Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2024-11-25Clinical Trial Update: Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs
A Travera Inc clinical trial (NCT04985357) evaluating mass response as a biomarker for tumor sensitivity to drugs has been withdrawn; no res…
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CLINICAL_TRIALS withdrawal · 2024-11-25Clinical Trial Update: A Social Support Intervention to Improve Treatment Among Hispanic Kidney and Liver Cancer Patients in Arizona [NA]
This clinical trial evaluating a social support intervention for Hispanic patients with renal cell carcinoma or hepatocellular carcinoma in …
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) [Phase 1, Phase 2]
GI Innovation's GI-102 is being studied in a phase 1/2 trial as a single agent and in combination with pembrolizumab or trastuzumab deruxtec…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: A Study of NDI 1150-101 in Patients With Solid Tumors [Phase 1, Phase 2]
Nimbus Saturn, Inc. is conducting a Phase 1/2 trial of NDI 1150-101 in patients with solid tumors, including renal cell carcinoma, gastric c…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: TIL Therapy for Metastatic Renal Cell Carcinoma [Phase 1]
Phase 1 trial evaluating tumor-infiltrating lymphocyte therapy for metastatic renal cell carcinoma has completed; results were posted on 202…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: A Study of Belzutifan (MK-6482) in Participants With Advanced Clear Cell Renal Cell Carcinoma (MK-6482-018) [Phase 1]
This is a Phase 1 study update of belzutifan (MK-6482) in participants with advanced clear cell renal cell carcinoma. The trial is currently…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for Nephrectomy [Phase 2]
This Phase II trial evaluated Axitinib in patients with clear-cell metastatic renal cell carcinoma unsuitable for nephrectomy and has comple…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Sitravatinib and Nivolumab in Treating Patients With Advanced or Metastatic Kidney Cancer [Phase 1, Phase 2]
Phase 1/2 trial results for the combination of sitravatinib and nivolumab in patients with advanced or metastatic renal cell carcinoma (incl…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors [Phase 1]
Phase 1 study evaluating XL092 as a single-agent and combination therapy for solid tumors, including renal cell carcinoma, hormone receptor-…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell Carcinoma [Phase 1]
Phase I/Ib trial assessing the combination of pembrolizumab with vorinostat in patients with advanced renal cell carcinoma or bladder cancer…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: A CCafU-UroCCR Randomized Trial: 3D Image-Guided Robot-AssisTEd Partial Nephrectomy for Renal Complex Tumor (UroCCR N°99) [NA]
A randomized trial evaluating 3D image-guided robot-assisted partial nephrectomy for renal complex tumors is currently recruiting. No result…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of Pegilodecakin (LY3500518) in patients with advanced solid tumors has completed, spanning multiple indications including mel…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067 [Phase 1, Phase 2]
Phase 1a/Phase 2 study evaluating safety, preliminary efficacy, PK and PD of ST-067 in various cancers; currently recruiting.
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FDA approval · 2024-11-08FDA Approved: PAZOPANIB — Supplemental Application (SUN PHARMACEUTICAL INDUSTRIES, INC.)
FDA approved a supplemental application for pazopanib from Sun Pharmaceutical Industries, Inc. (ANDA 215837).
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: Rapid Sequencing of Approved Therapies in Patients with Metastatic or Unresectable Clear Cell Renal Cell Carcinoma [EARLY_Phase 1]
Clinical trial update announcing recruitment for an early-phase study that rapidly sequences and evaluates approved therapies in patients wi…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: MEDI4736 Combinations in Metastatic Renal Cell Carcinoma [Phase 2]
Phase 2 trial updates the use of durvalumab (MEDI4736) in combinations for metastatic renal cell carcinoma, with the study now completed. Co…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: A Study to Assess the Safety, Pharmacokinetics and Effectiveness of AGS-16C3F Monotherapy in Subjects With Renal Cell Carcinoma (RCC) of Clear Cell or Papillary Histology [Phase 1]
Phase 1 study assessing safety, pharmacokinetics, and preliminary effectiveness of AGS-16C3F as monotherapy in renal cell carcinoma with cle…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types [Phase 1]
A Phase 1 study evaluating MT-8421 as monotherapy and in combination with nivolumab in selected advanced solid tumors has been terminated. T…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Clinical Observation on the Safety and Efficacy of Cardonilmab in the Treatment of Second-line and Above Advanced Melanoma and Advanced Renal Cancer [Phase 2]
A Phase 2 clinical trial update on Cardonilmab for second-line or higher advanced melanoma and advanced renal cancer, focusing on safety and…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: A Study of Avelumab With Axitinib Versus Sunitinib In Advanced Renal Cell Cancer (JAVELIN Renal 101) [Phase 3]
A randomized Phase 3 trial comparing avelumab with axitinib against sunitinib in advanced renal cell carcinoma has completed and posted resu…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Safety and Efficacy of CCT301 CAR-T in Adult Subjects With Recurrent or Refractory Stage IV Renal Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating CCT301 CAR-T therapy in adults with recurrent or refractory stage IV renal cell carcinoma has been ter…
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CLINICAL_TRIALS withdrawal · 2024-10-26Clinical Trial Update: MRI-Guided Radiation Therapy for the Treatment of Early-Stage Kidney Cancer, the MRI-MARK Trial [Phase 2]
Phase 2 trial MRI-MARK evaluating MRI-guided radiation therapy for early-stage renal cell carcinoma has been withdrawn.
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study [NA]
This clinical trial update shows a prospective randomized study comparing erector spinae plane block versus quadratus lumborum block for pos…
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EMA withdrawal · 2024-10-24EMA Withdrawn: Onbevzi (bevacizumab) — Samsung Bioepis NL B.V.
The EMA has withdrawn the marketing authorization for Onbevzi (bevacizumab) by Samsung Bioepis NL B.V., across multiple cancer indications. …
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: A Multimodal Predictive Recurrence Score for Patients With Clear Cell Renal Cell Carcinoma
A clinical trial evaluating a multimodal predictive recurrence score for patients with renal cell carcinoma (clear cell subtype) has complet…