Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study [NA]
A pivotal colorectal cancer device trial (SAFE-2) evaluating the SafeHeal Colovac Colorectal Anastomosis Protection Device was terminated; r…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: A Safety Study Adding Niraparib and Dostarlimab to Radiation Therapy for Rectal Cancers [Phase 1, Phase 2]
This clinical trial update notes termination of a safety study evaluating niraparib and dostarlimab in combination with radiation therapy fo…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Efficacy of Neoadjuvant Folfirinox Regimen in Patients With Resectable Locally Advanced Rectal Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant FOLFIRINOX for resectable locally advanced rectal cancer has completed, reporting efficacy results.
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Non-Operative Management and Early Response Assessment in Rectal Cancer [NA]
An update on a clinical trial evaluating non-operative management and early response assessment in lower rectal adenocarcinoma; the study is…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN) [Phase 2]
Phase 2 trial in rectal cancer evaluating neoadjuvant radiotherapy followed by atezolizumab and bevacizumab. The study is currently active b…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: A Prospective Single Arm Study of Intraoperative Radiotherapy for Locally Advanced or Recurrent Rectal Cancer [Phase 2]
A completed Phase 2 prospective single-arm trial evaluating intraoperative radiotherapy for locally advanced or recurrent rectal cancer.
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer [NA]
A completed clinical trial evaluating the da Vinci Linear Cutting Stapler SureForm in robotic anus-preserving surgery for rectal cancer has …
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Study Using Fluorine-18-Labeled Fluoro-Misonidazole Positron Emission Tomography to Detect Hypoxia in Locally Advanced (T3-T4 and./or N1)Primary Rectal Cancer Patients [NA]
A completed clinical trial evaluated Fluorine-18-labeled fluoro-misonidazole PET imaging to detect tumor hypoxia in locally advanced rectal …
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: A Clinical Evaluation of AI Solutions Developed in the CHAIMELEON Project for Cancer: Prostate, Lung, Breast, Colon and Rectum
Clinical trial update indicating the CHAIMELEON AI solution evaluation for prostate, breast, colon, rectal, and non-small cell lung cancers …
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: LIQUID BIOPSY FOCUSING ON CIRCULATING TUMOR CELLS AND CIRCULATING TUMOR DNA AS PRECISION MEDICINE IN GASTROINTESTINAL TUMORS
A clinical trial update describes using liquid biopsies of circulating tumor cells and circulating tumor DNA to guide precision medicine in …
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting [NA]
This completed clinical trial evaluates whether computer-aided colonoscopy increases detection of neoplasia during colorectal cancer screeni…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Organ Preservation in Early Rectal Cancer Patients [Phase 2]
A Phase 2 clinical trial update evaluating organ-preservation strategies for patients with early rectal cancer, sponsored by Fox Chase Cance…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Clinical Application of PD-1 Inhibitor in Colorectal Cancer for Improving Survival
This update summarizes completed trials assessing a PD-1 inhibitor for colorectal cancer (rectal and colon cancers) with the goal of improvi…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer [Phase 1]
Phase 1 trial evaluating immunotherapy with Y90 radioembolization for metastatic colorectal cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Role of Gut Microbiota in Neoadjuvant Radioimmunotherapy for MSS, Locally Advanced Rectal Cancer
A clinical trial update reports completion of a study evaluating the role of gut microbiota in neoadjuvant radioimmunotherapy for microsatel…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer [Phase 2]
Phase 2 trial evaluating hepatic arterial infusion with floxuridine and dexamethasone, with or without bevacizumab, for hepatic metastases f…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Clinical Relevance of Major Pathologic Regression for Locally Advanced Rectal Cancer
A completed clinical trial update evaluates the clinical relevance of major pathologic regression in locally advanced rectal cancer. It disc…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: the VAPOR-C Trial [Phase 3]
The Phase 3 VAPOR-C trial evaluating volatile anesthesia and perioperative outcomes in cancer patients has been terminated, including colon …
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma (PRECAM) [Phase 2]
Phase 2 PRECAM trial evaluating preoperative short-course radiation followed by Envafolimab plus CAPEOX in microsatellite-stable locally adv…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer [Phase 2]
Phase 2 trial update on an organ-preservation approach for rectal cancer using short-course radiation plus the FOLFOXIRI chemotherapy regime…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases [Phase 2]
Phase 2 study evaluating preoperative chemoradiotherapy with or without induction chemotherapy for rectal cancer with liver metastases has c…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Comprehensive Management of Rectal Cancer
This entry reports the completion of a clinical trial studying comprehensive management of rectal cancer.
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients [Phase 1]
Phase 1 trial evaluating capecitabine-based chemoradiotherapy with the IL-1 receptor antagonist anakinra for rectal cancer has completed. No…
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: Hyperthermia With Chemoradiotherapy in Rectal Cancer [NA]
A clinical trial is currently recruiting to evaluate the combination of hyperthermia with chemoradiotherapy in rectal cancer.
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer [Phase 1]
A Phase 1 study of the live biotherapeutic GB104 in colorectal cancer has completed.