Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: Extracardiac Complications After Cardiac Surgery
A completed clinical trial from the University of Turin assessing extracardiac complications after cardiac surgery, including Acute Lung Inj…
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU
A completed clinical trial evaluating a hematological infection score versus the hospital standard for diagnosing systemic inflammatory resp…
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CLINICAL_TRIALS trial_result · 2011-12-29Clinical Trial Update: Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections [Phase 4]
A Phase 4 trial evaluated diagnosing septicaemia in severe infections by detecting microbial DNA in blood, involving febrile neutropenia, en…
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CLINICAL_TRIALS trial_result · 2011-12-19Clinical Trial Update: Procalcitonin as a Tool to Shorten Antibiotic Therapy in the ICU [NA]
A completed ICU trial evaluated using procalcitonin levels to guide shortening antibiotic therapy in sepsis and reported whether this approa…
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CLINICAL_TRIALS trial_result · 2011-12-13Clinical Trial Update: TREM-1 Gene Polymorphisms
This document reports the completion of a clinical trial studying TREM-1 gene polymorphisms in patients with sepsis. The sponsor listed is t…
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CLINICAL_TRIALS trial_result · 2011-11-24Clinical Trial Update: The Effects of Linezolid and Vancomycin on Inflammation and Cellular Signaling Vents
A completed clinical trial update examining the effects of linezolid and vancomycin on inflammation and cellular signaling in sepsis. The st…
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CLINICAL_TRIALS trial_result · 2011-10-27Clinical Trial Update: Colombia Epidemiologic Surveillance Study
Pfizer-sponsored Colombia Epidemiologic Surveillance Study has been terminated. The study investigated Pneumonia, Meningitis, Bacteremia, an…
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CLINICAL_TRIALS trial_result · 2011-10-06Clinical Trial Update: Indocyanine Clearance Rate and Septic Liver Injury
A clinical trial update from Sun Yat-sen University investigates indocyanine clearance rate in septic liver injury during sepsis. The curren…
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CLINICAL_TRIALS trial_result · 2011-09-15Clinical Trial Update: Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease [Phase 3]
A Phase 3 trial evaluating daily zinc supplementation in low birth weight infants has completed, examining its impact on death and severe il…
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CLINICAL_TRIALS trial_result · 2011-09-14Clinical Trial Update: Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients [NA]
The trial evaluated whether a predictive proteic profile could predict mortality in the acute phase of septic shock among cancer patients. T…
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CLINICAL_TRIALS trial_result · 2011-08-23Clinical Trial Update: Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis [Phase 2]
This document reports the completion of a Phase 2 safety and efficacy study evaluating recombinant human lactoferrin for severe sepsis, spon…
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CLINICAL_TRIALS trial_result · 2011-08-12Clinical Trial Update: BaSES Trial: Basel Starch Evaluation in Sepsis [Phase 4]
Phase 4 trial evaluating hydroxyethyl starch for sepsis has completed (BaSES trial).
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO
This completed clinical trial evaluated whether the biomarkers sTREM-1, procalcitonin (PCT), and C-reactive protein (CRP) can detect sepsis …
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Clarithromycin as Immunomodulator for the Management of Sepsis [Phase 3]
Phase 3 trial evaluating clarithromycin as an immunomodulator for sepsis (including severe sepsis and septic shock) has completed.
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Lipid Profile in Patients With Severe Sepsis or Septic Shock Under Strict or Liberal Glycemic Control [NA]
An update on a completed clinical trial evaluated lipid profiles in patients with severe sepsis or septic shock under strict versus liberal …
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries
A completed clinical trial investigating soluble TREM-1 in sepsis and related acute kidney injury conditions; no results are described in th…
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis [Phase 3]
A Phase 3 trial evaluated Voluven for its effects on hemodynamics and tolerability of enteral nutrition in patients with severe sepsis, with…
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CLINICAL_TRIALS trial_result · 2011-08-01Clinical Trial Update: Diagnostic Value of sTREM-1 and PCT Level as Well as CPIS Score for Ventilator-Associated Pneumonia Among ICU Sepsis Patients
This clinical trial update reports an evaluation of sTREM-1 and procalcitonin levels, along with the CPIS score, for diagnosing ventilator-a…
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Renal Impairment Associated With Colistin Levels
A completed clinical trial update notes that higher colistin exposure is associated with renal impairment, highlighting a safety considerati…
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CLINICAL_TRIALS trial_result · 2011-07-11Clinical Trial Update: The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation [Phase 4]
A completed Phase 4 trial from the Medical University of Vienna evaluated the role of the P2Y12 receptor in tissue factor–induced coagulatio…
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CLINICAL_TRIALS trial_result · 2011-06-21Clinical Trial Update: Outcome Predictors in Patients With Severe Sepsis and Optimized Central Venous Oxygen Saturation
A completed clinical trial evaluating predictors of outcomes in patients with severe sepsis treated to optimize central venous oxygen satura…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity [Phase 3]
Phase 3 clinical trial evaluating probiotics to prevent preterm birth and related neonatal morbidity was terminated.
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CLINICAL_TRIALS trial_result · 2011-06-14Clinical Trial Update: Efficacy of Thymosin alpha1 for Severe Sepsis [NA]
The clinical trial evaluating thymosin alpha-1 for severe sepsis has completed; the update does not report efficacy results.
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CLINICAL_TRIALS trial_result · 2011-06-07Clinical Trial Update: Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis [NA]
A completed clinical trial evaluating the CytoSorb hemoperfusion device for removing interleukin-6 in patients with acute respiratory distre…
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CLINICAL_TRIALS trial_result · 2011-05-26Clinical Trial Update: Reconstruction of Monocytic Immunocompetence by Granulocyte-macrophage-colony Stimulating Factor (GM-CSF) in Patients With Severe Sepsis and Septic Shock [Phase 2]
Phase 2 clinical trial evaluating whether granulocyte-macrophage colony-stimulating factor (GM-CSF) can restore monocytic immune competence …