Respiratory Distress Syndrome of the Newborn
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa [Phase 4]
A Phase 4 pragmatic clinical trial in Africa is evaluating treatment strategies for neonatal respiratory distress syndrome due to surfactant…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Premedication for Less Invasive Surfactant Administration Study (PRELISA) [Phase 4]
The PRELISA trial evaluating premedication for less invasive surfactant administration in newborns with respiratory distress syndrome has co…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Pulmonary Function Using Non-invasive Forced Oscillometry [NA]
Clinical trial update reporting pulmonary function assessment in premature and newborn infants using non-invasive forced oscillometry; resul…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Automated Versus Manual Oxygen Control in Preterm Babies on Respiratory Support [NA]
Completed clinical trial comparing automated versus manual oxygen control in preterm infants on respiratory support.
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Diaphragmatic Ultrasound and Thoracic Fluid Content for Prediction of Non-Invasive Ventilation Failure in Neonates
Completed trial evaluating diaphragmatic ultrasound and thoracic fluid content as predictors of non-invasive ventilation failure in neonates…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Heterogeneity Index in Neonatologist-performed Lung Ultrasound in Neonates Receiving Respiratory Support - a Pilot Study
An update on a pilot study evaluating the heterogeneity index in neonatologist-performed lung ultrasound in newborns receiving respiratory s…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Tracheal Ultrasound for Confirmation of ETT Placement in NICU [NA]
A completed clinical trial from Ain Shams University evaluating tracheal ultrasound to confirm endotracheal tube placement in preterm neonat…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: An Educational Intervention to Improve the Success of Intubation in Newborns Using a Video Laryngoscope by Reducing the Time the Procedure Takes. [NA]
A clinical trial in University College Dublin is evaluating an educational intervention to improve success of endotracheal intubation in new…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Evaluation of the Impact of SpO2 Averaging Time on Performance of an Automatic FiO2 Control System: a Randomized Study [NA]
A randomized study evaluating how SpO2 averaging time affects the performance of an automated FiO2 control system in newborns with respirato…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: A Stepped Wedge Cluster Randomised Trial of Video Versus Direct Laryngoscopy for Intubation of Newborn Infants [NA]
A stepped wedge cluster randomized trial is evaluating video laryngoscopy versus direct laryngoscopy for intubation of newborn infants; recr…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Surfactant Replacement Guided by Early Lung Ultrasound Score in Preterm Newborns With Respiratory Distress Syndrome
Clinical trial update reporting a completed study on surfactant replacement guided by early lung ultrasound scores in preterm newborns with …
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Flow-synchronized Nasal IMV in Preterm Infants [NA]
Clinical trial update noting the completion of a study evaluating flow-synchronized nasal intermittent mechanical ventilation in preterm inf…
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CLINICAL_TRIALS trial_result · 2022-08-24Clinical Trial Update: Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia [Phase 4]
Phase 4 clinical trial examining exogenous surfactant to prevent bronchopulmonary dysplasia in very preterm neonates has completed.
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CLINICAL_TRIALS trial_result · 2019-10-15Clinical Trial Update: LISA vs INSURE in the Treatment of Respiratory Distress Syndrome in Preterm Infants [Phase 2]
Phase 2 trial update comparing LISA versus INSURE for treatment of respiratory distress syndrome in preterm infants.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Streptococcal Infection and Respiratory Distress in Newborns
This is a completed clinical trial update from NICHD examining Group B streptococcal infection and respiratory distress syndrome of the newb…
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FDA label_change · 2015-05-04FDA Approved: CUROSURF — Supplemental Application (Chiesi USA, Inc.)
FDA approved a supplemental labeling application for Curosurf (poractant alfa) from Chiesi USA, Inc., resulting in updated product labeling.
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CLINICAL_TRIALS research · 2014-01-31Clinical Trial Update: Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonates [Phase 1]
Phase 1 clinical trial evaluating autologous cord blood infusion to prevent and treat complications in preterm neonates, sponsored by Pomera…
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CLINICAL_TRIALS trial_result · 2013-11-20Clinical Trial Update: Ventilatory Parameters and Inflammatory Responses of Neonates Ventilated by Different Modes of Ventilation [NA]
A completed study from Gazi University comparing ventilatory parameters and inflammatory responses in newborns with respiratory distress ven…
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CLINICAL_TRIALS trial_result · 2012-10-24Clinical Trial Update: Trial of Weaning of Nasal Continuous Positive Airway Pressure (CPAP) [NA]
A completed clinical trial evaluating weaning from nasal CPAP in preterm neonates with respiratory distress syndrome.
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CLINICAL_TRIALS trial_result · 2011-09-21Clinical Trial Update: Neural Control of Non-invasive Ventilation in the Preterm [Phase 1]
Phase 1 trial evaluating neural control of non-invasive ventilation in preterm infants with respiratory distress syndrome. The study status …
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Intratracheal Vitamin A Administration With Surfactant for Newborn Respiratory Distress Syndrome [Phase 3]
Phase 3 trial update evaluating intratracheal Vitamin A administration with surfactant for newborn respiratory distress syndrome; current st…
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CLINICAL_TRIALS trial_result · 2011-06-22Clinical Trial Update: Comparison of Two Strategies for Surfactant Prophylaxis in Premature Infants [NA]
A clinical trial updating a comparison of two strategies for surfactant prophylaxis in premature infants; trial status is currently unknown.