Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2009-07-03Clinical Trial Update: Bacteremia in Intensive Care Unit (ICU)
Clinical trial update on bacteremia and sepsis in ICU patients, with emphasis on Toll-Like Receptors (TLRs); no status information is provid…
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CLINICAL_TRIALS research · 2009-06-26Clinical Trial Update: Statin for Immunomudulation in Sepsis [Phase 2]
Phase 2 clinical trial evaluating a statin for immunomodulation in sepsis. The current status is unknown.
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FDA approval · 2009-06-18FDA Approved: CEFTRIAXONE — Supplemental Application (Baxter Healthcare Company)
FDA approved a supplemental application for ceftriaxone sodium (ceftriaxone) from Baxter Healthcare Company, authorizing changes to the appr…
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CLINICAL_TRIALS research · 2009-05-27Clinical Trial Update: The Role of Angiopoietin, Tie-2, and Vascular Endothelial Growth Factor (VEGF) in Sepsis-Induced Multiple Organ Dysfunction Syndrome (MODS)
This document discusses the roles of angiopoietin, Tie-2, and VEGF in sepsis-induced multiple organ dysfunction syndrome and references a cl…
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CLINICAL_TRIALS trial_result · 2009-02-11Clinical Trial Update: The AOT (Acridine Orange and Taurolidine) Trial [Phase 3]
Phase 3 trial evaluating Acridine Orange and Taurolidine (AOT) for infection/sepsis related to parenteral nutrition has completed.
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CLINICAL_TRIALS research · 2009-02-05Clinical Trial Update: Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury [Phase 4]
This is a status update on an ongoing Phase 4 trial evaluating early continuous renal replacement therapy in patients with severe sepsis or …
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CLINICAL_TRIALS trial_result · 2009-01-14Clinical Trial Update: Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation [NA]
This entry notes that the National Institute of General Medical Sciences–sponsored trial on the optimal endpoint for early sepsis resuscitat…
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CLINICAL_TRIALS trial_result · 2009-01-07Clinical Trial Update: Extracorporeal Immune Support System (EISS) for the Treatment of Septic Patients [Phase 1, Phase 2]
Clinical trial update indicating completion of Phase 1 and Phase 2 studies of the Extracorporeal Immune Support System (EISS) for patients w…
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FDA approval · 2008-12-30FDA Approved: VANCOMYCIN HYDROCHLORIDE — Original Application (Mylan Institutional LLC)
FDA approved the original application for vancomycin hydrochloride from Mylan Institutional LLC, marking the approval of a generic injectabl…
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CLINICAL_TRIALS trial_result · 2008-12-24Clinical Trial Update: MicroPhage S. Aureus / MSSA / MRSA Blood Culture Beta Trial
A completed beta trial by MicroPhage, Inc. evaluating phage therapy against Staphylococcus aureus bacteremia (MSSA/MRSA) using blood culture…
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CLINICAL_TRIALS research · 2008-12-02Clinical Trial Update: The Biomarker and Cardiac Function in Sepsis
This document provides an update on a National Taiwan University Hospital clinical trial investigating biomarkers and cardiac function in pa…
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CLINICAL_TRIALS trial_result · 2008-12-02Clinical Trial Update: Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis [Phase 4]
Phase 4 trial evaluating Polymyxin B hemoperfusion in abdominal sepsis has completed.
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CLINICAL_TRIALS trial_result · 2008-10-27Clinical Trial Update: The Effect of Glutamine on Systemic Inflammation During Human Experimental Endotoxemia [NA]
A completed clinical trial evaluating the effect of glutamine on systemic inflammation in humans undergoing an endotoxemia model.
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CLINICAL_TRIALS trial_result · 2008-10-16Clinical Trial Update: Pathogenesis and Cerebrovascular Manifestations of Septic Encephalopathy
This clinical trial update notes the completion of a study examining the pathogenesis and cerebrovascular manifestations of septic encephalo…
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CLINICAL_TRIALS trial_result · 2008-07-16Clinical Trial Update: The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis [Phase 3]
A Phase 3 clinical trial assessing nitroglycerin for correcting microcirculatory abnormalities in sepsis and septic shock has completed.
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CLINICAL_TRIALS trial_result · 2008-07-08Clinical Trial Update: Procalcitonin-Guided Antimicrobial Discontinuation [Phase 4]
Phase 4 clinical trial evaluating procalcitonin-guided antimicrobial discontinuation in sepsis has completed. The study investigates whether…
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CLINICAL_TRIALS research · 2008-06-17Clinical Trial Update: Bacterial Infection Diagnosis Using Blood DNA
This entry notes an ongoing clinical trial investigating a blood DNA test to diagnose bacterial infections, including sepsis, with an unknow…
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CLINICAL_TRIALS research · 2008-06-16Clinical Trial Update: Ambisome® Preemptive Treatment of Multiple Candida Colonization in Sepsis Patients [Phase 4]
Phase 4 clinical trial update evaluating preemptive treatment with Ambisome (liposomal amphotericin B) to prevent Candida colonization in se…
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CLINICAL_TRIALS trial_result · 2008-06-10Clinical Trial Update: Leukocyte Depletion of Autologous Whole Blood [Phase 4]
This Phase 4 trial evaluating leukocyte depletion of autologous whole blood in patients with bacterial infections and sepsis has completed.
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CLINICAL_TRIALS research · 2008-06-05Clinical Trial Update: Skeletal Muscle Oxygenation in Critically Ill
A clinical trial update from University Medical Centre Ljubljana examining skeletal muscle oxygenation in critically ill patients, including…
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CLINICAL_TRIALS withdrawal · 2008-05-29Clinical Trial Update: Methylene Blue in Sepsis: A Randomized Controlled Trial [NA]
A randomized controlled trial evaluating methylene blue for sepsis has been withdrawn. This update confirms the study status as withdrawn.
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CLINICAL_TRIALS trial_result · 2008-05-14Clinical Trial Update: Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment With Corticosteroids
A completed clinical trial update examining the time course of procalcitonin and C-reactive protein in septic patients treated with corticos…
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CLINICAL_TRIALS trial_result · 2008-05-09Clinical Trial Update: Cortisol Control of Human Inflammatory Responses to Endotoxin [NA]
The trial evaluating cortisol's ability to regulate inflammatory responses to endotoxin in sepsis has completed. No results are provided in …
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CLINICAL_TRIALS research · 2008-03-24Clinical Trial Update: Acute Phase Proteins as Early Markers in Sepsis
A clinical trial update about evaluating acute phase proteins as early biomarkers for sepsis; the current trial status is unknown and the sp…
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CLINICAL_TRIALS research · 2008-03-18Clinical Trial Update: Are the Pancreatic Serum Proteins Pancreatic Stone Protein (PSP) and Pancreatitis-Associated Protein (PAP) Predictive for the Development of Sepsis? Retrospective Study in Trauma Patients With Soft Tissue Defects.
A retrospective study from University of Zurich investigates whether the pancreatic serum proteins Pancreatic Stone Protein (PSP) and Pancre…