Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2012-02-13Clinical Trial Update: Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis [Phase 4]
This Phase 4 clinical trial comparing hydrocortisone alone versus hydrocortisone plus fludrocortisone for adrenal insufficiency in severe se…
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CLINICAL_TRIALS other · 2012-02-03Clinical Trial Update: Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis [Phase 2, Phase 3]
A Phase 2/3 trial of talactoferrin alfa in patients with severe sepsis has been suspended, with ongoing assessment of safety and efficacy.
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CLINICAL_TRIALS trial_result · 2012-02-02Clinical Trial Update: Efficacy & Safety of Resatorvid in Adults With Severe Sepsis [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of resatorvid in adults with severe sepsis has completed.
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CLINICAL_TRIALS trial_result · 2012-01-18Clinical Trial Update: Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection [Phase 4]
A Phase 4 trial evaluating the use of procalcitonin levels to guide stopping antibiotics in ICU patients with no obvious site of infection w…
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: Extracardiac Complications After Cardiac Surgery
A completed clinical trial from the University of Turin assessing extracardiac complications after cardiac surgery, including Acute Lung Inj…
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU
A completed clinical trial evaluating a hematological infection score versus the hospital standard for diagnosing systemic inflammatory resp…
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CLINICAL_TRIALS research · 2012-01-05Clinical Trial Update: Association Between cd163 Gene Polymorphisms and Sepsis Among Chinese Han Population
This clinical trial update examines whether CD163 gene polymorphisms are associated with sepsis in people of Chinese Han ethnicity.
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CLINICAL_TRIALS research · 2012-01-04Clinical Trial Update: Biomarkers in Exhaled Breath Condensates of Septic Patients to Predict Development of Multi-organ Dysfunction Syndrome
This entry reports an ongoing clinical trial evaluating biomarkers in exhaled breath condensate from septic patients to predict progression …
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CLINICAL_TRIALS research · 2011-12-30Clinical Trial Update: The Impact of Continuous Renal Replacement Therapy on the Outcomes of Burn Patients With Early Phase of Sepsis [NA]
A clinical trial from Southwest Hospital, China investigates whether continuous renal replacement therapy affects outcomes in burn patients …
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CLINICAL_TRIALS trial_result · 2011-12-29Clinical Trial Update: Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections [Phase 4]
A Phase 4 trial evaluated diagnosing septicaemia in severe infections by detecting microbial DNA in blood, involving febrile neutropenia, en…
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CLINICAL_TRIALS trial_result · 2011-12-19Clinical Trial Update: Procalcitonin as a Tool to Shorten Antibiotic Therapy in the ICU [NA]
A completed ICU trial evaluated using procalcitonin levels to guide shortening antibiotic therapy in sepsis and reported whether this approa…
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CLINICAL_TRIALS research · 2011-12-19Clinical Trial Update: The Changes of CD4+T Lymphocyte Subsets in Septic Patients
This clinical trial update discusses how CD4+ T lymphocyte subsets change in patients with sepsis and systemic inflammatory response syndrom…
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CLINICAL_TRIALS research · 2011-12-16Clinical Trial Update: Urinary Proteomics Analysis for Sepsis and Prognosis
Clinical trial update exploring urinary proteomics as a predictor for sepsis prognosis.
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CLINICAL_TRIALS research · 2011-12-16Clinical Trial Update: Serum Proteomics Analysis for Sepsis
An update on a serum proteomics study for sepsis conducted at Chinese PLA General Hospital, with no status or results reported.
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CLINICAL_TRIALS trial_result · 2011-12-13Clinical Trial Update: TREM-1 Gene Polymorphisms
This document reports the completion of a clinical trial studying TREM-1 gene polymorphisms in patients with sepsis. The sponsor listed is t…
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CLINICAL_TRIALS research · 2011-12-06Clinical Trial Update: Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe Sepsis
A pharmacogenomic biomarker study is being conducted to evaluate recombinant human activated protein C for treatment in patients with severe…
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CLINICAL_TRIALS trial_result · 2011-11-24Clinical Trial Update: The Effects of Linezolid and Vancomycin on Inflammation and Cellular Signaling Vents
A completed clinical trial update examining the effects of linezolid and vancomycin on inflammation and cellular signaling in sepsis. The st…
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CLINICAL_TRIALS trial_result · 2011-10-27Clinical Trial Update: Colombia Epidemiologic Surveillance Study
Pfizer-sponsored Colombia Epidemiologic Surveillance Study has been terminated. The study investigated Pneumonia, Meningitis, Bacteremia, an…
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CLINICAL_TRIALS research · 2011-10-26Clinical Trial Update: MiRNAs Evaluate the Prognosis of Sepsis by Dynamic Study
A clinical trial evaluating whether microRNAs can dynamically predict prognosis in sepsis.
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EMA withdrawal · 2011-10-25Xigris (drotrecogin alfa (activated)) to be withdrawn due to lack of efficacy
The EMA announces the withdrawal of Xigris (drotrecogin alfa activated) from the market due to lack of efficacy.
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CLINICAL_TRIALS trial_result · 2011-10-06Clinical Trial Update: Indocyanine Clearance Rate and Septic Liver Injury
A clinical trial update from Sun Yat-sen University investigates indocyanine clearance rate in septic liver injury during sepsis. The curren…
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CLINICAL_TRIALS research · 2011-10-05Clinical Trial Update: 4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic Shock
A clinical trial assessing the 4G/5G polymorphism of the plasminogen activator inhibitor-1 (PAI-1) gene and disseminated intravascular coagu…
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CLINICAL_TRIALS trial_result · 2011-09-15Clinical Trial Update: Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease [Phase 3]
A Phase 3 trial evaluating daily zinc supplementation in low birth weight infants has completed, examining its impact on death and severe il…
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CLINICAL_TRIALS trial_result · 2011-09-14Clinical Trial Update: Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients [NA]
The trial evaluated whether a predictive proteic profile could predict mortality in the acute phase of septic shock among cancer patients. T…
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CLINICAL_TRIALS trial_result · 2011-08-23Clinical Trial Update: Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis [Phase 2]
This document reports the completion of a Phase 2 safety and efficacy study evaluating recombinant human lactoferrin for severe sepsis, spon…