Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2008-05-14Clinical Trial Update: Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment With Corticosteroids
A completed clinical trial update examining the time course of procalcitonin and C-reactive protein in septic patients treated with corticos…
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CLINICAL_TRIALS trial_result · 2008-05-09Clinical Trial Update: Cortisol Control of Human Inflammatory Responses to Endotoxin [NA]
The trial evaluating cortisol's ability to regulate inflammatory responses to endotoxin in sepsis has completed. No results are provided in …
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CLINICAL_TRIALS trial_result · 2008-03-13Clinical Trial Update: Enteral Glutamine in Critical Illness [Phase 2, Phase 3]
The clinical trial update indicates that phase 2 and phase 3 studies of enteral glutamine in critical illness, including sepsis, have been t…
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CLINICAL_TRIALS trial_result · 2008-02-15Clinical Trial Update: Lactulose Supplementation in Premature Infants [Phase 2]
This Phase 2 clinical trial evaluating lactulose supplementation in premature infants has completed. The study targeted necrotizing enteroco…
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CLINICAL_TRIALS trial_result · 2008-02-07Clinical Trial Update: Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen [Phase 4]
Phase 4 trial comparing cefepime continuous infusion with intermittent dosing for sepsis and bacteremia has completed.
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CLINICAL_TRIALS trial_result · 2008-01-24Clinical Trial Update: A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status
A Mayo Clinic-led trial completed, evaluating a simple clinical tool to assess fluid status in patients with sepsis.
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CLINICAL_TRIALS trial_result · 2008-01-15Clinical Trial Update: Unfractioned Heparin for Treatment of Sepsis [Phase 3]
A Phase 3 clinical trial evaluating unfractionated heparin for the treatment of sepsis has completed. Sponsored by Universidad de Antioquia,…
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CLINICAL_TRIALS trial_result · 2007-12-11Clinical Trial Update: Oxytocin Effects on Cytokines and Endocrine Parameters After LPS Induced Systemic Inflammatory Effects in Healthy Volunteers
This completed early-phase clinical trial evaluated the effects of oxytocin on cytokines and endocrine parameters after LPS-induced systemic…
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CLINICAL_TRIALS trial_result · 2007-12-07Clinical Trial Update: A Safety Evaluation of Drotrecogin Alfa (Activated) in Patients With Blood Cancer, Severe Infection Related to Bone Marrow Transplantation [Phase 4]
Phase 4 safety evaluation of drotrecogin alfa activated in patients with sepsis related to hematologic neoplasms and bone marrow transplanta…
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CLINICAL_TRIALS trial_result · 2007-12-06Clinical Trial Update: The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death [Phase 3]
A Phase 3 clinical trial evaluating drotrecogin alfa (activated) in adults with severe sepsis at low risk of death has been completed. The s…
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CLINICAL_TRIALS trial_result · 2007-12-06Clinical Trial Update: An Open Label Study of Severe Sepsis in Adults [Phase 4]
An open-label Phase 4 study of a treatment for Severe Sepsis in adults has completed.
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CLINICAL_TRIALS trial_result · 2007-11-20Clinical Trial Update: Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis [Phase 3]
A Phase 3 pediatric trial evaluating the efficacy and safety of drotrecogin alfa (activated) for severe sepsis has completed.
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CLINICAL_TRIALS trial_result · 2007-10-23Clinical Trial Update: Combination Therapy With Fluoroquinolone in Staphylococcus Aureus Bacteremia
A completed clinical trial evaluating combination therapy with a fluoroquinolone for Staphylococcus aureus bacteremia.
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CLINICAL_TRIALS trial_result · 2007-10-12Clinical Trial Update: Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion [Phase 3]
This Phase 3 trial compares 4-day versus 7-day infusion durations of drotrecogin alfa activated in sepsis and the study has completed.
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CLINICAL_TRIALS trial_result · 2007-09-27Clinical Trial Update: The Utility of Ischemia Modified Albumin (IMA) in Sepsis
A completed clinical trial evaluating ischemia-modified albumin as a biomarker for sepsis.
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CLINICAL_TRIALS trial_result · 2007-09-05Clinical Trial Update: IL 6 Measurement Using a New Densitometric Bedside (POC) Test
A completed clinical trial evaluated a new densitometric bedside point-of-care test for measuring interleukin-6 in patients with sepsis and …
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CLINICAL_TRIALS trial_result · 2007-06-06Clinical Trial Update: Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients
This clinical trial update reports on an investigation evaluating the relationship between interstitial and arterial blood glucose levels in…
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CLINICAL_TRIALS trial_result · 2007-04-06Clinical Trial Update: Effects of Alkaline Phosphatase on Renal Function in Septic Patients [Phase 2]
This clinical trial update reports on a Phase 2 study evaluating the effect of alkaline phosphatase on renal function in septic patients, an…
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CLINICAL_TRIALS trial_result · 2007-03-21Clinical Trial Update: Pharmacokinetic of Ceftriaxone in Septic ICU Patients [Phase 4]
Phase 4 pharmacokinetic study of ceftriaxone in septic ICU patients, providing data on how the drug behaves in critically ill individuals.
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CLINICAL_TRIALS trial_result · 2007-01-26Clinical Trial Update: A Trial of Heparin in Patients With Severe Sepsis Who Are Undergoing Treatment With Drotrecogin Alfa (Activated) [Phase 4]
This completed Phase 4 trial evaluated adding heparin to drotrecogin alfa (activated) therapy in severe sepsis. The study aimed to assess sa…
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CLINICAL_TRIALS trial_result · 2006-12-27Clinical Trial Update: Super High-Flux - High Volume Dialysis in Sepsis-Induced Acute Renal Failure [Phase 1, Phase 2]
The document reports the completion of a Phase 1/2 clinical trial evaluating super high-flux, high-volume dialysis in sepsis-induced acute k…
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CLINICAL_TRIALS trial_result · 2006-12-05Clinical Trial Update: Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring [NA]
The pediatric septic shock treatment trial comparing care with versus without central venous oxygen saturation monitoring has completed.
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CLINICAL_TRIALS trial_result · 2006-12-04Clinical Trial Update: Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis [Phase 4]
A Phase 4 clinical trial assessed whether continuous venovenous haemofiltration influences organ failure in the early stages of severe sepsi…
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CLINICAL_TRIALS trial_result · 2006-09-11Clinical Trial Update: Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants [Phase 3]
Reports a Phase 3 efficacy trial of community-based treatment for serious bacterial infections in newborns; current trial status is unknown.
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CLINICAL_TRIALS trial_result · 2006-09-11Clinical Trial Update: The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients [Phase 4]
Phase 4 trial evaluating whether adding fish oil to nutrition improves outcomes in critically ill patients with sepsis. The study status is …