted…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Mogamulizumab and Extracorporeal Photopheresis for the Treatment of Sezary Syndrome or Mycosis Fungoides [Phase 1, Phase 2]
Phase 1/2 study of mogamulizumab in combination with extracorporeal photopheresis for Sezary syndrome and mycosis fungoides was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab [Phase 2]
Phase 2 trial evaluating letermovir for prevention of cytomegalovirus reactivation in patients with hematologic malignancies treated with al…
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: Ph II of Non-myeloablative Allogeneic Transplantation Using TLI & ATG In Patients w/ Cutaneous T Cell Lymphoma [Phase 2]
Phase 2 clinical trial update for non-myeloablative allogeneic transplantation using TLI and ATG in patients with cutaneous T-cell lymphoma …
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CLINICAL_TRIALS trial_result · 2022-09-13Clinical Trial Update: Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies [Phase 1]
Phase 1 trial evaluating interleukin-15 in combination with avelumab in relapsed/refractory mature T-cell malignancies completed; results po…
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CLINICAL_TRIALS trial_result · 2021-12-14Clinical Trial Update: Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrome [Phase 1]
Phase I trial evaluating recombinant human IL-15 in combination with mogamulizumab for refractory/relapsed adult T-cell leukemia/lymphoma an…
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CLINICAL_TRIALS trial_result · 2020-02-24Clinical Trial Update: Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated Campath-1H–mediated stem cell transplant therapy for advanced Mycosis Fungoides and Sezary Syndrome; th…
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: Dose-Escalation Trial of Carfilzomib With and Without Romidepsin in Cutaneous T-Cell Lymphoma [Phase 1]
A Phase 1 dose-escalation study evaluating carfilzomib with and without romidepsin in cutaneous T-cell lymphoma (CTCL) was terminated with r…
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CLINICAL_TRIALS trial_result · 2019-05-16Clinical Trial Update: Silicon Phthalocyanine 4 and Photodynamic Therapy in Stage IA-IIA Cutaneous T-Cell Non-Hodgkin Lymphoma [Phase 1]
Phase 1 trial assessing Silicon Phthalocyanine 4 with photodynamic therapy in recurrent cutaneous T-cell lymphoma including mycosis fungoide…
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: Pembrolizumab in Treating Patients With Relapsed or Refractory Stage IB-IVB Mycosis Fungoides or Sezary Syndrome [Phase 2]
Phase 2 trial of pembrolizumab in relapsed or refractory mycosis fungoides or Sezary syndrome completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Brentuximab Vedotin (SGN-35) in Patients With Mycosis Fungoides With Variable CD30 Expression Level [Phase 2]
Phase 2 trial results of brentuximab vedotin (SGN-35) in patients with mycosis fungoides/cutaneous T-cell lymphoma with variable CD30 expres…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: A-dmDT390-bisFv(UCHT1) Immunotoxin Therapy for Patients With Cutaneous T-Cell Lymphoma (CTCL) [Phase 2]
Phase 2 trial of A-dmDT390-bisFv(UCHT1) immunotoxin for cutaneous T-cell lymphoma (CTCL) has completed, with results from the study summariz…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Combination Drug Study of Bexarotene and Rosiglitazone to Treat CTCL [Phase 2]
A Phase 2 trial investigating a combination of bexarotene and rosiglitazone for cutaneous T-cell lymphoma has been completed, with results p…
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CLINICAL_TRIALS trial_result · 2015-03-23Clinical Trial Update: O6-Benzylguanine and Topical Carmustine in Treating Patients With Early-Stage IA-IIA Cutaneous T-Cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 trial assessed the combination of O6-Benzylguanine with topical Carmustine in patients with early-stage cutaneous T-cell lymphom…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas [Phase 1]
This Phase 1 trial evaluated entinostat (MS-275) plus isotretinoin in adults with metastatic or advanced solid tumors or various lymphomas; …
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: 506U78 in Treating Patients With Recurrent or Refractory Cutaneous T-cell Lymphoma [Phase 2]
A Phase 2 trial evaluating 506U78 for recurrent or refractory cutaneous T-cell lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: 506U78 in Treating Patients With Lymphoma [Phase 2]
Phase 2 clinical trial update on the agent 506U78 for various lymphomas; the study has completed.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Interleukin-12 and Interleukin-2 in Treating Patients With Mycosis Fungoides [Phase 1, Phase 2]
Phase 1/2 trial evaluating interleukin-12 and interleukin-2 in patients with mycosis fungoides and Sezary syndrome. The study was terminated…
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CLINICAL_TRIALS trial_result · 2008-03-05Clinical Trial Update: Study of ONTAK (Denileukin Diftitox) in Previously Treated Cutaneous T-Cell Lymphoma Patients [Phase 4]
Phase 4 clinical trial update of ONTAK (denileukin diftitox) in patients with previously treated cutaneous T-cell lymphoma, including Mycosi…