Sepsis
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Sensitivity and Specificity of Leucocytes Profiling Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial
An observational multicenter trial evaluating the sensitivity and specificity of leucocyte profiling versus platelet indices to predict clin…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Respiratory Variations for Predicting Fluid Responsiveness [NA]
This clinical trial update from University Hospital, Lille reports completion of a study on respiratory variations for predicting fluid resp…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Alpha-lipoic Acid in Critically Ill Patients With Sepsis [NA]
A completed clinical trial from Damanhour University evaluating alpha-lipoic acid in critically ill patients with sepsis.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Study of Protection And Repair of Endothelial-glycocalyx in Sepsis (SPARES) [Phase 2]
SPARES is a Phase 2 trial evaluating protection and repair of the endothelial glycocalyx in sepsis. The study status is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) [Phase 4]
Phase 4 clinical trial evaluating paramedic-initiated treatment for severe sepsis or septic shock in out-of-hospital patients has completed.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Clinical Efficacy of Megadose Vitamin C in Sepsis [Phase 2]
A Phase 2 trial evaluating the clinical efficacy of megadose vitamin C in patients with sepsis and septic shock has completed.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Risk Factors, Costs, and Impacts of ED Boarding
A completed clinical trial update from the University of Maryland examines risk factors, costs, and impacts of emergency department boarding…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS [Phase 3]
Phase 3 trial evaluating GM-CSF to reverse immunoparalysis in pediatric sepsis-induced MODS has completed.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Biomarkers for Predicting Mortality in Patients With Suspected Sepsis
This is a completed clinical trial assessing biomarkers to predict mortality in patients with suspected sepsis. The study aims to identify b…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Point of Care Evaluation of Fibrinolysis in Sepsis [NA]
A completed study evaluating fibrinolysis at the point of care in sepsis, focusing on fibrinolytic defects in critically ill patients.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Nafamostat Mesylate Versus Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy in Sepsis-Associated Acute Kidney Injury [Phase 4]
A Phase 4 trial is comparing nafamostat mesylate to regional citrate anticoagulation for continuous renal replacement therapy in sepsis-asso…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Role of the Kallikrein-kinin System in Septic Cardiomyopathy
This completed clinical trial explored the role of the kallikrein-kinin system in septic cardiomyopathy in patients with sepsis.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Prognostic Interest of Vasorin in Septic Shock [NA]
A completed clinical trial evaluating the prognostic value of vasorin in septic shock, involving sepsis and acute kidney injury as condition…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: National Study on Listeriosis and Listeria
A national study on Listeriosis and Listeria has completed, focusing on infections and related pregnancy complications.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Systemic Immune-Inflamation Index and Mortality in ICU Patients
The registry entry summarizes a completed study from Ataturk University examining the Systemic Immune-Inflammation Index and mortality in IC…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or Without Sepsis/ARDS) [Phase 2]
Phase 2 trial evaluating nogapendekin alfa-inbakicept in combination with iNKT cell therapy for critically ill adults with severe community-…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Precision Resuscitation With Crystalloids in Sepsis [NA]
A clinical trial sponsored by Emory University testing precision resuscitation with crystalloids in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Home-based Digital Exercise Training Program to Improve Physical Function of Older Sepsis Survivors - HEAL Sepsis Trial [NA]
The HEAL Sepsis Trial evaluated a home-based digital exercise training program to improve physical function in older sepsis survivors. The s…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Role of Enteral Lactoferrin as an Adjuvant for Prevention of Sepsis Among Preterm Neonates [Phase 1]
Phase 1 trial evaluating enteral lactoferrin as an adjuvant to prevent sepsis in preterm neonates has completed.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Study Looking at the Use of Biomarkers to Provide Early Indication of Acute Kidney Injury in Patients With Sepsis (Limiting AKI Progression In Sepsis) [NA]
BioMérieux's biomarker study to provide early indication of acute kidney injury in sepsis patients has been terminated. The study did not pr…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis [Phase 3]
A Phase 3 pediatric trial comparing balanced crystalloids versus normal saline for sepsis has completed.
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants [Phase 2]
A Phase 2 study assessing safety, tolerability, and pharmacokinetics of cefiderocol in hospitalized pediatric participants has completed wit…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Fluids in Septic Shock (FISSH) [Phase 2, Phase 3]
The Fluids in Septic Shock (FISSH) trial, spanning Phase 2 and Phase 3, has completed its studies. It investigates fluid therapy options for…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Effect of Direct-from-blood Bacterial Testing on Antibiotic Administration and Clinical Outcomes [NA]
This clinical trial investigates whether direct-from-blood bacterial testing changes antibiotic prescribing and patient outcomes in bloodstr…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group [NA]
A completed clinical trial comparing plasma neutrophil gelatinase-associated lipocalin (pNGAL) levels in de-resuscitation with furosemide ve…