Renal Impairment
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes [NA]
A clinical trial is recruiting for a Renal Assist Device intended to improve renal outcomes in patients with renal impairment after cardiac …
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: A Study of RG002C0106 Injection in Adult Participants With Normal Renal Function and Mild-to-Moderate Renal Impairment [Phase 1]
Phase 1 study of RG002C0106 injection in adults with normal renal function and mild-to-moderate renal impairment; the trial is not yet recru…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Assessment of Renal Function by Multiparametric MRI [EARLY_Phase 1]
Results from an EARLY Phase 1 clinical study assessing renal function using multiparametric MRI.
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls [Phase 1]
A Phase 1 trial update for S-892216-PO in participants with renal impairment and matched controls, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control Subjects With Normal Renal Function [Phase 1]
This Phase 1 study evaluated pharmacokinetics, safety, and tolerability of six days of 100 mg resmetirom in adults with severe renal impairm…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: AZD3427 Effects on Renal Perfusion in Heart Failure Patients With Reduced Ejection Fraction and Renal Impairment [Phase 1]
A Phase 1 trial of AZD3427 evaluating renal perfusion in patients with heart failure with reduced ejection fraction and renal impairment was…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: A Clinical Study of Enlicitide in Participants With Severe Renal Impairment (MK-0616-032) [Phase 1]
A Phase 1 study of Enlicitide (MK-0616-032) in healthy participants and in individuals with severe renal impairment has completed.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: A Study to Evaluate the Drug Levels of Mezigdomide in Adult Participants With Renal Impairment [Phase 1]
A Phase 1 clinical trial update reports pharmacokinetic data for mezigdomide in adults with renal impairment.
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: A Study of Belzutifan (MK-6482) in Participants With Renal Impairment (MK-6482-021) [Phase 1]
Phase 1 study of Belzutifan (MK-6482) in participants with renal impairment (MK-6482-021) has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Phase 1 Study of PK and Safety of HM15912 (Sonefpeglutide) in Subjects With Normal and Severe Kidney Function [Phase 1]
Phase 1 pharmacokinetics and safety study of HM15912 (Sonefpeglutide) in subjects with normal and severe kidney function has completed with …
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Renal Impairment Compared to Healthy Participants. [Phase 1]
A Phase 1 pharmacokinetic study assessing the plasma concentration of tolebrutinib in adults with renal impairment compared with healthy par…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes
The study aims to develop a biomarker panel to predict acute kidney injury earlier in people with diabetes. It is currently recruiting, spon…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Study of GBT021601 in Participants With Renal Impairment [Phase 1]
Pfizer's Phase 1 study of GBT021601 in participants with renal impairment has been terminated.
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Gla-300 and IDeg-100 in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment [Phase 4]
Phase 4 trial evaluating insulin glargine 300 U/mL (Gla-300) and insulin degludec 100 U/mL (IDeg-100) in insulin-naïve adults with type 2 di…
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: A Study to Learn How the Body Processes the Study Medicine Called PF-07923568 in People With Loss of Kidney Function [Phase 1]
Pfizer conducted a Phase 1 pharmacokinetics study of PF-07923568 in individuals with renal impairment to assess how loss of kidney function …
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: A Study to Test How Kidney Problems Influence the Blood Concentrations of Efgartigimod [Phase 1]
Completed Phase 1 pharmacokinetic study evaluating how renal impairment influences blood concentrations of efgartigimod.
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: A Study of Mobocertinib Capsules in People With Severe Kidney Problems and People With Healthy Kidneys [Phase 1]
Phase 1 trial update evaluating mobocertinib capsules in people with severe kidney impairment and in healthy volunteers has completed, with …
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CLINICAL_TRIALS trial_result · 2023-08-22Clinical Trial Update: A Study to Determine the Pharmacokinetics, Pharmacodynamics, and Tolerabiltiy of Betrixaban in Patients With Mild, Moderate, and Severe Renal Impairment [Phase 1]
Phase 1 study investigating pharmacokinetics, pharmacodynamics, and tolerability of betrixaban in patients with varying levels of renal impa…
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CLINICAL_TRIALS trial_result · 2023-08-02Clinical Trial Update: Renal Impairment Study of PF-07321332 Boosted With Ritonavir in Adult Participants With Renal Impairment and in Healthy Participants With Normal Renal Function. [Phase 1]
Phase 1 trial updating renal impairment pharmacokinetics for PF-07321332 boosted with ritonavir in adults with renal impairment and in healt…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Neuromuscular Blockade in Patients With Severe Renal Impairment [Phase 2]
Phase 2 clinical trial evaluating neuromuscular blockade in patients with severe renal impairment has completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Study of a Single Intravenous (IV) Dose of MK-3402 in Participants With Impaired Renal Function and in Healthy Controls (MK-3402-004) [Phase 1]
Phase 1 study of a single IV dose of MK-3402 in participants with renal impairment and healthy controls was terminated; results posted in 20…
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: A Phase 2 Study of Isatuximab in Combination With Bortezomib, Cyclophosphamide and Dexamethasone Followed by Isatuximab and Lenalidomide Maintenance in Newly Diagnosed Patients With Multiple Myeloma and Severe Renal Impairment [Phase 2]
Phase 2 trial of isatuximab with bortezomib, cyclophosphamide, and dexamethasone, followed by maintenance with isatuximab and lenalidomide i…
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CLINICAL_TRIALS trial_result · 2021-05-18Clinical Trial Update: A Renal Impairment Study for PF-06651600 [Phase 1]
Phase 1 renal impairment study of PF-06651600 was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Norepinephrine Infusion Versus Midodrine & Octreotide in Patients With Hepatorenal Syndrome Type 1. [Phase 4]
Phase 4 trial comparing norepinephrine infusion with midodrine and octreotide for hepatorenal syndrome type 1 has completed.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Lorlatinib Renal Impairment Study [Phase 1]
Phase 1 trial update examining lorlatinib in patients with renal impairment; results posted.