Sepsis
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: The Value of PSP in Predicting Outcome in ICU Surgical Peritonitis Patients
This clinical trial update assesses whether the biomarker PSP can predict outcomes in ICU patients with surgical peritonitis.
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Investigate the Activity of Endotoxin in Severe Sepsis
A National Taiwan University Hospital trial examining endotoxin activity in severe sepsis and septic shock has been terminated.
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II [Phase 3]
Phase 3 study evaluating the in vivo effects of C1-esterase inhibitor on the innate immune response during endotoxemia; the trial status is …
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CLINICAL_TRIALS trial_result · 2014-11-24Clinical Trial Update: Urinary Heparanase Activity as a Predictor of Acute Kidney Injury in Critically Ill Adults
A completed clinical trial evaluating urinary heparanase activity as a predictor of acute kidney injury in critically ill adults with sepsis…
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CLINICAL_TRIALS trial_result · 2014-11-20Clinical Trial Update: The Prevention of Failure to Rescue Using Early Warning Scoring
Trial NCT01197326 evaluating early warning scoring to prevent failure to rescue has completed and posted results. Sponsored by Philips Healt…
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CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis [Phase 2]
Phase 2 randomized trial comparing calcitriol to placebo in critically ill patients with sepsis has completed and results were posted in 201…
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CLINICAL_TRIALS trial_result · 2014-10-21Clinical Trial Update: Immune Activation, Hypoxia and Vasoreaction in Sepsis of Pulmonary Versus Abdominal Origin
Completed clinical trial assessing immune activation, hypoxia, and vasoreaction in sepsis of pulmonary versus abdominal origin; the update n…
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CLINICAL_TRIALS trial_result · 2014-10-17Clinical Trial Update: Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock [Phase 3]
Phase 3 clinical trial assessing stress-dose hydrocortisone for coagulation dysfunction in septic shock has completed.
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CLINICAL_TRIALS trial_result · 2014-10-17Clinical Trial Update: Transluminal or Percutaneous Endoscopic Drainage and Debridement of Abcesses After Bariatric Surgery
Update on a completed clinical trial evaluating transluminal or percutaneous endoscopic drainage and debridement of abscesses after bariatri…
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates [NA]
A clinical trial assessing ethanol locking to prevent central line infections in premature neonates was terminated.
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Statins for Acutely Injured Lungs From Sepsis [Phase 3]
A Phase 3 trial evaluating statins for sepsis-associated acute lung injury was terminated, and the results have been posted.
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Simplified Antibiotic Regimens for Outpatient Treatment of Suspected Sepsis in Neonates and Young Infants in Bangladesh [NA]
A completed clinical trial in Bangladesh evaluating simplified outpatient antibiotic regimens for suspected sepsis in neonates and young inf…
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: Indicators of Inflammation and Coagulation in Sepsis
This entry notes that a clinical trial investigating markers of inflammation and coagulation in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2014-09-09Clinical Trial Update: Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients [NA]
A completed clinical trial evaluating glutamine and antioxidant supplementation in critically ill patients, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Chlorhexidine Vaginal and Infant Wash in Pakistan [Phase 3]
Clinical Trial Update indicating the Phase 3 trial of chlorhexidine vaginal and infant wash in Pakistan has completed.
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Prevention of Infection in Indian Neonates - Phase I Observational Study
Phase I observational trial evaluating infection prevention in Indian neonates has completed, with sepsis as the primary focus.
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CLINICAL_TRIALS trial_result · 2014-07-16Clinical Trial Update: Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock [Phase 2, Phase 3]
A clinical trial update on tigecycline for severe sepsis and septic shock (Phase 2/Phase 3) with abdominal infection as a condition; the cur…
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis [Phase 3]
Phase 3 trial assessing the impact of low-dose unfractionated heparin on inflammation in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2014-07-01Clinical Trial Update: Ascorbic Acid (Vitamin C) Infusion in Human Sepsis [Phase 1, Phase 2]
Phase 1/2 clinical trial of ascorbic acid infusion in humans with sepsis/septic shock has been completed with posted results.
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CLINICAL_TRIALS trial_result · 2014-06-25Clinical Trial Update: Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock [Phase 4]
Phase 4 trial comparing Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) to Early Goal-Directed Therapy (EGDT) in septic s…
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Outcomes of Severe Sepsis Patients in Surgical Intensive Care Units
A completed clinical trial conducted by National Taiwan University Hospital evaluating outcomes for severe sepsis and septic shock patients …
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CLINICAL_TRIALS trial_result · 2014-05-23Clinical Trial Update: Sepsis Pathophysiological & Organisational Timing
This clinical trial update reports on a completed study investigating the pathophysiology of sepsis and the impact of timing on organisation…
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: Experimental Determination of Atot en Ka in the Critically Ill
Completed clinical trial assessing pharmacokinetic parameters Atot and Ka in critically ill patients with sepsis or undergoing CABG.
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: Albumin Administration in Cirrhotic Patients With Bacterial Infection and a Systemic Inflammatory Response Syndrome Unrelated to Spontaneous Bacterial Peritonitis [Phase 3]
A Phase 3 trial evaluating albumin administration in cirrhotic patients with bacterial infection and a systemic inflammatory response syndro…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: The Effect of Ketanserin on the Microcirculation in Sepsis [Phase 3]
A Phase 3 clinical trial evaluating ketanserin's effect on microcirculation in patients with sepsis has completed.