Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma (COBALT-RCC) [Phase 1]
Phase 1 safety and efficacy study of CTX130 in relapsed or refractory renal cell carcinoma (COBALT-RCC) has been terminated.
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Development of AI Model for Renal Tumor Diagnosis Using CT and Lab Tests
A completed clinical trial update from RenJi Hospital describes development of an AI model to diagnose renal tumors using CT imaging and lab…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Efficacy and Safety of Fruquintinib in Combination With Sintilimab in Advanced Renal Cell Carcinoma (FRUSICA-2) [Phase 2, Phase 3]
FRUSICA-2 is evaluating the combination of Fruquintinib and Sintilimab in advanced renal cell carcinoma, currently in Phase 2/Phase 3 with s…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: To Examine the Effects of Axitinib Dose Reduction and Interruption for Adverse Event Management Among Patients Receiving Axitinib in for the Treatment of Advanced Renal Cell Carcinoma
Clinical trial results describe how axitinib dose reductions and temporary interruptions were used to manage adverse events in patients with…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Comparison of Outcomes of Multiple Platforms for Assisted Robotic-Kidney (COMPAR-K) [NA]
A clinical trial entry for COMPAR-K is currently recruiting to compare outcomes across multiple platforms for assisted robotic kidney surger…
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: An Expanded Access Program to Axitinib is Available for Patients With Advanced Forms of Kidney Cancer (Ductal; Papillary; Chromophobic; Oncocytic) With Mutations in VHL, PBRM1 / BAP1, SETD2, VEGF)
An expanded access program for Axitinib in advanced renal cell carcinoma (including tumors with VHL, PBRM1/BAP1, SETD2 mutations) is no long…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Talazoparib and Avelumab in Participants With Metastatic Renal Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating talazoparib plus avelumab in metastatic renal cell carcinoma, including fumarate hydratase–deficient and…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003) [Phase 2]
Phase 2 clinical trial evaluating belzutifan in combination with cabozantinib for clear cell renal cell carcinoma; the MK-6482-003 study is …
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors [Phase 2]
Ipsen-sponsored Phase 2 trial evaluating cabozantinib as second-line treatment for locally advanced or metastatic renal cell carcinoma with …
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: A Study of IBI363 in Subjects with Advanced Solid Malignancies [Phase 2]
Phase 2 study of IBI363 in advanced solid malignancies is currently recruiting, with indications including melanoma, non-small cell lung can…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Fruquintinib and SeRplulimab: Opening New Frontiers in Treating Non-clear Cell Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating Fruquintinib plus SeRplulimab for non-clear renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: A Study Comparing Nivolumab, Nivolumab in Combination With Ipilimumab and Placebo in Participants With Localized Kidney Cancer Who Underwent Surgery to Remove Part of a Kidney [Phase 3]
Phase 3 trial update comparing nivolumab alone or with ipilimumab to placebo in localized renal cell carcinoma after partial nephrectomy; re…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: An Exploratory Study on the Failure of Immunotherapy With Voronib Combined With Everolimus [Phase 2]
This entry notes a Phase 2 exploratory trial of Voronib in combination with Everolimus for renal cell carcinoma. The study is currently recr…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Locally Ablative TherapY in Oligo-ProgressiVe GEnitourinary TumoRs (LAYOVER) [NA]
The LAYOVER trial evaluating locally ablative therapy for oligoprogressive genitourinary tumors is currently recruiting in prostate cancer, …
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Cabozantinib Post First-line Immuno-oncology Checkpoint Inhibitor Containing Combination
Ipsen announces a completed clinical trial evaluating cabozantinib in advanced renal cell carcinoma after first-line immuno-oncology checkpo…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies. [Phase 1]
A Phase I/Ib trial of NZV930 alone and in combination with PDR001 and/or NIR178 in patients with advanced malignancies has been terminated.
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Clinicopathological Features of Renal Cell Carcinoma in Young Patients
Assiut University is planning a clinical study to characterize the clinicopathological features of renal cell carcinoma in young patients, a…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Zero Ischemia Robot-Assisted MWA Assisted Suture-less Tumor Enucleation of RCC With T1 Stage [NA]
This clinical trial update shows recruitment for a zero-ischemia, robot-assisted microwave ablation with suture-less tumor enucleation for r…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Dendritic Cell Vaccination for Patients with Solid Tumors [Phase 1, Phase 2]
Phase 1/Phase 2 clinical study evaluating a dendritic cell vaccine in patients with solid tumors, including glioblastoma and renal cell carc…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Investigation of Differential Biology of Benign and Malignant Renal Masses Using Advanced Magnetic Resonance Imaging Techniques [NA]
University of Cambridge is conducting a study to differentiate benign from malignant renal masses using advanced magnetic resonance imaging …
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CLINICAL_TRIALS other · 2024-12-05Clinical Trial Update: A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma [NA]
A pilot study evaluating a ketogenic diet in combination with nivolumab and ipilimumab for metastatic renal cell carcinoma has been terminat…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: A Study of 3D Visualization Techniques to Improve the Quality and Safety of Robot-assisted Nephron Sparing Surgery for Complex Renal Tumors. [NA]
This clinical trial registry entry describes a study evaluating 3D visualization techniques to improve the quality and safety of robot-assis…
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FDA approval · 2024-12-04FDA Approved: PAZOPANIB — Original Application (Aurobindo Pharma Limited)
FDA approved Aurobindo Pharma Limited's pazopanib ANDA 219034, a generic version of pazopanib. It is indicated for unresectable or metastati…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: CD8 Minibody Repeatability Study [Phase 2]
ImaginAb's Phase 2 CD8 minibody repeatability study in melanoma and renal cell carcinoma has been terminated.
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FDA approval · 2024-11-26FDA Approved: SORAFENIB — Supplemental Application (Dr.Reddys Laboratories Inc)
FDA approved a supplemental application for sorafenib submitted by Dr. Reddy's Laboratories Inc. This action provides supplemental approval …