Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION) [Phase 3]
A Phase 3 trial (UNION) is evaluating short-course radiotherapy followed by neoadjuvant chemotherapy and camrelizumab for locally advanced r…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide [EARLY_Phase 1]
First-in-human Phase 1 PET imaging study of the 18F-αvβ6-binding peptide, a radiotracer targeting αvβ6, is active but not currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression [Phase 2]
Phase 2 trial of neoadjuvant mFOLFOX plus Alvenor for locally advanced rectal cancer. The study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers [Phase 1]
The first-in-human Phase 1 study of ATX-559, an oral DHX9 inhibitor from Accent Therapeutics, has been terminated; the trial included patien…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Pilot Study of Individualized Comprehensive Rehabilitation in Patients With Colorectal Cancer [NA]
A pilot study evaluating individualized comprehensive rehabilitation for colorectal cancer patients has completed; no results are provided i…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery
A completed clinical trial evaluating indocyanine green fluorescence angiography to aid intraoperative assessment during laparoscopic sigmoi…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: MRA Diameter as a Predictor for LLN Metastasis in Rectal Cancer.
A completed clinical trial (NCT07419516) investigates whether MRA diameter can predict lateral lymph node metastasis in rectal cancer.
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing HPV vaccine PRGN-2009 alone or in combination with anti-PD-L1/TGF-β trap M7824 in several HPV-associated …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Organ Preservation in Rectal Cancer by Dose Escalated MR Guided Adaptive Radiotherapy [Phase 2]
A Phase 2 clinical trial is evaluating dose-escalated MR-guided adaptive radiotherapy for organ preservation in rectal cancer and is current…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Intraoperative Assessment of Distal Resection Margins Using Frozen Section in Mid and Low Rectal Cancer Surgery [NA]
This clinical trial evaluated intraoperative frozen-section assessment of distal resection margins during mid and low rectal cancer surgery;…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study [Phase 2]
Phase 2 results of the TABAsCO study evaluating TAS-102 in combination with irinotecan and bevacizumab for pre-treated metastatic or unresec…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Postoperative Results and Outcomes in Surgical Pelvic Exenteration
Clinical trial update on postoperative results and outcomes in pelvic exenteration for rectal cancer; enrollment is by invitation.
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Effect of ICCAUT Strategy on Postoperative Urinary Dysfunction After Radical Rectal Cancer Surgery [NA]
A completed clinical trial evaluating the ICCAUT strategy for postoperative urinary dysfunction after radical rectal cancer surgery.
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Robotic Natural Orifice Specimen Extraction Surgery Compared to Robotic Assisted Surgery for Median Rectal Cancer [NA]
This update reports the completion of a clinical trial comparing robotic natural orifice specimen extraction surgery to robotic-assisted sur…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer [Phase 1]
Phase 1 clinical trial evaluating a triple combination of regorafenib, ipilimumab, and nivolumab in chemotherapy-resistant microsatellite-st…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery [NA]
Completed clinical trial comparing transversus abdominis plane (TAP) block to epidural anesthesia for pain management in colorectal surgery;…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer [Phase 2]
Phase 2 trial comparing oral cryotherapy with acupressure/acupuncture versus oral cryotherapy alone to prevent oxaliplatin-induced periphera…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Exploring the Predictive Effect of Intestinal and Oral Microbiota on the Efficacy of Neoadjuvant Radiotherapy and Chemotherapy for Locally Advanced Rectal Cancer Based on Machine Learning
This clinical trial update describes a completed study evaluating whether intestinal and oral microbiota can predict the response to neoadju…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: PeLear CCC: Proyecto Latino Contra Cancer Colorrectal [NA]
The PeLear CCC colorectal cancer trial conducted by the University of North Carolina completed and posted results on January 14, 2026.
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: MRI T1 Relaxation Time in Rectal Cancer
This completed trial evaluated MRI T1 relaxation time as an imaging biomarker in rectal cancer, including locally advanced disease. It prese…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluated neoadjuvant chemoradiation therapy combined with immunotherapy for microsatellite-stable ultra-low rec…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers [NA]
An update on a clinical trial evaluating reduced surgical resection extent after neoadjuvant therapy for locally advanced upper rectal and r…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Survivor Choices for Eating and Drinking - Colorectal Cancer [NA]
The UCSF-sponsored clinical trial on Survivor Choices for Eating and Drinking for colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer [Phase 2]
Phase 2 trial update evaluating short-course radiation with TASOX (TAS102 plus oxaliplatin) chemotherapy in operable rectal cancer, with res…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Prevention of Colorectal Cancer Through Multiomics Blood Testing
Completed clinical trial evaluating a multiomics blood test for colorectal cancer prevention; results have been posted.