Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer [Phase 1]
A Phase 1 clinical trial update for SMART TNT in the conservative management of locally advanced rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal
This entry describes a clinical trial evaluating a novel camera to inspect the bowel after removal of polyps or tumors; the study status is …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma [Phase 2, Phase 3]
Clinical trial evaluating tailored management of locally advanced rectal cancer, currently in Phase 2/3 and recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery [NA]
A clinical trial is evaluating a machine learning-based surgical guidance system for robot-assisted rectal cancer surgery. The study is curr…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Improving Care for Rural Patients With Solid Tumors [NA]
Clinical trial update from University of Colorado focusing on improving care for rural patients with solid tumors; the study is currently re…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Evaluation of Gynecological and Sexual Sequelae
The trial investigates gynecological and sexual sequelae in rectal cancer patients. Recruitment has not yet started.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study) [Phase 2]
A Phase 2 trial (FIRM02) is evaluating neoadjuvant mFOLFOX6 chemotherapy combined with an anti-PD-1 therapy in MSS/pMMR locally advanced rec…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: CAPOX and Bevacizumab With or Without Primary Tumor Radiotherapy and Iparomlimab and Tuvonralimab as First-line Treatment for RAS-Mutant/MSS Metastatic Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating CAPOX and Bevacizumab with or without primary tumor radiotherapy, plus iparomlimab and tuvonralimab, as …
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: XELOX Plus DoSTARlimab Versus XELOX Alone as Consolidation Treatment After Standard Chemoradiation in pMMR/MSS or MSI-Low Locally Advanced Rectal Cancer (LARC) Patients [Phase 2]
Phase 2 clinical trial evaluating XELOX plus Dostarlimab vs XELOX alone as consolidation after chemoradiation in pMMR/MSS or MSI-Low locally…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer [Phase 3]
This Phase 3 trial compares preoperative FOLFOX chemotherapy to postoperative risk-adapted chemotherapy in patients with locally advanced re…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors [Phase 1, Phase 2]
This entry describes a Phase 1/2 study evaluating the safety, pharmacokinetics, and preliminary effectiveness of GSK4418959 in participants …
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Prospective Single-center Randomized Controlled Trial of Robotic Surgery With Transrectal Resection Specimens (NOSES-IV) and Traditional Assisted Robotic Surgery for the Treatment of High Rectal and Sigmoid Colon Cancer [NA]
A prospective, single-center randomized trial compares NOSES-IV robotic surgery with transrectal specimens to traditional assisted robotic s…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer [NA]
Clinical trial update on the SMART trial evaluating modified single-stapled anastomosis in laparoscopic or robotic low anterior resection fo…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer [Phase 3]
A Phase 3 clinical trial is investigating modulated electro-hyperthermia combined with multimodal therapy for locally advanced rectal cancer…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer [Phase 2]
Phase 2 INNATE trial evaluating immunotherapy during neoadjuvant therapy for locally advanced rectal cancer is currently active but not recr…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Application of Amide Proton Transfer-Weighted Imaging in Predicting Pathological Complete Response After Neoadjuvant Therapy of Rectal Cancer
This ClinicalTrials.gov entry describes a study evaluating amide proton transfer-weighted imaging to predict pathological complete response …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating total neoadjuvant therapy with modified FOLFOX (5-fluorouracil, leucovorin, oxaliplatin) and short-cours…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: The Impact of Probiotic Intervention on the Gut Microbiota and Bowel Function [NA]
A clinical trial is evaluating whether a probiotic intervention affects gut microbiota and bowel function in patients with Rectal cancer; th…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer [NA]
An ongoing single-arm multicenter trial is evaluating preoperative neoadjuvant mFOLFOX6 chemotherapy in combination with a PD-1 monoclonal a…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer [NA]
A clinical trial from Peking University Cancer Hospital & Institute is exploring autologous probiotic transplantation in rectal cancer patie…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable) [NA]
KU Leuven is conducting a clinical trial to develop personalized care pathways for bowel symptoms in rectal cancer patients, including Low A…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: F-Tryptophan PET/CT in Human Cancers [Phase 1]
A Phase 1 study evaluating F-Tryptophan PET/CT imaging across several cancers (intracranial glioma, metastatic brain tumor, breast cancer, n…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma
This clinical trial update from Sohag University outlines a study design focused on patterns of treatment and outcomes for locally advanced …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Integrated Cancer Repository for Cancer Research
A University of Nebraska-sponsored clinical trial update indicates the Integrated Cancer Repository for Cancer Research is currently recruit…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial [Phase 1, Phase 2]
Clinical STOPTRAFFIC-1 trial evaluates SX-682 in combination with Nivolumab for RAS-mutated, MSS unresectable or metastatic colorectal cance…