Sepsis
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CLINICAL_TRIALS withdrawal · 2016-05-03Clinical Trial Update: Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS) [Phase 2]
A Phase 2 trial evaluating Bevacizumab to prevent acute respiratory distress syndrome in patients with severe sepsis was withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-03-04Clinical Trial Update: Selenium Replacement and Serum Selenium Level in Severe Sepsis and Septic Shock Patients [Phase 2]
Phase 2 clinical trial evaluating selenium replacement in patients with severe sepsis and septic shock has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-10-06Clinical Trial Update: Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome [Phase 1]
This is a Phase 1 trial update for studies of acute lung injury and acute respiratory distress syndrome in the setting of sepsis. The trial …
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CLINICAL_TRIALS withdrawal · 2015-09-02Clinical Trial Update: Procalcitonin Guided Versus Conventional Antibiotic Therapy in Patients With Sepsis in the ICU [NA]
A clinical trial evaluating procalcitonin-guided versus conventional antibiotic therapy in ICU patients with sepsis was withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-07-31Clinical Trial Update: Drugmonitoring of Antiinfective Drugs in Patients Receiving Continous Veno-venous Hemodiafiltration (ABx-CVVHDF)
The ABx-CVVHDF trial examining drug monitoring of anti-infective agents in patients receiving continuous venovenous hemodiafiltration has be…
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CLINICAL_TRIALS withdrawal · 2015-07-21Clinical Trial Update: Multi-marker INDex for the Risk Assessment of Sepsis in the Emergency departmenT (MINDSET)
The MINDSET trial, a multi-marker index for risk assessment of sepsis in the emergency department, sponsored by Abbott RDx Cardiometabolic, …
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CLINICAL_TRIALS withdrawal · 2015-06-18Clinical Trial Update: Different Modes of Temperature Measurement in the Emergency Department [Phase 3]
Phase 3 clinical trial evaluating different modes of temperature measurement in the emergency department for sepsis; the study has been with…
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CLINICAL_TRIALS withdrawal · 2014-10-21Clinical Trial Update: System-level Monitoring of Immune Activation Concerning Susceptibility to Sepsis in Trauma Patients
The clinical trial NCT01472952 investigating system-level immune activation and susceptibility to sepsis in trauma patients has been withdra…
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CLINICAL_TRIALS withdrawal · 2014-05-20Clinical Trial Update: Safety of Heparin in Patients With Septic Shock [Phase 2]
A Phase 2 trial evaluating the safety of heparin in patients with septic shock has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2013-07-19Clinical Trial Update: Determination of the Nature of the Endogenous Ligand of TREM-1 and Its Use as a New Diagnostic Biomarker in Sepsis
The clinical trial evaluating the endogenous ligand of TREM-1 as a diagnostic biomarker for sepsis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2013-01-16Clinical Trial Update: Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability
A Duke University-sponsored clinical trial evaluating maternal-infant therapeutics for safety, mortality, and disability has been withdrawn;…
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CLINICAL_TRIALS withdrawal · 2012-11-14Clinical Trial Update: Pharmacokinetics and Safety of Ticarcillin-clavulanate in Infants [Phase 1]
A Phase 1 study evaluating the pharmacokinetics and safety of ticarcillin-clavulanate in infants for sepsis has been withdrawn.
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EMA withdrawal · 2012-02-21EMA Withdrawn: Xigris (drotrecogin alfa (activated)) — Eli Lilly Nederland B.V.
The EMA withdrew Xigris (drotrecogin alfa activated) from the market for sepsis with multiple organ failure.
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CLINICAL_TRIALS withdrawal · 2012-02-13Clinical Trial Update: Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis [Phase 4]
This Phase 4 clinical trial comparing hydrocortisone alone versus hydrocortisone plus fludrocortisone for adrenal insufficiency in severe se…
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EMA withdrawal · 2011-10-25Xigris (drotrecogin alfa (activated)) to be withdrawn due to lack of efficacy
The EMA announces the withdrawal of Xigris (drotrecogin alfa activated) from the market due to lack of efficacy.
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CLINICAL_TRIALS withdrawal · 2011-08-04Clinical Trial Update: Impact of Clinical, Demographic and Laboratory Variables on Brain Natriuretic Peptide Levels
The trial evaluating factors that influence brain natriuretic peptide levels in patients with sepsis or heart failure has been withdrawn fro…
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CLINICAL_TRIALS withdrawal · 2011-03-01Clinical Trial Update: Arterial Blood Pressure-complexity in Septic Patients
The study on arterial blood pressure complexity in septic patients has been suspended.
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CLINICAL_TRIALS withdrawal · 2008-05-29Clinical Trial Update: Methylene Blue in Sepsis: A Randomized Controlled Trial [NA]
A randomized controlled trial evaluating methylene blue for sepsis has been withdrawn. This update confirms the study status as withdrawn.