Sepsis
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CLINICAL_TRIALS trial_result · 2010-07-07Clinical Trial Update: A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult [NA]
A randomized trial evaluating the safety and efficacy of GR270774 for Gram-negative sepsis in adults has been suspended.
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CLINICAL_TRIALS research · 2010-07-02Clinical Trial Update: Innate Immune Functions of Immature Neutrophils
This entry reports a clinical trial evaluating the innate immune functions of immature neutrophils and their relevance to sepsis and systemi…
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CLINICAL_TRIALS trial_result · 2010-06-04Clinical Trial Update: The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial [Phase 3]
A Phase 3 randomized trial evaluated whether Polymyxin B protects against sepsis-induced kidney dysfunction; results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-05-31Clinical Trial Update: Neutrophile Gelatinase Associated Lipocalin Evaluation in Septic Acute Kidney Injury
A clinical trial update examining neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in septic acute kidney injury.
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CLINICAL_TRIALS trial_result · 2010-04-14Clinical Trial Update: Fluid Resuscitation in Early Septic Shock [Phase 2]
This is a Phase 2 trial update on fluid resuscitation for early septic shock, with the study status showing as completed.
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CLINICAL_TRIALS trial_result · 2010-03-05Clinical Trial Update: Vitamin D Zinc Fever
This document reports an update on a clinical trial studying Vitamin D and zinc for sepsis and fever, with the trial status currently unknow…
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CLINICAL_TRIALS trial_result · 2010-03-04Clinical Trial Update: The Procalcitonin and Survival Study [NA]
A completed clinical trial evaluating procalcitonin-guided management in patients with localized infection and sepsis, including those with …
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CLINICAL_TRIALS trial_result · 2010-02-26Clinical Trial Update: Cysteine Supplementation in Critically Ill Neonates [Phase 2, Phase 3]
Clinical trial update for cysteine supplementation in critically ill neonates spanning Phase 2 and Phase 3, with multiple neonatal condition…
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CLINICAL_TRIALS trial_result · 2010-02-18Clinical Trial Update: Use of Non Invasive Hemodynamic Cardiovascular Monitoring to Evaluate Emergency Department Patients
A completed trial evaluating non-invasive hemodynamic cardiovascular monitoring to assess emergency department patients across several condi…
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CLINICAL_TRIALS trial_result · 2010-02-17Clinical Trial Update: Mild Therapeutic Hypothermia During Severe Sepsis [NA]
The document reports a completed clinical trial investigating mild therapeutic hypothermia in patients with sepsis. No efficacy results are …
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CLINICAL_TRIALS trial_result · 2010-02-04Clinical Trial Update: Terlipressin in Septic Shock: Effects on Microcirculation [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluating terlipressin for septic shock, focusing on its effects on microcirculation, have completed.
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CLINICAL_TRIALS trial_result · 2010-02-02Clinical Trial Update: Follow-up Data of Patients Treated With XIGRIS® in France
Follow-up data from a France-based clinical study evaluating XIGRIS (drotrecogin alfa (activated)) in patients with sepsis.
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CLINICAL_TRIALS research · 2010-01-12Clinical Trial Update: Study of Hemodynamics of Neonates by Echocardiography and USCOM
A neonatal hemodynamics study using echocardiography and USCOM is being conducted, sponsored by Guangdong Provincial People's Hospital, with…
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CLINICAL_TRIALS trial_result · 2009-12-31Clinical Trial Update: The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis [Phase 4]
Phase 4 clinical trial update evaluating the effects of eicosapentaenoic acid (EPA), gamma-linolenic acid (GLA) and antioxidants in the trea…
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CLINICAL_TRIALS research · 2009-10-15Clinical Trial Update: Effect of Intraoperative Fluid Restriction on Postoperative Outcomes in Video-assisted Thoracic Surgery (VATS) [NA]
This clinical trial update describes a study on intraoperative fluid restriction during video-assisted thoracic surgery (VATS) to assess pos…
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CLINICAL_TRIALS research · 2009-10-14Clinical Trial Update: Thromboelastography in in Patients With Sepsis
This document updates a clinical trial evaluating thromboelastography in patients with sepsis. It notes conditions such as shock and Systemi…
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CLINICAL_TRIALS trial_result · 2009-09-29Clinical Trial Update: Extravascular Lung Water Index in Severe Sepsis [NA]
A clinical trial evaluating Extravascular Lung Water Index in patients with severe sepsis has completed.
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CLINICAL_TRIALS trial_result · 2009-09-15Clinical Trial Update: Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis [Phase 3]
Phase 3 randomized trial comparing normal saline to Voluven for fluid resuscitation in severe sepsis has completed.
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CLINICAL_TRIALS research · 2009-09-09Clinical Trial Update: Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit
An update on a clinical trial investigating oxidative stress in critically ill patients in the surgical intensive care unit, focusing on sep…
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CLINICAL_TRIALS trial_result · 2009-09-03Clinical Trial Update: Sepsis, Endothelial Function, and Lipids in Critically Ill Patients With Liver Failure (the SELLIFA Study)
This entry notes that the SELLIFA study investigating sepsis, endothelial function, and lipids in critically ill patients with liver failure…
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CLINICAL_TRIALS trial_result · 2009-08-25Clinical Trial Update: Immunoadsorption of LPS, C5a and IL-6 in Severe Sepsis and Septic Shock (ISASS-1) [Phase 2, Phase 3]
The ISASS-1 trial evaluating immunoadsorption to remove LPS, C5a, and IL-6 in severe sepsis and septic shock has completed Phase 2 and Phase…
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CLINICAL_TRIALS trial_result · 2009-08-17Clinical Trial Update: Hemodynamic and Perfusion Response to Drotrecogin Alfa (Activated) in Patients With Septic Shock [Phase 4]
Phase 4 trial update on drotrecogin alfa (activated) examines hemodynamic and perfusion responses in patients with septic shock; results wer…
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CLINICAL_TRIALS trial_result · 2009-08-13Clinical Trial Update: Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis [Phase 4]
Phase 4 clinical trial update evaluating fish oil–based lipid emulsion infusions in critically ill patients with severe sepsis; the study st…
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CLINICAL_TRIALS research · 2009-08-06Clinical Trial Update: Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT
This clinical trial update examines citrate pharmacokinetics and regional citrate anticoagulation during CRRT in patients with acute kidney …
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CLINICAL_TRIALS trial_result · 2009-07-15Clinical Trial Update: A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.
The document notes the completion of a clinical trial evaluating a non-invasive method to assess volume status in mechanically ventilated pa…