Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)
This clinical trial update describes the DIAMOND study, which analyzes the distribution of metastatic lymph nodes in colorectal cancer patie…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course Radiotherapy [Phase 2]
A Phase 2 clinical trial is evaluating whether Bergmann Enema can prevent acute radiation enteritis/rectal injury in rectal cancer patients …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study evaluating LY3214996 with cetuximab, alone or in combination with abemaciclib, for unres…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer [Phase 2]
Phase 2 trial evaluating simultaneous integrated boost radiotherapy (SIB-RT) with CAPOX chemotherapy and a PD-1 inhibitor for high-risk rect…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Radiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC [Phase 2]
Phase 2 trial evaluating neoadjuvant therapy for locally advanced rectal cancer using radiotherapy with CAPOX and immune agents iparomlimab …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer
A registered clinical trial evaluating a dynamic multi-omics integration model to predict neoadjuvant therapy response in locally advanced r…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer [NA]
A clinical trial evaluating postoperative anal function after Parks versus Bacon techniques for low rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: RCT of Mobile Apps & FitBit v. Usual Care [NA]
An ongoing randomized trial compares a mobile apps plus FitBit intervention to usual care in patients with pancreatic, gastric, liver, colon…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC [Phase 2]
Phase 2 trial comparing short-course radiotherapy versus long-course radiotherapy followed by a PD-L1 inhibitor plus CAPEOX as total neoadju…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer [NA]
This ClinicalTrials.gov update describes a study evaluating a watch-and-wait strategy in distal rectal cancer that is dMMR/MSI-H and has bee…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC) [NA]
A clinical trial is evaluating a NEAAR medical food in combination with total neoadjuvant therapy for locally advanced rectal cancer; the st…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Adaptive Radiation Boost for Rectal Cancer [Phase 1]
A Phase 1 clinical trial evaluating an adaptive radiation boost approach for rectal cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer
A clinical trial evaluating the use of multimodal MRI to grade histology and assess prognosis in rectal cancer; status is not yet recruiting…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer
The document updates a clinical trial evaluating neoadjuvant dostarlimab for dMMR/MSI-H locally advanced rectal cancer and notes that the st…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer [NA]
A recruiting study comparing conventional neoadjuvant therapy to total neoadjuvant therapy in older adults with locally advanced rectal canc…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum [NA]
Clinical trial evaluating the safety and efficacy of ischemic preconditioning by embolization of the inferior mesenteric artery in surgery f…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Response-adapted Total Neoadjuvant Therapy Guided by Induction Chemotherapy in Early- and Intermediate-risk Low Rectal Cancer for Implementation of a Watch-and-wait Strategy
This clinical trial evaluates response-adapted total neoadjuvant therapy guided by induction chemotherapy for early- and intermediate-risk l…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique) [NA]
A clinical trial investigating whether preserving the superior left colic artery improves vascularization of the descending colon prior to c…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating the combination of Botensilimab and Balstilimab for microsatellite-stable rectal cancer and locally advanc…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer [NA]
A ClinicalTrials.gov entry describes a study evaluating whether Kegel exercises combined with biofeedback therapy can improve bowel function…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET) [Phase 2]
A Phase II basket trial is evaluating Zanidatamab in combination with Tislelizumab for HER2-positive gastrointestinal tumors, including rect…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial [NA]
The PROPEL Trial is a clinical study evaluating preoperative exercise and nutritional optimization to improve perioperative outcomes for pat…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Clinical Study on the Safety and Relationship of Sintilimab Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma [Phase 2]
Phase 2 clinical study evaluating the safety of combining sintilimab with chemotherapy as neoadjuvant treatment for locally advanced rectal …
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Extra-Peritoneal Tunneling Versus Conventional Drain Fixation After Anterior or Low Anterior Resection [NA]
Clinical trial comparing extra-peritoneal tunneling versus conventional drain fixation after anterior or low anterior resection; the study s…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Colon Neoadjuvant FOLFOXIRI Study [Phase 2]
This update describes a Phase 2 trial evaluating neoadjuvant FOLFOXIRI therapy for rectal cancer, sponsored by the Chinese University of Hon…