Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-08-12Clinical Trial Update: BaSES Trial: Basel Starch Evaluation in Sepsis [Phase 4]
Phase 4 trial evaluating hydroxyethyl starch for sepsis has completed (BaSES trial).
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO
This completed clinical trial evaluated whether the biomarkers sTREM-1, procalcitonin (PCT), and C-reactive protein (CRP) can detect sepsis …
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Clarithromycin as Immunomodulator for the Management of Sepsis [Phase 3]
Phase 3 trial evaluating clarithromycin as an immunomodulator for sepsis (including severe sepsis and septic shock) has completed.
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Lipid Profile in Patients With Severe Sepsis or Septic Shock Under Strict or Liberal Glycemic Control [NA]
An update on a completed clinical trial evaluated lipid profiles in patients with severe sepsis or septic shock under strict versus liberal …
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CLINICAL_TRIALS withdrawal · 2011-08-04Clinical Trial Update: Impact of Clinical, Demographic and Laboratory Variables on Brain Natriuretic Peptide Levels
The trial evaluating factors that influence brain natriuretic peptide levels in patients with sepsis or heart failure has been withdrawn fro…
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries
A completed clinical trial investigating soluble TREM-1 in sepsis and related acute kidney injury conditions; no results are described in th…
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis [Phase 3]
A Phase 3 trial evaluated Voluven for its effects on hemodynamics and tolerability of enteral nutrition in patients with severe sepsis, with…
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CLINICAL_TRIALS trial_result · 2011-08-01Clinical Trial Update: Diagnostic Value of sTREM-1 and PCT Level as Well as CPIS Score for Ventilator-Associated Pneumonia Among ICU Sepsis Patients
This clinical trial update reports an evaluation of sTREM-1 and procalcitonin levels, along with the CPIS score, for diagnosing ventilator-a…
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Renal Impairment Associated With Colistin Levels
A completed clinical trial update notes that higher colistin exposure is associated with renal impairment, highlighting a safety considerati…
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CLINICAL_TRIALS trial_result · 2011-07-11Clinical Trial Update: The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation [Phase 4]
A completed Phase 4 trial from the Medical University of Vienna evaluated the role of the P2Y12 receptor in tissue factor–induced coagulatio…
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CLINICAL_TRIALS research · 2011-07-07Clinical Trial Update: Comparison the Value of Several Biomarkers of Sepsis
This clinical trial update reports the completion of a study comparing the value of several biomarkers for sepsis and systemic inflammatory …
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CLINICAL_TRIALS research · 2011-06-23Clinical Trial Update: Angiotensin in Septic Kidney Injury Trial [Phase 2]
Phase 2 clinical trial evaluating angiotensin for septic kidney injury is ongoing, with current status not provided.
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CLINICAL_TRIALS trial_result · 2011-06-21Clinical Trial Update: Outcome Predictors in Patients With Severe Sepsis and Optimized Central Venous Oxygen Saturation
A completed clinical trial evaluating predictors of outcomes in patients with severe sepsis treated to optimize central venous oxygen satura…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity [Phase 3]
Phase 3 clinical trial evaluating probiotics to prevent preterm birth and related neonatal morbidity was terminated.
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CLINICAL_TRIALS trial_result · 2011-06-14Clinical Trial Update: Efficacy of Thymosin alpha1 for Severe Sepsis [NA]
The clinical trial evaluating thymosin alpha-1 for severe sepsis has completed; the update does not report efficacy results.
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CLINICAL_TRIALS trial_result · 2011-06-07Clinical Trial Update: Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis [NA]
A completed clinical trial evaluating the CytoSorb hemoperfusion device for removing interleukin-6 in patients with acute respiratory distre…
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CLINICAL_TRIALS research · 2011-06-03Clinical Trial Update: Exercise in Critically Ill Patients With Sepsis [NA]
This clinical trial update concerns exercise interventions in critically ill patients with sepsis. The current study status is unknown.
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CLINICAL_TRIALS trial_result · 2011-05-26Clinical Trial Update: Reconstruction of Monocytic Immunocompetence by Granulocyte-macrophage-colony Stimulating Factor (GM-CSF) in Patients With Severe Sepsis and Septic Shock [Phase 2]
Phase 2 clinical trial evaluating whether granulocyte-macrophage colony-stimulating factor (GM-CSF) can restore monocytic immune competence …
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CLINICAL_TRIALS trial_result · 2011-05-18Clinical Trial Update: Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation [Phase 2]
Phase 2 study evaluating ART-123 for safety and efficacy in sepsis with disseminated intravascular coagulation has completed.
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CLINICAL_TRIALS trial_result · 2011-04-11Clinical Trial Update: Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis
A completed clinical trial evaluating the impact of hydrocortisone on white blood cell gene expression in patients with severe sepsis and re…
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CLINICAL_TRIALS trial_result · 2011-04-11Clinical Trial Update: Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis
This completed clinical trial studied microcirculatory changes during magnesium sulfate infusion in patients with sepsis, including severe s…
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CLINICAL_TRIALS trial_result · 2011-04-05Clinical Trial Update: The Effects of HIV Protease Inhibitors in Severe Sepsis [Phase 1]
A Phase 1 trial conducted by Mayo Clinic evaluated the effects of HIV protease inhibitors in patients with severe sepsis. The study status i…
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CLINICAL_TRIALS research · 2011-03-11Clinical Trial Update: Early Goal-directed Therapy and Myocardial Dysfunction [NA]
Clinical trial update on early goal-directed therapy for sepsis with myocardial dysfunction; current status is unknown.
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CLINICAL_TRIALS trial_result · 2011-03-09Clinical Trial Update: Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock [Phase 4]
A Phase 4 clinical trial evaluated strategies to improve tissue oxygenation with the goal of reducing mortality in severe sepsis and septic …
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CLINICAL_TRIALS trial_result · 2011-03-02Clinical Trial Update: Paracetamol Toxicity in Septic Patients [Phase 3]
A Phase 3 study evaluating paracetamol toxicity in septic patients has been suspended.