Sepsis
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CLINICAL_TRIALS trial_result · 2011-05-18Clinical Trial Update: Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation [Phase 2]
Phase 2 study evaluating ART-123 for safety and efficacy in sepsis with disseminated intravascular coagulation has completed.
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CLINICAL_TRIALS trial_result · 2011-04-11Clinical Trial Update: Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis
A completed clinical trial evaluating the impact of hydrocortisone on white blood cell gene expression in patients with severe sepsis and re…
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CLINICAL_TRIALS trial_result · 2011-04-11Clinical Trial Update: Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis
This completed clinical trial studied microcirculatory changes during magnesium sulfate infusion in patients with sepsis, including severe s…
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CLINICAL_TRIALS trial_result · 2011-04-05Clinical Trial Update: The Effects of HIV Protease Inhibitors in Severe Sepsis [Phase 1]
A Phase 1 trial conducted by Mayo Clinic evaluated the effects of HIV protease inhibitors in patients with severe sepsis. The study status i…
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CLINICAL_TRIALS trial_result · 2011-03-09Clinical Trial Update: Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock [Phase 4]
A Phase 4 clinical trial evaluated strategies to improve tissue oxygenation with the goal of reducing mortality in severe sepsis and septic …
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CLINICAL_TRIALS trial_result · 2011-03-02Clinical Trial Update: Paracetamol Toxicity in Septic Patients [Phase 3]
A Phase 3 study evaluating paracetamol toxicity in septic patients has been suspended.
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CLINICAL_TRIALS trial_result · 2011-02-21Clinical Trial Update: Effect of Rosuvastatin in Abdominal Sepsis [Phase 2]
A Phase 2 clinical trial is evaluating the effect of rosuvastatin in abdominal sepsis; the current status of the study is unknown.
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CLINICAL_TRIALS trial_result · 2011-01-12Clinical Trial Update: The Effect of Moderate-Dose Steroid Therapy in Sepsis [Phase 4]
This document reports the completion of a Phase 4 clinical trial assessing moderate-dose corticosteroid therapy in patients with sepsis.
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CLINICAL_TRIALS trial_result · 2010-12-16Clinical Trial Update: Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated) [Phase 2]
A Phase 2 clinical trial evaluating protein C levels in severe sepsis patients treated with drotrecogin alfa (activated) has completed, with…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: Therapeutic Zinc in Infant Bacterial Illness [Phase 2, Phase 3]
Update on Phase 2 and Phase 3 trials evaluating zinc as a therapeutic for infant bacterial illnesses, including sepsis and pneumonia, with c…
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CLINICAL_TRIALS trial_result · 2010-12-06Clinical Trial Update: Study of Procalcitonin (PCT)-Guided Antibiotic Use in Severe Sepsis Patients Without Obvious Infection [Phase 4]
Phase 4 clinical trial update indicates the study evaluating procalcitonin-guided antibiotic use in severe sepsis patients without obvious i…
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CLINICAL_TRIALS trial_result · 2010-12-01Clinical Trial Update: Effect of the Intensity of Continuous Renal Replacement Therapy [NA]
A completed clinical trial evaluated the effects of different intensities of continuous renal replacement therapy on patients with sepsis.
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CLINICAL_TRIALS trial_result · 2010-11-29Clinical Trial Update: Pro-inflammatory Cytokines Profile and Mortality Rate of Critically Ill Septic Patients Following Plasmapheresis [NA]
This document provides an update on a clinical trial evaluating pro-inflammatory cytokines and mortality in critically ill septic patients t…
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CLINICAL_TRIALS trial_result · 2010-11-05Clinical Trial Update: Anti-inflammatory Effects of GTS-21 After LPS [NA]
A completed trial evaluated the anti-inflammatory effects of the alpha7 nicotinic receptor agonist GTS-21 after LPS exposure in endotoxemia …
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CLINICAL_TRIALS trial_result · 2010-10-07Clinical Trial Update: Procalcitonin Monitoring May Decrease Antibiotic Use in the Intensive Care Unit
A University of Athens-sponsored clinical trial update suggests monitoring procalcitonin levels may reduce antibiotic use in ICU patients wi…
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CLINICAL_TRIALS trial_result · 2010-09-03Clinical Trial Update: L-citrulline Supplementation During Sepsis [Phase 3]
Phase 3 trial of L-citrulline supplementation for sepsis is in progress; the study status is unknown.
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CLINICAL_TRIALS trial_result · 2010-09-02Clinical Trial Update: Cytokine Removal by CRRT in Pediatric Sepsis [NA]
A completed clinical trial evaluating cytokine removal by continuous renal replacement therapy in pediatric sepsis.
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CLINICAL_TRIALS trial_result · 2010-07-22Clinical Trial Update: A Study in Critically Ill Patients Investigating Tolerability and Efficacy of Low-volume Pharmaconutrition (Intestamin) [NA]
Completed clinical trial evaluating tolerability and efficacy of low-volume pharmaconutrition (Intestamin) in critically ill adult patients,…
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CLINICAL_TRIALS trial_result · 2010-07-22Clinical Trial Update: Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock [Phase 2, Phase 3]
Phase 2/3 trial comparing norepinephrine plus dobutamine versus epinephrine alone for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2010-07-14Clinical Trial Update: PD-1/PD-L1 Pathway Study on Septic Patients
A completed clinical trial evaluated modulation of the PD-1/PD-L1 pathway in septic patients.
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CLINICAL_TRIALS trial_result · 2010-07-09Clinical Trial Update: Benefit of SeptiFast Multiplex PCR in the Etiologic Diagnosis and Therapeutic Approach for Onco-hematology Patients Presenting Sepsis
A completed trial evaluated the use of SeptiFast multiplex PCR to identify the cause of sepsis in patients with hematologic diseases and to …
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CLINICAL_TRIALS trial_result · 2010-07-07Clinical Trial Update: A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult [NA]
A randomized trial evaluating the safety and efficacy of GR270774 for Gram-negative sepsis in adults has been suspended.
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CLINICAL_TRIALS trial_result · 2010-06-04Clinical Trial Update: The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial [Phase 3]
A Phase 3 randomized trial evaluated whether Polymyxin B protects against sepsis-induced kidney dysfunction; results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-05-31Clinical Trial Update: Neutrophile Gelatinase Associated Lipocalin Evaluation in Septic Acute Kidney Injury
A clinical trial update examining neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in septic acute kidney injury.
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CLINICAL_TRIALS trial_result · 2010-04-14Clinical Trial Update: Fluid Resuscitation in Early Septic Shock [Phase 2]
This is a Phase 2 trial update on fluid resuscitation for early septic shock, with the study status showing as completed.