Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Tumescent Anesthesia Antibiotic Delivery (TAAD) [Phase 2, Phase 3]
Phase 2/Phase 3 trial update for a tumescent anesthesia antibiotic delivery approach (TAAD) evaluating surgical site infection and thrombosi…
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial [Phase 2, Phase 3]
Phase 2/Phase 3 trial investigating ascorbic acid, corticosteroids, and thiamine (ACTS) in sepsis and septic shock; study completed with res…
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Triple Therapy in Septic Shock Patients [Phase 3]
A Phase 3 clinical trial evaluating triple therapy in septic shock/sepsis patients has completed recruitment and status is listed as complet…
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS) [Phase 2, Phase 3]
A trial update for the Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS) covering Phase 2 and Phase 3 studies; current status…
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Release of Nociceptin From Granulocytes in Sepsis
Clinical trial update on releasing nociceptin from granulocytes in sepsis; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: The Efficacy of Xuebijing Injection on Sepsis [Phase 4]
Phase 4 clinical trial updating on the efficacy of Xuebijing Injection for sepsis has completed.
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System [Phase 3]
Phase 3 trial update evaluating clarithromycin for severe infections by modulating the immune system in sepsis and pneumonia.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens [Phase 3]
Phase 3 trial evaluating Cefiderocol (S-649266) versus best available therapy for severe infections due to carbapenem-resistant Gram-negativ…
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: Fluid Responsiveness Evaluation in Sepsis-associated Hypotension [NA]
Clinical trial update related to fluid responsiveness evaluation in sepsis-associated hypotension completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Ascorbic Acid and Thiamine Effect in Septic Shock [Phase 2]
Phase 2 clinical trial on the effect of ascorbic acid and thiamine in septic shock/sepsis has completed.
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis [Phase 3]
Phase 3 trial evaluating a vitamin C, thiamine, cyanocobalamine, pyridoxine, and hydrocortisone regimen in sepsis and septic shock has compl…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Vitamin C, Thiamine, and Steroids in Sepsis [Phase 3]
Phase 3 trial update on vitamin C, thiamine, and steroids for sepsis has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-09-09Clinical Trial Update: The Role of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis (NEC) in Pre-term Infants [Phase 2]
A Phase 2 clinical trial evaluating whether Lactobacillus reuteri can prevent necrotizing enterocolitis in pre-term infants, with sepsis as …
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock [Phase 1, Phase 2]
A pharmacokinetic and biomarker study of pioglitazone conducted in adolescents with severe sepsis and septic shock completed Phase 1 and Pha…
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Levels of 'Hypophosphatemia Affect Outcome of Septic Patients in ICU [Phase 4]
A Phase 4 clinical trial evaluating whether hypophosphatemia affects outcomes in septic patients in the ICU is ongoing; current status is un…
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CLINICAL_TRIALS trial_result · 2020-07-30Clinical Trial Update: suPAR to Guide Antibiotics in Emergency Department [Phase 2, Phase 3]
Phase 2/3 trial investigating suPAR-guided antibiotics in emergency department for sepsis.
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CLINICAL_TRIALS trial_result · 2020-07-29Clinical Trial Update: A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis [Phase 2]
Phase 2 clinical trial update for validation and restoration of immune dysfunction in severe infections and sepsis has completed.
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CLINICAL_TRIALS trial_result · 2020-07-09Clinical Trial Update: A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients [Phase 2]
Phase 2 trial evaluating IL-7 to restore absolute lymphocyte counts in patients with severe sepsis and septic shock; study completed with re…
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CLINICAL_TRIALS trial_result · 2020-06-18Clinical Trial Update: Effect of Emergency Department Care Reorganization on Door-to-antibiotic Times for Sepsis (LDS SWARM)
A completed trial assessing how emergency department care reorganization affected door-to-antibiotic times in sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2020-04-27Clinical Trial Update: Prophylactic Probiotics to Extremely Low Birth Weight Prematures [Phase 2]
Phase 2 trial of prophylactic probiotics in extremely low birth weight preterm infants completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2020-04-22Clinical Trial Update: Impact of a Procalcitonin Testing and Treatment Algorithm on Antibiotic Use and Outcomes in the Pediatric Intensive Care Unit [NA]
Completed pediatric ICU trial evaluating procalcitonin-based testing and treatment algorithm to reduce antibiotic use and influence outcomes…
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CLINICAL_TRIALS trial_result · 2020-04-21Clinical Trial Update: Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy [Phase 3]
Phase 3 trial assessing ART-123 in adults with severe sepsis and coagulopathy has completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-13Clinical Trial Update: Efficacy and Pharmacokinetics of Meropenem in Severe Septic Patients [Phase 4]
Phase 4 trial update evaluating efficacy and pharmacokinetics of meropenem in severe septic patients.
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study) [Phase 2]
A Phase 2 clinical trial update investigating evolocumab for PCSK9 lowering in early acute sepsis (PLEASe Study).
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CLINICAL_TRIALS trial_result · 2020-03-02Clinical Trial Update: Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure [Phase 4]
Phase 4 trial update on sedative medications in patients with sepsis and respiratory failure, including agitation management; results posted…