Renal Transplant Rejection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Simulect Versus ATG in Sensitized Renal Transplant Patient [Phase 4]
Phase 4 trial comparing basiliximab (Simulect) versus antithymocyte globulin (ATG) in sensitized renal transplant patients has completed.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study Comparing Siplizumab With Rabbit Anti-Thymocyte Globulin to Help the Body Accept a Kidney Transplant [Phase 2]
A Phase 2 trial comparing Siplizumab with Rabbit anti-thymocyte globulin to help kidney transplant acceptance; the study is not yet recruiti…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Deep Phenotyping of the Renal Allograft to Prognosticate Clinical Outcomes
A University of Pittsburgh-led clinical study aims to deeply phenotype renal allografts to prognosticate outcomes after kidney transplantati…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: VIRTUUS Children's Study
The VIRTUUS Children's Study (NCT03719339) sponsored by Children's Hospital of Philadelphia is currently active but not recruiting, focusing…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Heme Arginate in Transplantation Study [Phase 3]
A Phase 3 study of Heme Arginate in renal transplantation (rejection and failure) has been terminated.
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Multi-Parametric MRI for Renal Transplantation
This clinical trial update describes a study evaluating multi-parametric MRI for assessing renal transplant rejection.
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Switch to Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/F/TAF) After Renal Transplant [Phase 4]
Phase 4 trial evaluating switching HIV-infected kidney transplant recipients to Bictegravir/emtricitabine/tenofovir alafenamide (Biktarvy). …
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Urine CXCL10 Monitoring Trial in Kidney Transplant [Phase 2, Phase 3]
This clinical trial update describes a Phase 2/3 study evaluating urine CXCL10 monitoring in kidney transplant patients to help detect or pr…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Eliminating the Need for Pancreas Biopsy Using Peripheral Blood Cell-free DNA
A clinical trial update examining whether peripheral blood cell-free DNA can eliminate the need for pancreas biopsy in transplant patients, …
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Fostamatinib in the Treatment of Chronic Active Antibody Mediated Rejection [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating fostamatinib for chronic active antibody-mediated rejection in renal transplant patients is currently …
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: AlloSure for the Monitoring of Antibody Mediated Processes After Kidney Transplantation
A completed clinical trial evaluating AlloSure for monitoring antibody-mediated processes after kidney transplantation.
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FDA approval · 2024-08-13FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (VistaPharm, LLC)
FDA approves a supplemental application for mycophenolate mofetil (VistaPharm, LLC), endorsing a generic product for prevention of organ tra…
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Envarsus on the Effect of Total Tacrolimus Dose/Trough Level Ratio on Renal Function (eGFR) in Kidney Transplantation [Phase 4]
Phase 4 study evaluating whether the ratio of total tacrolimus dose to trough level with Envarsus affects renal function (eGFR) in kidney tr…
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CLINICAL_TRIALS trial_result · 2023-09-05Clinical Trial Update: Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies [Phase 3]
Phase 3 clinical trial evaluating induction therapy in sensitized kidney transplant recipients without pre-existing donor-specific antibodie…
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FDA approval · 2023-05-09FDA Approved: MYCOPHENOLIC ACID — Supplemental Application (Ascend Laboratories, LLC)
FDA approved Ascend Laboratories' supplemental application for mycophenolic acid, authorizing continued marketing of this generic product.
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: Extended Release Tacrolimus vs. Twice-Daily Tacrolimus [Phase 3]
Phase 3 trial comparing extended-release tacrolimus to twice-daily tacrolimus in renal transplant patients; results posted after completion.
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CLINICAL_TRIALS trial_result · 2023-03-06Clinical Trial Update: Contrast Enhanced Ultrasonography to Detect Human Renal Transplant Rejection [Phase 2]
Phase 2 clinical trial evaluating contrast-enhanced ultrasonography for detecting renal transplant rejection has been completed.
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CLINICAL_TRIALS trial_result · 2022-12-13Clinical Trial Update: Mechanisms of Belatacept Effect on Alloimmunity and Antiviral Response After Kidney Transplantation (BMS IM 103-309) [Phase 4]
Phase 4 trial update exploring how belatacept modulates alloimmune and antiviral responses after kidney transplantation, with completed stat…
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CLINICAL_TRIALS trial_result · 2022-01-18Clinical Trial Update: Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients [Phase 3]
A Phase 3 trial evaluating human plasma-derived C1-esterase inhibitor as add-on therapy to standard of care for refractory antibody-mediated…
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: Tacrolimus After rATG and Infliximab Induction Immunosuppression (RIMINI) [Phase 2]
Phase 2 trial update examining tacrolimus after rATG and infliximab induction immunosuppression for renal transplant rejection has completed…
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CLINICAL_TRIALS trial_result · 2020-09-17Clinical Trial Update: Mesenchymal Stromal Cell Therapy in Renal Recipients [Phase 2]
Phase 2 trial update of mesenchymal stromal cell therapy for renal transplant rejection and fibrosis in renal recipients.
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CLINICAL_TRIALS trial_result · 2020-04-14Clinical Trial Update: Steroid Withdrawal and Donor-specific Anti-HLA Antibodies in Renal Transplant Patients [Phase 4]
Phase 4 trial update on steroid withdrawal and donor-specific anti-HLA antibodies in renal transplant patients; completed with results poste…
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FDA approval · 2019-11-22FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Strides Pharma Science Limited)
The FDA approved a supplemental application for mycophenolate mofetil submitted by Strides Pharma Science Limited, enabling regulatory updat…
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CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant [Phase 4]
Phase 4 clinical trial evaluating cytokines in early withdrawal of calcineurin inhibitors for renal transplant patients has completed with r…
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CLINICAL_TRIALS trial_result · 2019-05-31Clinical Trial Update: Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft Recipients [Phase 4]
Phase 4 randomized trial evaluating conversion strategies for calcineurin inhibitors in renal transplant recipients; results posted in 2019.