Renal Allograft Rejection

• CLINICAL_TRIALS trial_result · 2025-05-01
  Clinical Trial Update: Donor-derived Cell-free DNA in Kidney Transplant Recipients

  This clinical trial update reports on donor-derived cell-free DNA in kidney transplant recipients. The study status is completed.

• CLINICAL_TRIALS research · 2024-11-06
  Clinical Trial Update: Study to Compare the Outcome of Receiving Continued Immunosuppression Versus Stopping Immunosuppression at 6 Months to Safely Prevent Human Leukocyte Antigen (HLA) Sensitization in Patients With Late Renal Graft Failure [Phase 4]

  This Phase 4 clinical trial compares continued immunosuppression versus stopping immunosuppression at six months in patients with late renal…

• CLINICAL_TRIALS trial_result · 2023-10-10
  Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney Transplant [Phase 2]

  Phase 2 trial evaluating safety and efficacy of dual costimulation blockade with VIB4920 and belatacept to prevent allograft rejection in ad…

• CLINICAL_TRIALS trial_result · 2020-09-03
  Clinical Trial Update: Single Dose rATG for Renal Allograft Rejection [Phase 4]

  A Phase 4 trial update on single-dose rATG for acute cellular renal allograft rejection; current status is unknown.

• CLINICAL_TRIALS trial_result · 2016-12-29
  Clinical Trial Update: AGe-adapted Benefits of Envarsus Versus Twice-daily Tacrolimus ImmunosuppressioN druGs After Kidney Transplantation [Phase 4]

  Phase 4 trial update comparing Envarsus XR (extended-release tacrolimus) with standard twice-daily tacrolimus in kidney transplant recipient…

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• CLINICAL_TRIALS research · 2015-05-14
  Clinical Trial Update: Genomics of Chronic Renal Allograft Rejection (The GoCAR Study)

  This completed GoCAR trial investigated the genomics of chronic renal allograft rejection in kidney transplant recipients.

• CLINICAL_TRIALS trial_result · 2015-03-18
  Clinical Trial Update: An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simulect for the Prevention of Delayed Graft Function and Acute Allograft Rejection in Renal Allograft Recipients. [Phase 2]

  A Phase II open-label randomized trial comparing Thymoglobulin with Simulect for prevention of delayed graft function and acute rejection in…

• CLINICAL_TRIALS research · 2014-09-25
  Clinical Trial Update: Evaluate Efficacy Study of Combination Therapy of Everolimus and Low Dose Tacrolimus in Renal Allograft Recipients [Phase 4]

  Clinical trial evaluating the combination of everolimus and low-dose tacrolimus in kidney transplant recipients (Phase 4).

• CLINICAL_TRIALS trial_result · 2014-09-18
  Clinical Trial Update: Study Evaluating A Planned Transition From Tacrolimus To Sirolimus In Kidney Transplant Recipients [Phase 4]

  Phase 4 clinical trial update examining a planned switch from tacrolimus to sirolimus in kidney transplant recipients; results were posted i…

• CLINICAL_TRIALS research · 2012-06-25
  Clinical Trial Update: Study to Evaluate Safety and Immunologic Biomarker of Rapamune in Patients With Stable Renal Transplant Recipient [NA]

  A clinical trial update evaluating the safety profile and immunologic biomarkers of Rapamune (sirolimus) in stable renal transplant recipien…

• CLINICAL_TRIALS trial_result · 2009-06-09
  Clinical Trial Update: NI-0401 in Patients With Acute Renal Allograft Rejection [Phase 1, Phase 2]

  This document provides an update on the NI-0401 trial in patients with acute renal allograft rejection, spanning Phase 1 and Phase 2; the st…

• CLINICAL_TRIALS trial_result · 2008-12-12
  Clinical Trial Update: A Safety Clinical Trial of Different Doses of MEDI-507 in the Prevention of Acute Renal Allograft Rejection [Phase 1]

  The document reports results from a Phase 1 safety trial evaluating multiple doses of MEDI-507 to prevent acute renal allograft rejection. T…

• CLINICAL_TRIALS trial_result · 2007-12-27
  Clinical Trial Update: Study Comparing Two Sirolimus Regimens vs. Tacrolimus and Mycophenolate Mofetil Regimen in Kidney Transplant Recipients [Phase 4]

  Phase 4 trial comparing two sirolimus-based regimens with a tacrolimus plus mycophenolate mofetil regimen in kidney transplant recipients to…

• CLINICAL_TRIALS trial_result · 2007-08-02
  Clinical Trial Update: A Study to Compare the Conversion to Prograf® (Tacrolimus) to the Continuation of Cyclosporine in Patients at Risk for Chronic Renal Allograft Failure [Phase 4]

  A Phase 4 clinical trial compares conversion to tacrolimus (Prograf) versus continuation of cyclosporine in kidney transplant patients at ri…