Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2016-05-03Clinical Trial Update: Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS) [Phase 2]
A Phase 2 trial evaluating Bevacizumab to prevent acute respiratory distress syndrome in patients with severe sepsis was withdrawn.
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CLINICAL_TRIALS research · 2016-05-02Clinical Trial Update: MiRNAs Evaluating Lymphocyte Proliferation and Apoptosis as Well as Prognosis of Sepsis
A clinical trial update describes evaluating microRNAs that influence lymphocyte proliferation and apoptosis to predict outcomes in sepsis.
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CLINICAL_TRIALS research · 2016-04-29Clinical Trial Update: Molecular Diagnosis and Risk Stratification of Sepsis
This document provides an update on a clinical trial evaluating molecular diagnosis and risk stratification for sepsis.
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CLINICAL_TRIALS trial_result · 2016-04-28Clinical Trial Update: Gluconeogenesis Rates and Its Precursors in Pediatric Sepsis
A completed pediatric sepsis trial examined gluconeogenesis rates and their precursors to better understand glucose metabolism in septic chi…
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CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction [Phase 2]
A Phase 2 trial evaluating a complement inhibitor (vilobelimab/IFX-1) for early septic organ dysfunction has completed.
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Integrilin and Ilomedin in Combination in Comparison to Standard Treatment in Severe Pneumonia Patients With Severe Sepsis [Phase 2]
Phase 2 trial evaluating Integrilin (eptifibatide) plus Ilomedin (iloprost) in combination with standard treatment for patients with severe …
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Effects of Early Exercise Rehabilitation on Long-term Functional Recovery in Patients With Severe Sepsis [NA]
Clinical trial update evaluating whether early exercise rehabilitation improves long-term functional recovery in patients with severe sepsis…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Examination of the Impact of Better Surveillance and Communication of Patient Deterioration on Patient Related Outcomes
A completed Philips Healthcare clinical trial evaluating whether improved surveillance and communication of patient deterioration affects pa…
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Comparison of Sensitivity Between Presepsine and Lactate for the Diagnosis of Severe Sepsis.
Clinical trial update comparing presepsin versus lactate sensitivity for diagnosing severe sepsis and septic shock.
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CLINICAL_TRIALS research · 2016-03-09Clinical Trial Update: Compensatory Reserve Index as a Hemodynamic Status Evaluation Tool in Patients
The document provides an update on a clinical trial evaluating the Compensatory Reserve Index as a tool to assess hemodynamic status in pati…
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CLINICAL_TRIALS research · 2016-03-08Clinical Trial Update: Neonatal Procalcitonin Intervention Study [NA]
An update on a neonatal procalcitonin intervention study investigating sepsis. The trial phase and current status are not specified.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Lymphocyte Count as a Sign of Immunoparalysis and Its Correlation With Nutritional Status in Septic Pediatric Patients
Completed clinical trial update investigating whether lymphocyte count serves as a marker of immunoparalysis in septic pediatric patients an…
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CLINICAL_TRIALS withdrawal · 2016-03-04Clinical Trial Update: Selenium Replacement and Serum Selenium Level in Severe Sepsis and Septic Shock Patients [Phase 2]
Phase 2 clinical trial evaluating selenium replacement in patients with severe sepsis and septic shock has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: The Distribution of Plasma Drug Concentrations of Beta-lactam Antibiotics in Intensive Care Unit Patients
Completed clinical trial update on the distribution of plasma concentrations of beta-lactam antibiotics in ICU patients with sepsis.
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Prognostic Interest of Leucocyte Immunophenotyping During the Acute Phase of Sepsis
A completed clinical trial evaluating whether leukocyte immunophenotyping during the acute phase of sepsis has prognostic value.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: An Observational Study of the Causes, Management, and Outcomes of Community-acquired Sepsis and Severe Sepsis in Southeast Asia
A completed observational study examining the causes, management, and outcomes of community-acquired sepsis and severe sepsis in Southeast A…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Epidemiology of Sepsis in China
Completed clinical trial update reporting epidemiology of sepsis in China.
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) [Phase 3]
Phase 3 trial evaluating volume substitution and insulin therapy for severe sepsis and septic shock has completed.
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CLINICAL_TRIALS trial_result · 2016-02-03Clinical Trial Update: Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections [NA]
A completed clinical trial investigated using inflammatory biomarkers to guide antibiotic therapy in patients with severe infections (severe…
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CLINICAL_TRIALS trial_result · 2016-02-01Clinical Trial Update: Ibuprofen in Sepsis Study [Phase 3]
Phase 3 clinical trial evaluating ibuprofen for sepsis, including septic shock and acute respiratory distress syndrome, has completed.
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients
The completed trial from Chinese PLA General Hospital investigated monocyte/macrophage function and Tim-3 expression in septic patients to c…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis
A completed clinical trial evaluating dynamic changes of Tim-3 on monocytes and soluble Tim-3 in patients with sepsis.
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Biological Markers to Identify Early Sepsis and Acute Lung Injury
The clinical trial update reports the completion of a study investigating biological markers to identify early sepsis and acute lung injury.
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Muscle Atrophy in Patients With Severe Sepsis
A terminated clinical trial evaluated muscle atrophy in patients with severe sepsis, including those with respiratory failure.
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CLINICAL_TRIALS trial_result · 2016-01-06Clinical Trial Update: Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) [NA]
A completed trial evaluates whether procalcitonin-guided antibiotic therapy in adult ICU patients with sepsis improves outcomes compared wit…