Retinoblastoma
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
A National Cancer Institute–sponsored clinical trial is conducting comprehensive omics analyses of pediatric and adult solid tumors and esta…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Familial Investigations of Childhood Cancer Predisposition
An ongoing St. Jude-led clinical trial is investigating familial cancer predisposition syndromes in children and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Retinoblastoma Patient Clinical Database and Tissue Repository
Recruitment is ongoing for a Retinoblastoma patient clinical database and tissue repository.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Retinoblastoma Consolidation in Egyptians
This entry notes a clinical trial in Egypt (Assiut University) evaluating consolidation therapy for retinoblastoma, with the study status no…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Retinoblastoma Phase II Expanded Access Clinical Trial [Phase 2]
Phase II expanded-access clinical trial for retinoblastoma sponsored by Targeted Therapy Technologies, LLC is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Detailed Phenotypic and Genotype Study to Correlate RB1 Mutations Relating to Primary Ocular Tumors and Secondary Extra-ocular Metastasis.
A University of Washington study investigates RB1 gene mutations to correlate phenotypic features of retinoblastoma with potential extra-ocu…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma
A clinical trial update indicating ongoing recruitment for a study sponsored by the French Africa Pediatric Oncology Group, evaluating thera…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Study to Give Treatment Inside the Eye to Treat Retinoblastoma [Phase 2]
A Phase 2 clinical trial sponsored by Children's Oncology Group is evaluating an intravitreal treatment for retinoblastoma and is currently …
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Retinoblastoma Survivor Study: Assessment of General Health and Quality of Life
This clinical trial update describes an observational study assessing general health and quality of life in retinoblastoma survivors.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009) [Phase 2]
Phase 2 trial update on adjuvant treatment after primary enucleation for extensive unilateral retinoblastoma (RB SFCE 2009).
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Can Pretreatment MRI be Used to Predict Intra-arterial Chemotherapy Response in Retinoblastoma?
A prospective study is assessing whether pretreatment MRI can predict how retinoblastoma will respond to intra-arterial chemotherapy; the tr…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma [Phase 1]
Phase 1 clinical trial update on GPC2 CAR T cells for relapsed/refractory neuroblastoma and metastatic retinoblastoma; currently recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors
An ongoing study at Amsterdam University Medical Center is evaluating cognitive functioning and health-related quality of life in retinoblas…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome [Phase 2, Phase 3]
An ongoing Phase 2/Phase 3 clinical trial from Institut Curie is evaluating ocular conservative treatment strategies for retinoblastoma, foc…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Conservative Treatments of Retinoblastoma [Phase 2]
This update reports a Phase 2 clinical trial on conservative treatments for retinoblastoma in children, currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Studying Health Outcomes After Treatment in Patients With Retinoblastoma
A clinical trial investigating health outcomes after treatment in retinoblastoma patients is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: MRI Screening of Second Primary Cancer Occurring Within Radiation Fields After Treatment by External Beam Radiation Therapy for Hereditary Retinoblastoma (DepiSCARRH) [NA]
This clinical trial update describes MRI screening for a second primary cancer within radiation fields after external beam radiation therapy…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Effect of Treatment Modality on Psychosocial Functioning of Survivors of Unilateral Retinoblastoma
A clinical trial is examining how different treatment modalities impact psychosocial functioning in survivors of unilateral retinoblastoma; …
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
This clinical trial sponsored by Memorial Sloan Kettering Cancer Center investigates whether multiple anesthesia exposures affect cognitive …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Targeting NUDT21 siRNA Drugs for Patients With Refractory Retinoblastoma [EARLY_Phase 1]
An early Phase 1 clinical trial is evaluating NUDT21-targeting siRNA therapies for patients with refractory retinoblastoma. The study is spo…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: High-dose Topotecan for Retinoblastoma With Recurrent or Refractory Vitreous Seed [EARLY_Phase 1]
A Phase 1 early trial evaluating high-dose topotecan for retinoblastoma with recurrent or refractory vitreous seeds is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Intrathecal Chemotherapy for Central Nervous System Metastasis in Retinoblastoma [NA]
An update on an ongoing clinical trial evaluating intrathecal chemotherapy for central nervous system metastasis in retinoblastoma. The tria…