Retinitis Pigmentosa
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
This update describes a clinical trial evaluating the rate of progression of PCDH15-related retinal degeneration in Usher syndrome type 1F; …
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: BS01 in Patients With Retinitis Pigmentosa [Phase 1, Phase 2]
BS01 is being studied in a Phase 1/2 clinical trial for Retinitis Pigmentosa and is currently recruiting. The sponsor and developer is Bioni…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment [NA]
This clinical trial update from the University of Waterloo describes a brain stimulation study to assess orientation and mobility in adults …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa [Phase 1, Phase 2]
This document reports a first-in-human, Phase 1/2 study of CPK850 for RLBP1-related Retinitis Pigmentosa, sponsored by Novartis, which is cu…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Non-invasive Ultrasound Retinal Stimulation for Vision Restoration [NA]
A USC-led clinical trial is evaluating non-invasive ultrasound retinal stimulation as a potential vision-restoration therapy for Age-Related…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: UGX202 Injection in Patients With Advanced Retinitis Pigmentosa [EARLY_Phase 1]
This entry reports an early-phase 1 clinical trial of UGX202 in patients with advanced Retinitis Pigmentosa, with status not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Wide Field OCTA in Ocular Diseases
Clinical trial update on a wide-field optical coherence tomography angiography (OCTA) study across several ocular diseases, sponsored by IRC…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Safety and Efficacy of NPI-001 Tablets for RP Associated With Usher Syndrome [Phase 1, Phase 2]
This document provides an update on a Phase 1/2 clinical trial of NPI-001 tablets for retinitis pigmentosa associated with Usher syndrome, c…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome [Phase 3]
Phase 3 clinical trial update for NPI-001 aimed at preserving photoreceptors in retinitis pigmentosa associated with Usher syndrome; the stu…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Repository for Inherited Eye Diseases
Completed update on the Repository for Inherited Eye Diseases by the National Eye Institute, describing resources related to Retinitis Pigme…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Inherited Retinal Diseases: Natural History and Genotype-Phenotype Correlations
This clinical trial update describes inherited retinal diseases, focusing on natural history and genotype-phenotype correlations, with the s…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001 [Phase 1, Phase 2]
A two-arm, repeat-dose, open-label Phase 1/2 trial evaluating two intravitreal doses of VP-001 in participants with PRPF31 mutation-associat…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) [Phase 1, Phase 2]
An early-phase (Phase 1/2) dose-escalation study is investigating intravitreal KIO-301 for Retinitis pigmentosa and choroideremia; the trial…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: High Resolution, High-speed Multimodal Ophthalmic Imaging [NA]
This clinical trial update describes recruitment for a study of high-resolution, high-speed multimodal ophthalmic imaging technologies evalu…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa [Phase 2]
Kiora Pharmaceuticals is conducting a Phase II intravitreal study of KIO-301 in late-stage retinitis pigmentosa and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Natural History Study of Patients With EYS-Associated RP
This entry reports a natural history study of patients with EYS-associated retinitis pigmentosa. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: FIGHT-RP 1 Extension Study [Phase 1]
The FIGHT-RP 1 extension study for retinitis pigmentosa is a Phase 1 trial sponsored by Johns Hopkins University and is currently active but…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Retinitis Pigmentosa Clinical Measures and Repeatability Testing of Potential Outcome Measures
A completed clinical trial update assessing the repeatability and usefulness of potential outcome measures for Retinitis Pigmentosa.
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration [Phase 1]
Phase 1 trial investigating the effects of disulfiram (Antabuse) on visual acuity in patients with retinal degeneration; the study is curren…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Pilot Study of AuTNA I [NA]
Pilot study of AuTNA I for retinitis pigmentosa is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Promising ROd-cone DYstrophy Gene therapY [Phase 1, Phase 2]
SparingVision reports a Phase 1/2 clinical trial evaluating a rod-cone dystrophy gene therapy for retinitis pigmentosa, with recruitment ong…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: CNS10-NPC for the Treatment of RP [Phase 1]
A Phase 1 study evaluating CNS10-NPC for the treatment of retinitis pigmentosa, with the trial status listed as active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis [Phase 1, Phase 2]
Ocugen's OCU400 is being studied in a Phase 1/2 trial to assess safety and efficacy in patients with Retinitis pigmentosa and Leber congenit…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Study of BEST1 Vitelliform Macular Dystrophy
Clinical trial update announcing recruitment for BEST1-related vitelliform macular dystrophy study sponsored by Columbia University.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: A Multicenter, Randomized, Double-Blind, Controlled Clinical Study of Minocycline for the Treatment of Retinitis Pigmentosa [Phase 3]
A multicenter Phase 3 randomized trial evaluating minocycline for Retinitis pigmentosa. The study is currently not yet recruiting.