Rheumatic Heart Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial [Phase 2]
Phase 2 clinical trial comparing intramuscular penicillin G benzathine versus oral penicillin V prophylaxis to prevent progression of latent…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop [Phase 3]
GOAL-Stop is a Phase 3 non-inferiority trial to determine if stopping penicillin prophylaxis in early rheumatic heart disease is not inferio…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)
This clinical trial update describes a long-term follow-up study (GOAL-Post) of participants from the GOAL trial and provides extended outco…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: RhEumatiC Heart diseAse Genetics
Clinical trial update on genetics research related to rheumatic heart disease; the trial status is completed.
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: Comparison of Wire Assisted Percutaneous Balloon Mitral Valvulotomy With Standard Inoue Balloon Valvulotomy [NA]
A completed clinical trial compared wire-assisted percutaneous balloon mitral valvulotomy versus the standard Inoue balloon technique for rh…
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CLINICAL_TRIALS trial_result · 2022-11-21Clinical Trial Update: Dapagliflozin Effect on Rheumatic Mitral Stenosis [Phase 3]
Phase 3 trial evaluating dapagliflozin for rheumatic mitral stenosis in patients with rheumatic heart disease and heart failure.
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CLINICAL_TRIALS trial_result · 2022-10-05Clinical Trial Update: INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority [Phase 3]
A Phase 3 completed trial comparing vitamin K antagonists, rivaroxaban, and aspirin for rheumatic heart disease in rheumatic heart disease p…
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: RIvoraxaban in Mitral Stenosis [Phase 3]
Phase 3 trial update for rivaroxaban in mitral stenosis has been terminated.
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients [Phase 3]
Phase 3 trial investigating ramipril's effect on suppressing ST2 expression in patients with rheumatic mitral stenosis.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Determining the Impact of Penicillin in Latent RHD: The GOAL Trial [Phase 2]
A Phase 2 clinical trial update investigating the impact of penicillin in latent rheumatic heart disease in children; current status is unkn…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Prevalence of Rheumatic Heart Disease Among Pregnant Women in Kenya
A completed clinical trial update assessing the prevalence of rheumatic heart disease among pregnant women in Kenya, sponsored by Moi Univer…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Rheumatic Heart Disease Study in Lusaka
A University of Zambia–led clinical trial evaluating a rheumatic heart disease intervention in Lusaka has completed.
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CLINICAL_TRIALS trial_result · 2016-08-29Clinical Trial Update: Mobile Health in Structural Heart Disease [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial update on a mobile health intervention for structural heart disease.
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Rheumatic Heart Disease in Peru: Prevalence and Cardiovascular Outcomes Among Schoolchildren
A completed clinical trial assessing the prevalence of rheumatic heart disease and cardiovascular outcomes among Peruvian schoolchildren.
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: Ring Versus Suture Annuloplasty For Functional Tricuspid Regurgitation In Rheumatic Mitral Valve Diseases [NA]
A clinical trial comparing ring versus suture annuloplasty for functional tricuspid regurgitation in patients with rheumatic mitral valve di…
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CLINICAL_TRIALS trial_result · 2014-07-15Clinical Trial Update: Genetic Susceptibility to Rheumatic Heart Disease in the Pacific Region
A completed clinical trial from the University of Oxford investigates genetic susceptibility to rheumatic heart disease in the Pacific regio…
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CLINICAL_TRIALS trial_result · 2014-05-28Clinical Trial Update: Validity Study of Glutamine to Improve Cardiac Function in Cardiac Surgery [Phase 2]
The document reports the completion of a Phase 2 validity study evaluating glutamine to improve cardiac function in patients undergoing card…
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CLINICAL_TRIALS trial_result · 2012-10-11Clinical Trial Update: N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve Replacement [Phase 2]
A Phase 2 clinical trial evaluating N-acetylcysteine for renal protection in patients with rheumatic heart disease undergoing valve replacem…
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CLINICAL_TRIALS trial_result · 2012-07-26Clinical Trial Update: Effect of Simvastatin on Cardiac Function [NA]
Completed clinical trial evaluating the effect of simvastatin on cardiac function in patients with rheumatic heart disease and congenital he…
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CLINICAL_TRIALS trial_result · 2008-06-05Clinical Trial Update: Dental Anesthesia in Pregnant Women With Rheumatic Heart Disease [Phase 1]
The update reports the completion of a Phase 1 study evaluating dental anesthesia in pregnant women with rheumatic heart disease. No detaile…