Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer [Phase 2]
A Phase 2 clinical trial update evaluating neoadjuvant regorafenib in combination with nivolumab and short-course radiotherapy for stage II–…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases [Phase 2]
Phase 2 clinical trial SCRT-CAPEOX-Serplulimab for MSS/pMMR rectal cancer with oligometastases is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: The Impact of Two-Stage Turnbull-Cutait Pull-Through Coloanal Anastomosis on Stoma-free Survival in Low Rectal Anal-preserving Surgery [NA]
A clinical trial evaluating a two-stage Turnbull-Cutait pull-through coloanal anastomosis to improve stoma-free survival in low rectal cance…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Developing and Testing the Effect of Online Interactive Videos in Improving Low Anterior Resection Syndrome. [NA]
A clinical trial is recruiting to test online interactive videos for improving Low Anterior Resection Syndrome in patients with rectal cance…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Next Generation STAR-TREC (NG-ST) - Organ Preservation in Early Rectal Cancer [Phase 4]
Phase 4 update on the Next Generation STAR-TREC trial evaluating organ preservation in early rectal cancer; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer
A clinical trial evaluating hypofractionated palliative radiotherapy for patients with advanced non-operable rectal cancer is currently recr…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC) [Phase 2]
A Phase 2 clinical trial is evaluating Fruquintinib plus FOLFIRI as second-line therapy for metastatic colorectal cancer and is currently re…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer [NA]
A clinical trial is currently recruiting to assess the response to standard treatment before surgery in people with rectal cancer.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: These Studies Assess Surgeons' Physical and Ergonomic Workloads. Study 1 Compares Laparoscopic vs. Hugo RAS Robotic Approaches for Rectal Resection. Study 2 Compares Hugo RAS vs. Da Vinci Xi for Prostatectomy. Both Track Physiological Stress, Surgical Strain Phases, and Exerted Force. [NA]
A clinical trial update describing two comparative studies on surgical approaches—laparoscopic versus Hugo RAS robotic for rectal resection …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer [Phase 2]
A Phase 2 clinical trial is evaluating sequential TAS-OX alternating with TAS-IRI plus bevacizumab for late-line metastatic colorectal cance…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Resilience and Equity in Aging, Cancer, and Health (REACH) [NA]
The REACH trial sponsored by Dana-Farber Cancer Institute is currently recruiting. It targets multiple gastrointestinal cancers including ga…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating SHR-1701 plus chemoradiotherapy for locally advanced rectal cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC [NA]
An ongoing clinical trial evaluating a regimen of short-course radiotherapy (SCRT) followed by Nal-IRI XELOX and Sintilimab as total neoadju…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial comparing short-course radiotherapy with CAPOX and tislelizumab versus long-course chemoradiation with tislelizumab for loca…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak [Phase 4]
A multicenter randomized Phase 4 trial compares SIS-Reinforced versus conventional anastomosis for mid-to-low rectal cancer. The study aims …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: FOLFIRINOX Induction Chemotherapy for Synchronous Liver Metastases
Clinical trial update describing FOLFIRINOX induction chemotherapy for patients with rectal cancer and synchronous liver metastases; the stu…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation
This clinical trial update outlines a Memorial Sloan Kettering study evaluating cellular changes in colon/colorectal cancer after radioembol…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: REsults of LOw Anterior Resections With or Without Preventive Stoma in Nonemergency Department [NA]
A clinical trial evaluating whether a preventive stoma is needed after low anterior resection for rectal cancer in nonemergency settings; th…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial [NA]
This is a clinical trial update indicating a randomized study on meal timing during cancer treatment in Alaska is currently recruiting, invo…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial evaluating neoadjuvant chemoradiotherapy plus tislelizumab with or without Probio-M9 in mismatch repair-proficient/microsate…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial is evaluating the combination of a PCSK9 inhibitor and a PD-1 inhibitor with neoadjuvant chemoradiotherapy for pMMR/MSS loca…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01） [Phase 2]
A Phase 2 clinical trial (CONTROL-01) is evaluating neoadjuvant chemotherapy with a PD-1 inhibitor for locally advanced rectal cancer, and r…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled, Multicenter Phase II/III Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer [Phase 2, Phase 3]
A Phase II/III randomized trial is evaluating Adebrelimab in combination with SHR-8068 and chemoradiotherapy as perioperative therapy for lo…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer [Phase 2]
This document reports a Phase 2 clinical trial evaluating serplulimab combined with CAPEOX and celecoxib as neoadjuvant therapy for locally …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
The MOMENTUM study is evaluating radiation therapy using an MR-Linac across multiple cancer types and is currently recruiting.