Schistosomiasis
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CLINICAL_TRIALS trial_result · 2019-12-09Clinical Trial Update: Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children [Phase 2]
Phase 2b-Sn trial update for an anti-schistosomiasis Sm14 vaccine in school children completed.
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CLINICAL_TRIALS trial_result · 2019-11-20Clinical Trial Update: An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni) [Phase 2]
Phase 2 open-label trial assessing safety and efficacy of a dose-finding regimen in children and infants with schistosomiasis (Schistosoma m…
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CLINICAL_TRIALS research · 2019-01-18Clinical Trial Update: Praziquantel-Pharmacokinetic Study [Phase 1]
Phase 1 pharmacokinetic study of praziquantel conducted to characterize absorption and metabolism in the context of Schistosomiasis.
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FDA approval · 2019-01-08FDA Approved: BILTRICIDE — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approved a supplemental application for Biltricide (praziquantel) from Bayer HealthCare Pharmaceuticals Inc. This approval results in an…
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CLINICAL_TRIALS research · 2018-03-08Clinical Trial Update: Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa
A completed clinical trial update examining the prevalence of chronic kidney disease in Sub-Saharan Africa and its risk factors. The study a…
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions [Phase 2]
Phase 2 trial update on the Sm14 vaccine assessing safety and immune response in adults from endemic regions for schistosomiasis; study comp…
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FDA approval · 2017-11-27FDA Approved: PRAZIQUANTEL — Original Application (Endo USA, Inc.)
The FDA approved Endo USA, Inc.'s original application for praziquantel, enabling a generic version of the antihelminthic.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Health Benefits of Repeated Treatment in Pediatric Schistosomiasis
A completed clinical trial investigated the health benefits of repeated treatment for pediatric schistosomiasis.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Schistosoma Mansoni in Mwanza Region, Tanzania [NA]
A completed clinical trial in the Mwanza Region of Tanzania evaluating Schistosoma mansoni infection, sponsored by DBL - Institute for Healt…
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders
This completed clinical trial update reports on diagnosing a range of neglected tropical diseases in patients with persistent digestive diso…
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis [Phase 1]
Phase 1 clinical trial evaluating the safety of the sm14 vaccine against schistosomiasis has completed.
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CLINICAL_TRIALS trial_result · 2015-02-20Clinical Trial Update: Safety and Efficacy of Mirazid for Schistosomiasis Treatment [Phase 3]
Phase 3 trial evaluating Mirazid for schistosomiasis has completed, reporting safety and efficacy data.
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FDA approval · 2014-11-20FDA Approved: BILTRICIDE — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approved a supplemental application for Biltricide (praziquantel) from Bayer HealthCare Pharmaceuticals Inc., authorizing changes to the…
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CLINICAL_TRIALS trial_result · 2014-09-23Clinical Trial Update: Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania [NA]
A completed clinical trial in Tanzania assessed schistosome and intestinal worm infections and their impact on malaria morbidity among schoo…
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CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: Arachidonic Acid Treatment Against Schistosomiasis Infection in Children [NA]
A clinical trial evaluating arachidonic acid as a treatment for schistosomiasis in children has completed.
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FDA approval · 2014-02-25FDA Approved: BILTRICIDE — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approved a supplemental application for Biltricide (praziquantel) from Bayer HealthCare Pharmaceuticals, authorizing changes to the prod…
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: S. Japonicum and Pregnancy Outcomes [Phase 2]
Phase 2 clinical trial evaluating Schistosoma japonicum infection and pregnancy outcomes has completed and results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma [NA]
A completed clinical trial assessed how malaria, hookworm infection, and schistosomiasis affect iron absorption and utilization in adolescen…
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CLINICAL_TRIALS trial_result · 2013-08-27Clinical Trial Update: Clinical Trial of Bilhvax,a Vaccine Candidate Against Schistosomiasis [Phase 1]
This report summarizes the completion of a Phase 1 clinical trial evaluating Bilhvax, a vaccine candidate for schistosomiasis.
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CLINICAL_TRIALS research · 2013-06-05Clinical Trial Update: Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis [NA]
A clinical trial update evaluating strategies to improve uptake of preventive treatment for intestinal schistosomiasis.
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CLINICAL_TRIALS trial_result · 2013-01-17Clinical Trial Update: Schistosoma Haematobium Infections and Praziquantel [Phase 3]
Phase 3 clinical trial update for praziquantel in treating Schistosomiasis caused by Schistosoma haematobium; the study is reported as compl…
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CLINICAL_TRIALS trial_result · 2012-03-14Clinical Trial Update: Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal
A completed clinical trial in northern Senegal evaluated how schistosomiasis influences vaccine responses, anemia, and nutritional outcomes …
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CLINICAL_TRIALS research · 2011-10-25Clinical Trial Update: Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana [Phase 4]
A Phase 4 clinical trial update on ACT-IPT in schoolchildren in Kassena-Nankana, Ghana. The study assesses intermittent preventive treatment…
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CLINICAL_TRIALS trial_result · 2011-03-04Clinical Trial Update: Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires
This clinical trial update reports on a completed study examining whether serum antibody profiles against Plasmodium falciparum antigens cor…
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CLINICAL_TRIALS research · 2010-12-15Clinical Trial Update: Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis [NA]
This clinical trial update from Addis Ababa University describes investigating antioxidant supplements to reverse schistosomal peri-portal f…