Rett Syndrome
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Pilot Study of the Effects of the Desipramine on the Neurovegetative Parameters of the Child With Rett Syndrome [Phase 2]
This document reports the completion of a Phase 2 pilot clinical trial evaluating the effects of desipramine on neurovegetative parameters i…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Phase 2 Study of EPI-743 for Treatment of Rett Syndrome [Phase 2]
Phase 2 study of EPI-743 for Rett syndrome has completed, with the trial status listed as COMPLETED on ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Study to Assess Safety and Efficacy of Fingolimod in Children With Rett Syndrome [Phase 1, Phase 2]
This completed Phase 1/2 trial evaluated the safety and potential efficacy of fingolimod for Rett syndrome in pediatric patients.
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CLINICAL_TRIALS trial_result · 2018-03-26Clinical Trial Update: Treatment of Rett Syndrome With Recombinant Human IGF-1 [Phase 2]
A Phase 2 trial of recombinant human insulin-like growth factor-1 (IGF-1) for Rett syndrome has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: A Safety Study of NNZ-2566 in Patients With Rett Syndrome [Phase 2]
Phase 2 safety study of NNZ-2566 in Rett syndrome has completed.
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: An Exploratory Trial of Ketamine for the Treatment of Rett Syndrome [Phase 1]
An exploratory Phase 1 trial evaluating ketamine for Rett Syndrome was terminated.
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CLINICAL_TRIALS trial_result · 2017-06-22Clinical Trial Update: Treatment of Rett Syndrome With rhIGF-1 (Mecasermin [rDNA]Injection) [Phase 1]
This entry reports results from a Phase 1 trial evaluating rhIGF-1 (mecasermin [rDNA] Injection) for Rett syndrome. The study has completed,…
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Genetic and Physical Characteristics of Rett Syndrome
A completed clinical trial update examining the genetic and physical characteristics of Rett syndrome, including MECP2 duplication syndrome.
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization [NA]
A completed clinical trial reports identification of new genes involved in the molecular etiology of Rett syndrome using DNA microarray comp…
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PW
This clinical trial update reports the completion of a study examining sleep abnormalities in individuals with Rett syndrome, Angelman syndr…
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Trial of Dextromethorphan in Rett Syndrome [Phase 2]
Phase 2 trial of dextromethorphan in Rett syndrome was terminated; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2011-02-17Clinical Trial Update: Creatine Metabolism in Rett Syndrome
Completed clinical trial evaluating creatine metabolism in individuals with Rett syndrome conducted by Maastricht University Medical Center.
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD) [Phase 3]
Phase 3 randomized trial comparing risperidone to placebo in children with autism spectrum disorder and related pervasive developmental diso…
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: Effects of Creatine Supplementation in Rett Syndrome [NA]
This clinical trial evaluated the effects of creatine supplementation in individuals with Rett syndrome and has completed.
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CLINICAL_TRIALS trial_result · 2010-03-04Clinical Trial Update: Metabolic Evaluation of Nutrition in Rett Syndrome
This completed clinical trial evaluated metabolic aspects of nutrition in Rett syndrome.
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CLINICAL_TRIALS trial_result · 2008-03-07Clinical Trial Update: Functional Abilities in Rett Syndrome
This is an update on a completed clinical trial evaluating functional abilities in individuals with Rett syndrome.