Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial [Phase 2]
This is a Phase II, multi-center randomized trial protocol evaluating neoadjuvant moderately hypofractionated radiotherapy with chemotherapy…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer [Phase 2]
Phase II trial update evaluating camrelizumab with long-course chemoradiotherapy as total neoadjuvant therapy for locally advanced rectal ca…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant CAPOX with or without Pucotenlimab and selective radiotherapy for locally advanced rectal cancer is cur…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer [Phase 3]
A Phase 3 clinical trial comparing neoadjuvant chemotherapy with excision and observation versus chemoradiotherapy for rectal cancer is curr…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Short-Course Radiotherapy, Nal-IRI, Capecitabine, and Camrelizumab for Locally Advanced MSS Rectal Cancer [Phase 2]
Phase 2 trial evaluating short-course radiotherapy in combination with nal-IRI (nanoliposomal irinotecan), capecitabine, and camrelizumab fo…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer [Phase 2]
Clinical Trial Update describes a Phase 2 study evaluating a therapy adapted for high-risk and low-risk HIV-associated anal cancer, with the…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Multidimensional Study Designed to Develop a Methodological Framework Based on MRI Data to Predict Pathological Complete Response (pCR) in Patients With Locally Advanced Rectal Cancer After Neoadjuvant Treatment
This update describes a multidimensional clinical study to develop an MRI-based framework to predict pathological complete response after ne…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial evaluating nivolumab and ipilimumab with short-course radiation for locally advanced rectal cancer; the study is currently act…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin [NA]
Clinical trial evaluating Mepilex Lite dressings for treating acute radiation dermatitis of the anal canal skin in rectal cancer patients un…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy [Phase 1]
This Phase 1 trial update describes evaluating ropidoxuridine as a radiosensitizer in patients with advanced gastrointestinal cancers underg…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Registry Maastro Applicator
Clinical trial registry entry for the Maastro Applicator in rectal cancer, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Total Neoadjuvant Therapy in Rectal Cancer [Phase 2]
A Phase 2 clinical trial is evaluating total neoadjuvant therapy for rectal cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Adaptive Radiotherapy for Safe Hypofractionation [Phase 2]
A Phase 2 clinical trial update describes adaptive radiotherapy to enable safe hypofractionation across several cancers. The study is curren…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients [NA]
The clinical trial NCT07514754 investigating Galenos 2 immunonutrition for head and neck squamous cell carcinoma, locally advanced rectal ca…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Phase 2 Trial Of Sacituzumab Tirumotecan For Treatment Of Refractory Metastatic Or Unresectable Squamous Cell Carcinoma Of The Anus/Rectum [Phase 2]
A Phase 2 clinical trial is evaluating Sacituzumab Tirumotecan for refractory metastatic or unresectable squamous cell carcinoma of the anus…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
The GALENOS 1 trial is currently recruiting for patients with head and neck squamous cell carcinoma, locally advanced rectal cancer, and lun…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer
A clinical trial assessing quality of life and health utility following surgical treatment for stage I through IV rectal cancer, sponsored b…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Intraoperative Rectal Lavage to Prevent Local Recurrence After Laparoscopic Mid-to-Low Rectal Cancer Resection: A Multicenter Randomized Trial [NA]
A multicenter randomized trial is evaluating whether intraoperative rectal lavage can reduce local recurrence after laparoscopic mid-to-low …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates [Phase 2]
Phase 2, single-arm trial evaluating rectal cancer brachytherapy for low-lying residual rectal adenocarcinoma after total neoadjuvant therap…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: CAPOX and PD-1 Antibody Combined With or Without Radiotherapy for MSS Locally Advanced Rectal Cancer [Phase 2]
Phase 2 clinical trial update evaluating CAPOX with a PD-1 antibody, with or without radiotherapy, for MSS locally advanced rectal cancer; c…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Predicting Pathological Complete Response in Rectal Cancer Using Machine Learning
This clinical trial update describes an active-not-recruiting study from Peking University People's Hospital examining machine learning to p…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Clinical and BIOgical Analyses of RECtal Tumors [NA]
Clinical trial update describing clinical and biological analyses of rectal tumors; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps [NA]
NRG Oncology is recruiting for a trial comparing five- vs ten-year colonoscopy intervals in individuals with 1-2 non-advanced adenomatous po…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Without Concurrent Surufatinib in Neoadjuvant Therapy for Mid-to-low Localized Rectal Cancer of High-risk Criteria [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluating neoadjuvant therapy for high-risk mid-to-low localized rectal cancer, comparing short-course radiother…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: MIMICC Study in Patients With Colorectal Cancer [NA]
The MIMICC Study in colorectal cancer is currently recruiting, with conditions including colorectal cancer, colon cancer, and rectal cancer.