Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the MODIFY Trial) [Phase 3]
Phase 3 MODIFY trial evaluating procalcitonin-guidance and molecular-guided diagnosis for therapy of severe infections; the study focusing o…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: PIVO Use for Blood Cultures in the Emergency Department
Status update for an Intermountain Health Care-sponsored trial evaluating the PIVO device for blood culture collection in the emergency depa…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation [Phase 2, Phase 3]
This clinical trial update indicates ongoing Phase 2/Phase 3 studies evaluating microbiota transplantation to treat acute lung injury caused…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Immunothrombosis With Septic Shock Undergoing Renal Replacement Therapy With the OXIRIS Membrane
A clinical trial evaluating the use of the OXIRIS CRRT membrane to address immunothrombosis in septic shock patients undergoing renal replac…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients
IMMUNOREA is a clinical trial studying immunological and inflammatory determinants of prognosis in intensive care patients; recruitment is o…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Defining Volume Status in Sepsis With Extracellular Water Measurement
A Uppsala University–sponsored clinical trial is recruiting to define volume status in sepsis using extracellular water measurement.
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Predictive Value of the Uric Acid/Albumin Ratio and Lactate in Sepsis Patients
A clinical study from Istinye University is investigating whether the uric acid/albumin ratio and lactate can predict sepsis-related mortali…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Association Between Early FiO₂ Exposure and Changes in the Uric Acid/Albumin Ratio in Septic ICU Patients
Clinical trial update from Istinye University examining whether early exposure to high FiO2 influences the uric acid/albumin ratio in septic…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: İntensive Care Sepsis Prevelance in Turkey (INSEP-TURK)
This clinical trial update notes an active-not-recruiting study in Turkey (INSEP-TURK) assessing the prevalence of sepsis and septic shock i…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS) [Phase 1]
A Phase 1 safety study evaluating inhaled carbon monoxide as a treatment for pneumonia and sepsis-induced acute respiratory distress syndrom…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention [Phase 1]
Phase 1 clinical trial at Children's Hospital of Philadelphia is evaluating vancomycin and acute kidney injury in sepsis patients and is cur…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: STeroids and Enhanced Spectrum Antibiotics for the Treatment of Patients in Africa With Refractory Sepsis [Phase 3]
Phase 3 clinical trial update evaluating steroids and broad-spectrum antibiotics for the treatment of refractory sepsis in Africa. Tuberculo…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Inflammatory Mediators of Acute Kidney Injury in Intensive Care
A ClinicalTrials.gov update describing an ongoing study on inflammatory mediators of acute kidney injury in ICU patients, including those wi…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Mechanisms of Precise Immune Cell Phenotyping and Prognostic Prediction in Severe Infection
This ClinicalTrials.gov entry describes an upcoming study investigating precise immune cell phenotyping and prognostic prediction in sepsis,…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided and Absolute Procalcitonin Value-guided Antibiotic Initiation in Reducing Unnecessary Antibiotic Use in Critically Ill Patients [NA]
This clinical trial compares procalcitonin kinetics-guided antibiotic initiation versus absolute procalcitonin value-guided initiation to re…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Comparison of Sepsis Prediction Algorithms
Emory University is conducting a study comparing sepsis prediction algorithms, but the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
Study evaluating neutrophil phenotypic profiling and organ injury assessment in patients with sepsis. It is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: TRIM25 in Septic Patients
A clinical trial update indicates a study evaluating TRIM25 in septic patients is currently enrolling by invitation at Ruijin Hospital.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: The Extended Study of Prevalence of Infection in Intensive Care IV
Update on the extended study assessing prevalence of infection in intensive care patients; the trial is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey
A clinical trial protocol to validate the SOFA-2 scoring system for predicting mortality and Sepsis-3 prevalence in Turkish patients with se…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis
A recruiting clinical trial investigating dysfunctional myelopoiesis and myeloid-derived suppressor cells in sepsis, with trauma injury as a…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Pathological Myeloid Activation After Sepsis and Trauma
A clinical trial sponsored by the University of Florida is investigating pathological myeloid activation after sepsis and trauma. The study …
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Fluid Management and Individualized Resuscitation in Sepsis [NA]
The listing shows a recruiting clinical trial evaluating fluid management and individualized resuscitation in sepsis.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Accelerating Recovery After ICU Admission: Post-discharge Supplementation With Pasteurized Akkermansia Muciniphila. [NA]
A clinical trial is evaluating post-discharge supplementation with pasteurized Akkermansia muciniphila for ICU survivors, including patients…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 randomized study evaluating point-of-care AI assistance to improve outcomes in critic…