Sarcoma
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer [Phase 2]
This document provides an update on the Phase 2 SMMART-ACT precision medicine trial. It targets patients with advanced breast, ovarian, panc…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene. [Phase 2]
A Phase 2 clinical trial is evaluating zanidatamab for solid tumors with HER2 gene alterations across multiple indications and is currently …
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: A Study of CRD3874-SI in People With Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for CRD3874-SI in people with solid tumors. The study is currently recruiting and targets sarcoma an…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: A Study of Pembrolizumab in People With Ultra-Rare Sarcomas [Phase 2]
A Phase 2 clinical trial update for pembrolizumab in ultra-rare sarcomas, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: WeCanManage. An mHealth Self-management Tool [NA]
The document notes the completion of a clinical trial evaluating WeCanManage, an mHealth self-management tool, for patients with breast canc…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Intravital Microscopy in Human Solid Tumors [NA]
Mayo Clinic is conducting a clinical trial using intravital microscopy in multiple solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II Trial [Phase 2]
Phase II multicenter trial evaluating pembrolizumab (MK3475) in combination with metronomic cyclophosphamide for advanced sarcoma; results h…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Quality of Life and Medical Care of Long-term Sarcoma Survivors in Germany (PROSa+)
PROSa+ is a German clinical study assessing quality of life and medical care needs among long-term sarcoma survivors. The study is currently…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot Study [NA]
A pilot PET imaging trial using the 124I-labeled humanized antibody 3F8 to visualize solid tumors, including melanoma, neuroblastoma, and sa…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Preventive Application of Single-use Negative Pressure Wound Therapy (sNPWT) in the Postoperative Course of Radiotreatated Limb Sarcoma Surgery [NA]
This clinical trial update indicates that a study is currently recruiting to evaluate the preventive use of single-use negative pressure wou…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas [Phase 1]
Phase 1 clinical trial evaluating the combination of BOLD-100 with doxorubicin in advanced soft tissue sarcoma; study status is not yet recr…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group
Update on enrollment for the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group; the network remains active but is no…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for HiFiBiO's HFB200301 as a single agent and in combination with tislelizumab in adults with advanc…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
This is a screening study by TScan Therapeutics to collect samples for tumor-associated antigens, HLA typing, and HLA loss of heterozygosity…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: PROMIS and Mobility Evaluation in Sarcoma Patients
A clinical trial is evaluating PROMIS and mobility in sarcoma patients and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Pediatric Radiation Therapy Registry
A pediatric radiation therapy registry at Johns Hopkins is currently recruiting to collect data on treatment for sarcoma and pediatric brain…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Genomic Structural Variation in Cancer Susceptibility
This clinical trial update discusses ongoing research on genomic structural variation in cancer susceptibility and lists several cancer cond…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma [Phase 2]
Phase 2 study of talimogene laherparepvec (T-VEC) in combination with pembrolizumab in metastatic and/or locally advanced sarcoma reports re…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: A Study Involving Collection of Samples and Data From Sarcoma Patients Receiving Immunotherapy
A Memorial Sloan Kettering Cancer Center study is collecting samples and data from sarcoma patients receiving immunotherapy; enrollment is b…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring) [NA]
A Mayo Clinic-sponsored WATCH trial evaluating a wearable AI system for cardiac function monitoring is currently recruiting in patients with…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: YASU Research Registry: For Young Adults With Cancer
Clinical trial update indicating termination of the YASU Research Registry for young adults with cancer, listing several cancer conditions i…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Cardiotoxic Effects of Chemotherapy in Patients With Sarcomas: A Two and Three-dimensional Echocardiographic Speckle Tracking Imaging Study
A Mayo Clinic-led trial evaluating cardiotoxic effects of chemotherapy in patients with sarcoma using two- and three-dimensional echocardiog…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Machine Learning Applied to EHRs Data of Patients With Sarcoma
Completed study from the University of Milano Bicocca applying machine learning to electronic health records of patients with sarcoma (inclu…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of intratumoral MVR-T3011 given alone or with pembrolizumab in adults with advanced o…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT [NA]
This entry reports a clinical trial update on caloric restriction in patients with sarcoma undergoing pre-operative radiotherapy. The study …