Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Remote Ischemic Preconditioning in Septic Patients [NA]
A clinical trial is recruiting to evaluate remote ischemic preconditioning in septic patients with acute kidney injury.
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Mechanisms of Acute Kidney Injury in Severe Infections
A recruiting clinical study at Uppsala University Hospital investigating the mechanisms of acute kidney injury in severe infections (sepsis)…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: The Impact of Selective Vitamin D Receptor Activation on Clinical Outcomes in Septic Patients [NA]
This clinical trial investigates selective activation of the vitamin D receptor to improve outcomes in septic patients; the study status is …
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Hemodynamic Phenotype-Based,Capillary Refill Time-Targeted Resuscitation In Early Septic Shock:ANDROMEDA-SHOCK-2 [NA]
The ANDROMEDA-SHOCK-2 trial evaluating hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock is cu…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock [Phase 2]
Phase 2 clinical trial evaluating umbilical cord-derived mesenchymal stromal cells as cellular immunotherapy for septic shock, currently rec…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Early Administration of Norepinephrine in Sepsis [Phase 4]
A Phase 4 clinical trial is evaluating early administration of norepinephrine in sepsis and is currently recruiting. The study investigates …
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Early Detection of At-risk Septic Patients
A clinical trial led by University Hospital Southampton NHS Foundation Trust is actively recruiting to test methods for early detection of a…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating CfDNA/NETs in Subjects with Sepsis [NA]
Status update on a clinical trial evaluating the NucleoCapture Device for reducing circulating cfDNA/NETs in sepsis patients; the study is n…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Overview of Botriomycoma in Children with a Central Line: Epidemiology, Risk Factors, Treatments
This clinical trial update reviews the epidemiology, risk factors, and treatment considerations for botriomycoma in children with central ve…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Validation of Hematological Indices [NA]
Clinical trial update for validation of hematological indices (NCT06476171) indicates the study is currently recruiting. The trial targets m…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS) [NA]
A recruiting clinical trial evaluating hemoperfusion with Polymyxin B for septic shock associated with severe endotoxemia in cardiac surgery…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock [Phase 3]
Phase 3 clinical trial update on using venous excess ultrasound to personalize resuscitation in septic shock; the study is currently not yet…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Detection of Sepsis Occurrence by Using Blood Fluorescence
An ongoing clinical trial is evaluating detection of sepsis occurrence using a blood fluorescence method. The study is sponsored by Ningbo M…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Predicts Mortality by AST/ALT Ration in Patients with Sepsis and Septic Shock During ICU Admissin
A NOT_YET_RECRUITING clinical trial evaluating whether the AST/ALT ratio can predict mortality in patients with sepsis and septic shock in t…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Cytokine REmoval in CRitically Ill PAtients Requiring Surgical Therapy for Infective Endocarditis (RECReATE) [NA]
This ClinicalTrials.gov entry reports the RECReATE study evaluating cytokine removal in critically ill patients undergoing surgery for infec…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Fibrinolysis Resistance in Infection and Trauma
A clinical trial investigating fibrinolysis resistance in sepsis, septic shock, and trauma is currently recruiting. Sponsor is Anders Aneman…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Real-World Pharmacokinetic/Pharmacodynamic Study of Eravacycline in Critically III Patients
A real-world PK/PD study examining eravacycline exposure and activity in critically ill patients with infections to inform dosing in severe …
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: A Multicenter Prospective Observational Study to Derive and Verify the Performance of a Host-response Based Diagnostic Tool for Early Detection of Severe Infections.
This is a multicenter prospective observational study evaluating the performance of a host-response diagnostic tool for early detection of s…
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Study and Role of Inflammasome in Platelet Activation During Bacterial And/or Viral Sepsis
A clinical trial evaluating the role of the inflammasome in platelet activation during sepsis (bacterial or viral), currently recruiting in …
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Impact of the Introduction of a Performance Improvement Program on the Initial Management of Sepsis and Septic Shock in Adults in the Emergency Department: a Before-and-after Study (IPA-SOS)
This clinical trial evaluates how a Performance Improvement Program affects initial management of sepsis and septic shock in adult emergency…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Correlation Between PLA Levels and Disease Severity in Patients With Sepsis Cardiac Insufficiency
A clinical trial is recruiting to evaluate the relationship between PLA levels and disease severity in patients with sepsis and cardiac insu…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: ICITRU : Randomized Trial of Immunonutrition With L-citrulline in Patients Hospitalized in Intensive Care for Sepsis or Septic Shock [NA]
A randomized trial evaluating immunonutrition with L-citrulline in ICU patients with sepsis or septic shock is currently recruiting.
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis [Phase 1, Phase 2]
This clinical trial update outlines planned Phase 1 and Phase 2 studies evaluating novel and established therapies in a human intravenous LP…
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: Rapid Molecular Diagnosis of Sepsis in the Intensive Care Unit
This clinical trial update describes a study evaluating rapid molecular diagnostic methods for identifying sepsis pathogens in ICU patients,…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Fosfomycin I.v. for Treatment of Severely Infected Patients
An intravenous fosfomycin trial is recruiting to evaluate its use in severely infected patients across multiple bacterial infection indicati…