Renal Impairment
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2) [Phase 1, Phase 2]
A dual-phase clinical trial evaluating how tadalafil (Cialis) affects renal function during volume expansion in preclinical systolic cardiom…
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CLINICAL_TRIALS trial_result · 2020-05-21Clinical Trial Update: A Randomized Clinical Trail of The Effect of Postoperative Uric Acid Control on Stone Recurrence and Renal Function in Patients With Hyperuricemia of Urolithiasis. [Phase 4]
A Phase 4 randomized trial evaluating the effect of postoperative uric acid control on stone recurrence and renal function in patients with …
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CLINICAL_TRIALS trial_result · 2020-05-21Clinical Trial Update: Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3) [Phase 1, Phase 2]
A completed Phase 1/2 trial assessing how tadalafil (Cialis) affects renal function in response to volume expansion in preclinical diastolic…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Renal Function or With Severe Renal Impairment [Phase 1]
Phase 1 pharmacokinetics study evaluating lemborexant and its metabolites in subjects with normal renal function or severe renal impairment …
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: Study to Compare a Dose of Telotristat Etiprate in Subjects With Renal Impairment With Matched Subjects With Normal Renal Function [Phase 1]
Phase 1 trial comparing a dose of telotristat etiprate in subjects with renal impairment to matched controls with normal renal function has …
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CLINICAL_TRIALS trial_result · 2019-05-07Clinical Trial Update: Renal Perfusion, Filtration and Oxygenation During Cardiopulmonary Bypass (CPB)
A completed clinical trial evaluating renal perfusion, filtration, and oxygenation during cardiopulmonary bypass.
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: Pharmacokinetics (PK) and Safety of a Single Intravenous (IV) Dose of MK-3866 in Participants With Impaired Renal Function and in Healthy Controls (MK-3866-005) [Phase 1]
Phase 1 pharmacokinetics and safety study of a single IV dose of MK-3866 in participants with renal impairment and healthy controls has comp…
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CLINICAL_TRIALS trial_result · 2019-03-18Clinical Trial Update: Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function [Phase 4]
Phase 4 trial updating neurotoxic adverse effects of morphine and oxycodone in terminal patients with diminished renal function; study termi…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Study of PK/PD, Safety and Tolerability of LIK066 in Patients With Decreased Renal Function. [Phase 2]
Phase 2 trial evaluating PK/PD, safety and tolerability of LIK066 in patients with decreased renal function has been completed with results …
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CLINICAL_TRIALS trial_result · 2018-12-21Clinical Trial Update: Study of CS-3150 in Combination With ARB or ACE Inhibitor in Hypertensive Patients With Moderate Renal Impairment [Phase 3]
A Phase 3 study evaluating CS-3150 in combination with an ARB or ACE inhibitor for hypertension in patients with moderate renal impairment h…
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography [Phase 4]
A Phase 4 clinical trial investigating the effects of contrast media on subjects with stable reduced renal function undergoing contrast-enha…
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Enoxaparin 20mg Versus 30mg Subcutaneously Once Daily in Elderly Patients With Impaired Renal Function [Phase 4]
Phase 4 trial comparing enoxaparin 20 mg versus 30 mg subcutaneously once daily in elderly patients with renal impairment for venous thrombo…
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Intravenous Fluids After Laparoscopic Cholecystectomy [NA]
This clinical trial update reports the completion of a study evaluating intravenous fluids after laparoscopic cholecystectomy, with outcomes…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011) [Phase 1]
Phase 1 study of MK-7145 in participants with renal impairment and heart failure with renal impairment was terminated; results posted in 201…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: Comparative Evaluation of Pharmacokinetics After CKD-501 Between Renal Impaired and Normal Renal Function Subjects [Phase 1]
Phase 1 pharmacokinetic comparison of CKD-501 in subjects with renal impairment versus healthy controls to assess the impact of kidney funct…
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: The CASABLANCA Study: Catheter Sampled Blood Archive in Cardiovascular Diseases
The CASABLANCA study (Catheter Sampled Blood Archive in Cardiovascular Diseases) has completed status in the clinical trials registry. It in…
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CLINICAL_TRIALS trial_result · 2016-08-26Clinical Trial Update: A Single-dose Study to Investigate the Pharmacokinetics of Intravenous FEP-TAZ in Patients With Renal Impairment [Phase 1]
Phase 1, single-dose pharmacokinetic study of intravenous FEP-TAZ in patients with renal impairment has completed.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: The Pharmacokinetics of Grazoprevir (MK-5172) and Elbasvir (MK-8742) in Participants With Renal Insufficiency (MK-5172-050) [Phase 1]
Phase 1 pharmacokinetic study evaluating grazoprevir and elbasvir in participants with renal impairment.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Safety of Gadovist in Renally Impaired Patients [Phase 4]
A Phase 4 study evaluated the safety of Gadovist (gadobutrol) in patients with renal impairment, and the trial status is completed.
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CLINICAL_TRIALS trial_result · 2015-08-26Clinical Trial Update: EVP-6124 Renal Impairment Study [Phase 1]
FORUM Pharmaceuticals completed a Phase 1 renal impairment study of EVP-6124 (encenicline) under NCT01984723.
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CLINICAL_TRIALS trial_result · 2015-05-22Clinical Trial Update: Fluid Investigation Colloid vs Crystalloid Reg. Renal Hemodynamics and Function [NA]
A completed clinical trial comparing colloid versus crystalloid fluids for effects on renal hemodynamics and kidney function in patients wit…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment [Phase 4]
Phase 4 trial evaluating daptomycin safety and efficacy for complicated skin and skin structure infections and bacteremia in patients with r…
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CLINICAL_TRIALS trial_result · 2015-02-10Clinical Trial Update: Pharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105) [Phase 1]
Phase 1 pharmacokinetics study of sugammadex (MK-8616) in participants with moderate to severe renal insufficiency completed, with results p…
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CLINICAL_TRIALS trial_result · 2014-12-10Clinical Trial Update: Effects of THW and rhTSH in Glomerular Filtration Rate During RIT [NA]
A completed trial from University of Sao Paulo General Hospital evaluated the effects of thyroid hormone withdrawal (THW) and recombinant hu…
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: A Single Centre Open Label Comparison of [I-123]-Ortho-Iodohippuric Acid (OIH) With [Tc-99m]-Mercaptoacetyltriglycine (MAG3) for Assessment of Renal Tubular Function
This clinical trial update reports an open-label, single-centre comparison of I-123 Ortho-Iodohippuric Acid (OIH) and Tc-99m Mercaptoacetylt…