Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-07-14Clinical Trial Update: Vitamin C and Septic Shock [Phase 2, Phase 3]
Phase 2/3 trial update on vitamin C for septic shock and sepsis; the study has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure [Phase 3]
Phase 3 trial investigating sedation strategies to maximize efficacy and reduce neurological dysfunction and mortality in septic patients wi…
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: Efficacy and Safety of Therapy With IgM-enriched Immunoglobulin With a Personalized Dose vs Standard Dose in Patients With Septic Shock. [Phase 3]
Phase 3 trial evaluating IgM-enriched immunoglobulin with personalized dosing versus standard dosing in septic shock; efficacy and safety ou…
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CLINICAL_TRIALS withdrawal · 2021-05-05Clinical Trial Update: Vitamin D Status in Patients With Severe Sepsis [Phase 3]
A Phase 3 trial assessing vitamin D status in patients with severe sepsis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Early Metabolic Resuscitation for Septic Shock [Phase 2]
Phase 2 trial evaluating early metabolic resuscitation for septic shock was terminated, with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-03-09Clinical Trial Update: The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients [Phase 3]
Phase 3 trial comparing 0.9% sodium chloride to balanced crystalloids for renal function in sepsis patients has completed.
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: The Effect of Remote Ischemic Conditioning on the Microcirculation in Sepsis [Phase 1, Phase 2]
Clinical trial update on remote ischemic conditioning for microcirculation in septic patients (Phase 1/Phase 2) completed.
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Mycobacterium w in Patients With Severe Sepsis [Phase 2, Phase 3]
Clinical trial update for Mycobacterium w in patients with severe sepsis across Phase 2 and Phase 3, completed.
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: High Dose Intravenous Ascorbic Acid in Severe Sepsis [Phase 2]
Phase 2 trial update on high-dose intravenous ascorbic acid in severe sepsis; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Tumescent Anesthesia Antibiotic Delivery (TAAD) [Phase 2, Phase 3]
Phase 2/Phase 3 trial update for a tumescent anesthesia antibiotic delivery approach (TAAD) evaluating surgical site infection and thrombosi…
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial [Phase 2, Phase 3]
Phase 2/Phase 3 trial investigating ascorbic acid, corticosteroids, and thiamine (ACTS) in sepsis and septic shock; study completed with res…
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Triple Therapy in Septic Shock Patients [Phase 3]
A Phase 3 clinical trial evaluating triple therapy in septic shock/sepsis patients has completed recruitment and status is listed as complet…
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS) [Phase 2, Phase 3]
A trial update for the Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS) covering Phase 2 and Phase 3 studies; current status…
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Release of Nociceptin From Granulocytes in Sepsis
Clinical trial update on releasing nociceptin from granulocytes in sepsis; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: The Efficacy of Xuebijing Injection on Sepsis [Phase 4]
Phase 4 clinical trial updating on the efficacy of Xuebijing Injection for sepsis has completed.
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System [Phase 3]
Phase 3 trial update evaluating clarithromycin for severe infections by modulating the immune system in sepsis and pneumonia.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens [Phase 3]
Phase 3 trial evaluating Cefiderocol (S-649266) versus best available therapy for severe infections due to carbapenem-resistant Gram-negativ…
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: Fluid Responsiveness Evaluation in Sepsis-associated Hypotension [NA]
Clinical trial update related to fluid responsiveness evaluation in sepsis-associated hypotension completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Ascorbic Acid and Thiamine Effect in Septic Shock [Phase 2]
Phase 2 clinical trial on the effect of ascorbic acid and thiamine in septic shock/sepsis has completed.
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis [Phase 3]
Phase 3 trial evaluating a vitamin C, thiamine, cyanocobalamine, pyridoxine, and hydrocortisone regimen in sepsis and septic shock has compl…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Vitamin C, Thiamine, and Steroids in Sepsis [Phase 3]
Phase 3 trial update on vitamin C, thiamine, and steroids for sepsis has completed with posted results.
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FDA approval · 2020-09-09FDA Approved: CEFTRIAXONE AND DEXTROSE — Supplemental Application (B. Braun Medical Inc.)
FDA approved a supplemental application for Ceftriaxone and Dextrose from B. Braun Medical, resulting in an updated/expanded approval for th…
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CLINICAL_TRIALS trial_result · 2020-09-09Clinical Trial Update: The Role of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis (NEC) in Pre-term Infants [Phase 2]
A Phase 2 clinical trial evaluating whether Lactobacillus reuteri can prevent necrotizing enterocolitis in pre-term infants, with sepsis as …
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock [Phase 1, Phase 2]
A pharmacokinetic and biomarker study of pioglitazone conducted in adolescents with severe sepsis and septic shock completed Phase 1 and Pha…
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Levels of 'Hypophosphatemia Affect Outcome of Septic Patients in ICU [Phase 4]
A Phase 4 clinical trial evaluating whether hypophosphatemia affects outcomes in septic patients in the ICU is ongoing; current status is un…