Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-02-24Clinical Trial Update: Antibiotic/COPD in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Requiring Mechanical Ventilation [Phase 3]
Phase 3 trial in COPD patients with acute exacerbation requiring mechanical ventilation evaluated an antibiotic regimen; study completed.
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CLINICAL_TRIALS trial_result · 2020-02-21Clinical Trial Update: Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis. [Phase 4]
Phase 4 trial update evaluating the efficacy and safety of Rheosorbilact® Solution for infusion as part of complex therapy for sepsis.
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Evaluating Muscle Weakness Improvement With Lorcaserin in ICU [Phase 1, Phase 2]
A phase 1/2 trial evaluating lorcaserin for muscle weakness in ICU patients with sepsis was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2019-12-06Clinical Trial Update: Vitamin C, Vitamin B1 and Steroid in Sepsis [Phase 4]
Phase 4 clinical trial update investigating the use of vitamin C, vitamin B1, and a steroid for sepsis and severe sepsis.
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CLINICAL_TRIALS trial_result · 2019-11-01Clinical Trial Update: A Randomized Controlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study) [NA]
A randomized controlled trial evaluating a conservative fluid balance strategy in patients with sepsis and cardiopulmonary dysfunction; stud…
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CLINICAL_TRIALS trial_result · 2019-10-28Clinical Trial Update: Antibiotic Prophylaxis in Patients Undergoing GVO [Phase 4]
Phase 4 clinical trial updating antibiotic prophylaxis for patients undergoing GVO (gastric variceal obliteration) with conditions including…
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CLINICAL_TRIALS trial_result · 2019-10-15Clinical Trial Update: Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury [Phase 2]
Phase 2 trial update for vitamin C infusion in sepsis-induced acute lung injury has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial [Phase 2]
Phase 2 trial update for a vitamin C, hydrocortisone, and thiamine regimen in septic shock patients; study completed.
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: Rapid Atrial Fibrillation Treatment Strategy [Phase 4]
Phase 4 clinical trial update investigating a rapid treatment strategy for new-onset atrial fibrillation in hospitalized patients, including…
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CLINICAL_TRIALS trial_result · 2019-08-05Clinical Trial Update: Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study [Phase 1]
A Phase 1 pilot feasibility trial comparing balanced versus normal saline fluids for pediatric sepsis conducted, completed with results post…
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CLINICAL_TRIALS trial_result · 2019-07-08Clinical Trial Update: Effect of Different Electric Muscle Stimulation in Patients With Severe Sepsis and Respiratory Failure [NA]
Clinical trial investigating different electric muscle stimulation in patients with severe sepsis and respiratory failure; study terminated …
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CLINICAL_TRIALS trial_result · 2019-05-03Clinical Trial Update: Zambia Chlorhexidine Application Trial [Phase 2, Phase 3]
Phase 2/3 clinical trial investigating chlorhexidine application for sepsis has completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-04Clinical Trial Update: Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis [Phase 4]
Phase 4 clinical trial evaluating thymosin alpha-1 for improving monocyte function in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2019-04-04Clinical Trial Update: A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock. [Phase 1]
Phase 1 trial evaluating safety and pharmacokinetics of nivolumab in patients with severe sepsis or septic shock; study completed with resul…
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CLINICAL_TRIALS trial_result · 2019-04-02Clinical Trial Update: Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic Shock [Phase 4]
Phase 4 trial update on using amiodarone for atrial fibrillation in patients with severe sepsis or septic shock; the study is terminated wit…
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CLINICAL_TRIALS trial_result · 2019-03-15Clinical Trial Update: Effects of Fat-soluble Vitamins Supplementation on Common Complications and Neural Development in Very Low Birth Weight Infants [Phase 3]
Phase 3 trial evaluating fat-soluble vitamin supplementation effects on complications and neural development in very low birth weight infant…
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CLINICAL_TRIALS trial_result · 2019-03-04Clinical Trial Update: The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis [Phase 4]
Phase 4 clinical trial investigating the effect of Dexmedetomidine on microcirculation in severe sepsis; the study was terminated.
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CLINICAL_TRIALS trial_result · 2019-02-22Clinical Trial Update: Efficacy and Safety Study of CA330 Hemoadsorption Device on IL-6 Removal in Septic Patients [NA]
This entry provides an update on a clinical trial evaluating the CA330 Hemoadsorption Device for IL-6 removal in septic patients, focusing o…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock [Phase 4]
A Phase 4 terminated clinical trial evaluating whether the combination of vitamin C, thiamine, and hydrocortisone affects the clinical cours…
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Novel Device for Rapid Fluid Administration [NA]
A completed Yale University clinical trial evaluated a novel device for rapid fluid administration in sepsis, with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: Following of Myeloid-derived Suppressor Cells (MDSC) in Severe Sepsis: What Relationship With Systemic Inflammatory Syndrome?
The clinical trial investigating myeloid-derived suppressor cells in severe sepsis and their relationship to systemic inflammatory syndrome …
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CLINICAL_TRIALS trial_result · 2019-01-22Clinical Trial Update: Feeding Bovine Colostrum to Preterm Infants [NA]
A completed clinical trial evaluated feeding bovine colostrum in preterm infants with outcomes including feeding intolerance and extrauterin…
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CLINICAL_TRIALS trial_result · 2019-01-03Clinical Trial Update: Changes in Exhaled 13CO2/12CO2 Breath Delta Value as an Early Indicator of Infection in ICU Patients [NA]
Clinical trial update on exhaled 13CO2/12CO2 breath delta as an early indicator of infection in ICU patients with sepsis; study status compl…
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CLINICAL_TRIALS trial_result · 2018-10-23Clinical Trial Update: Control Versus Liberal Cardiac Frequency in Patients in Sepse With Atrial Fibrillation of High Ventricular Response [Phase 3]
Phase 3 clinical trial comparing control versus liberal heart rate strategies in septic patients with atrial fibrillation and high ventricul…
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CLINICAL_TRIALS trial_result · 2018-10-12Clinical Trial Update: S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRT [NA]
Clinical trial update indicating termination of the S.A.F.E.BT System Extracorporeal Treatment with DIAPACT CRRT in severe sepsis; results p…