Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: ONCO-RET: Supervised Resistance Training During Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer [NA]
This clinical trial update covers the ONCO-RET study, which investigates supervised resistance training during total neoadjuvant therapy for…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC [Phase 2]
Phase 2 trial evaluating short-course radiotherapy in total neoadjuvant therapy combined with Enlonstobart for pMMR locally advanced rectal …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial evaluating low-dose radiotherapy to enhance Pucotenlimab plus CAPEOX in mismatch repair-proficient locally advanced rectal can…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of Tucatinib and Trastuzumab in People With Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating the combination of tucatinib and trastuzumab in rectal cancer patients is currently recruiting, includin…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Neoadjuvant mFOLFOXIRI Plus Bevacizumab in Patients With High-Risk Locally Advanced Rectal Cancer [Phase 3]
A Phase 3 clinical trial is evaluating neoadjuvant therapy with mFOLFOXIRI plus bevacizumab in patients with high-risk locally advanced rect…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery [NA]
An ongoing Sun Yat-sen University clinical trial is evaluating pelvic floor peritoneal closure to prevent postoperative ileus after middle-t…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: ColoSeal™ ICD System Anastomotic Protection Pivotal Study [NA]
Clinical trial update for the ColoSeal ICD System Anastomotic Protection pivotal study in rectal cancer surgery, currently not yet recruitin…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: INVESTIGATION OF THE ANTI-NEOPLASTIC EFFECT OF TRISHUL (AYURVEDIC AGENT) ON TUMOUR REGRESSION OF RECTAL CANCER- A PILOT STUDY [Phase 2]
A Phase 2 pilot clinical trial is investigating the anti-tumor effects of the Ayurvedic agent Trishul on rectal cancer, with recruitment not…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Quality Of Life In Colorectal Cancer Survivors [NA]
A clinical trial assessing quality of life in colorectal cancer survivors is currently recruiting at the Institute of Oncology Ljubljana.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of a mesothelin-targeting logic-gated CAR T therapy in adults with solid tumors …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Relationship Between Quality of Life, Treatment Modalities, and Patient Treatment/Outcome Expectations
This clinical trial update describes an ongoing study on rectal cancer examining quality of life, treatment modalities, and patient treatmen…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Advanced Endoscopic Resections for Rectal Neoplasms
This clinical trial update outlines advanced endoscopic resection approaches for rectal neoplasms, and the study is currently not yet recrui…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer [Phase 3]
This ClinicalTrials.gov entry describes a Phase 3 study evaluating early erectile rehabilitation with sildenafil after radiotherapy and proc…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer [Phase 1]
This clinical trial update indicates that Akamis Bio is recruiting for a Phase 1 study of NG-350A in combination with chemoradiotherapy for …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: The Surveillance Nonoperative Watch & Wait (SNOWW) Rectal Cancer Trial.
The SNOWW trial evaluates a nonoperative watch-and-wait approach for rectal cancer, and the trial is currently not yet recruiting. This upda…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: No Surgery Trial / Two Dose-escalation Strategies [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating two dose-escalation strategies for rectal cancer with no surgery, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in High-Risk Locally Advanced Rectal Cancer [Phase 3]
This Phase 3 trial compares long-course radiotherapy followed by total neoadjuvant therapy with immunotherapy versus long-course radiotherap…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer [NA]
A clinical trial update describing the use of ultrasound and photoacoustic imaging to improve differential diagnosis of rectal cancer; the s…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced Rectal Cancer [Phase 2]
Clinical trial update for a Phase 2 study combining preoperative sequential short-course radiation therapy with the FOLFOX regimen in locall…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Phase II Prospective Study of Maastro Applicator Brachytherapy for Rectal Cancer [Phase 2]
This update covers a Phase II prospective study evaluating the Maastro Applicator Brachytherapy for rectal cancer. The study is currently no…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating adding epacadostat to preoperative chemoradiation for locally advanced rectal cancer; recruitment i…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial protocol evaluating short-course radiotherapy combined with chemotherapy and immunotherapy for mid-low locally advanced rect…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial) [NA]
The FEED Trial is investigating a high-fermented food intervention in patients with rectal cancer (also listed for non-small cell lung cance…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating short-course radiotherapy with tumor-draining lymph node preservation followed by a PD-1 inhibitor in pati…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy [Phase 2]
This is a Phase 2 clinical trial evaluating the combination of Botensilimab and Balstilimab for colorectal cancer with detectable ctDNA afte…