Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2016-08-24Clinical Trial Update: Membrane Shedding During Severe Sepsis and Septic Shock: Pathophysiological and Clinical Relevance
A clinical trial update examining membrane shedding in severe sepsis and septic shock, addressing its pathophysiology and potential clinical…
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation [Phase 4]
A Phase 4 clinical trial evaluated midodrine plus albumin to prevent complications in patients with liver cirrhosis awaiting transplantation…
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CLINICAL_TRIALS research · 2016-08-18Clinical Trial Update: Predictive Value of Dynamic Combination of BNP and NGAL for the Prognosis of Patients With Sepsis [NA]
A clinical trial from Southeast University, China evaluated whether a dynamic combination of BNP and NGAL can predict 28-day mortality in pa…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis [Phase 3]
Phase 3 placebo-controlled trial evaluating sodium selenite with procalcitonin-guided antimicrobial therapy in severe sepsis and septic shoc…
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CLINICAL_TRIALS trial_result · 2016-08-09Clinical Trial Update: Impact of Dopamine Infusion on Insulin Secretion in Healthy Subjects [Phase 1]
Phase 1 trial investigated the effect of dopamine infusion on insulin secretion in healthy subjects; the study has completed.
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CLINICAL_TRIALS research · 2016-08-08Clinical Trial Update: Timing of Acute Palliative Care Consultation in Critically Ill Patients [NA]
Clinical trial NCT02858778 from Wayne State University investigates the timing of acute palliative care consultation in critically ill patie…
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CLINICAL_TRIALS trial_result · 2016-07-26Clinical Trial Update: Regression Discontinuity Design to Evaluate of Drotrecogin Alpha Effectiveness
A completed study using regression discontinuity design to evaluate the effectiveness of drotrecogin alfa activated in sepsis.
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CLINICAL_TRIALS research · 2016-07-22Clinical Trial Update: Effects of Dexmedetomidine on Respiratory Function and Inflammatory Responses in Patient With Sepsis Undergoing Cleaning Focus of Infection [NA]
A clinical trial update evaluating the effects of dexmedetomidine on respiratory function and inflammatory responses in a patient with sepsi…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Near Infrared Spectroscopy (NIRS) in Severe Sepsis [Phase 2, Phase 3]
A Phase 2/3 trial evaluating near infrared spectroscopy in severe sepsis has been terminated.
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CLINICAL_TRIALS trial_result · 2016-07-19Clinical Trial Update: SEPSIS 3 Critera for Risk Stratification in Emergency Patients
A completed clinical trial evaluating Sepsis-3 criteria for risk stratification in emergency department patients.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: The AVERT Sepsis Investigation
This ClinicalTrials.gov entry reports that the AVERT Sepsis Investigation trial sponsored by Christiana Care Health Services has completed, …
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CLINICAL_TRIALS research · 2016-06-30Clinical Trial Update: Plasticity and Regeneration of Renal Epithelial Cells
National Taiwan University Hospital is conducting a clinical trial on plasticity and regeneration of renal epithelial cells in sepsis. The c…
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FDA approval · 2016-06-29FDA Approved: CEFTRIAXONE SODIUM — Original Application (Qilu Pharmaceutical Co., Ltd.)
FDA approved the Original Application for ceftriaxone sodium from Qilu Pharmaceutical Co., Ltd., a broad-spectrum cephalosporin used to trea…
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Endothelial Dysfunction and Selenium Status in Children With Acute Systemic Inflammatory Response
This update notes that a pediatric clinical trial evaluating endothelial dysfunction and selenium status in children with acute systemic inf…
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CLINICAL_TRIALS trial_result · 2016-06-13Clinical Trial Update: Cholecalciferol Supplementation for Sepsis in the ICU [Phase 3]
Phase 3 trial evaluating cholecalciferol (vitamin D3) supplementation in ICU patients with sepsis and vitamin D deficiency; the study has co…
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CLINICAL_TRIALS trial_result · 2016-06-13Clinical Trial Update: Effect of Enteral Genistein Supplementation in Sepsis [Phase 4]
An update on a Phase 4 clinical trial evaluating enteral genistein supplementation in patients with sepsis.
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CLINICAL_TRIALS research · 2016-06-09Clinical Trial Update: Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project [NA]
A community-based trial update from Aga Khan University describes a completed project aimed at improving access to emergency obstetric and n…
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture. [Phase 4]
Phase 4 clinical trial update evaluating PCR testing versus conventional blood culture for nosocomial sepsis, bacteremia, and fungemia.
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis [NA]
The document notes the completion of a clinical trial studying the effect of esmolol on prognosis in patients with severe sepsis.
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CLINICAL_TRIALS trial_result · 2016-06-06Clinical Trial Update: Adrenomedullin and Outcome in Severe Sepsis and Septic Shock
A completed clinical trial examined the relationship between adrenomedullin and outcomes in patients with sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2016-06-06Clinical Trial Update: Vitamin D and Critically Ill Patients
This clinical trial update reports on a completed study evaluating Vitamin D supplementation in critically ill patients with systemic inflam…
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CLINICAL_TRIALS withdrawal · 2016-05-17Clinical Trial Update: Gorbly Compression Device for Use in Image-guided Procedures [NA]
The clinical trial involving the Gorbly Compression Device for image-guided procedures has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency Surgery [NA]
A clinical trial evaluating Early Goal-directed Fluid Therapy in septic patients undergoing emergency surgery has been terminated.
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CLINICAL_TRIALS research · 2016-05-12Clinical Trial Update: Correlation Between PTP1B Expression and Organ Failure During Sepsis [NA]
A completed clinical trial from University Hospital, Rouen studied whether PTP1B expression correlates with organ failure in sepsis.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study [Phase 2]
This Phase 2 randomized pilot study evaluated corticosteroid therapy in children with severe sepsis; the trial has completed.