Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer [Phase 3]
Phase 3 clinical trial comparing chemotherapy followed by pelvic reirradiation versus chemotherapy alone as pre-operative treatment for loca…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: End to End Anastomosis With Omega Suture Versus End to Anterior Rectal Wall In Colorectal Anastomosis in Sigmoid and Upper Rectal Cancer [NA]
A clinical trial comparing omega-suture end-to-end anastomosis with end-to-end anastomosis to the anterior rectal wall in colorectal surgery…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes an ongoing Phase 1/2 study of CAR-T cells targeting the carcinoembryonic antigen (CEA) for CEA-positive…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Prehabilitation During Neoadjuvant Chemoradiotherapy for Rectal Cancer [NA]
A clinical trial sponsored by Fudan University evaluating prehabilitation during neoadjuvant chemoradiotherapy for rectal cancer has complet…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection [Phase 3]
Phase 3 clinical trial evaluating prophylactic mesh placement during stoma closure after low anterior resection for rectal cancer; currently…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer [Phase 1, Phase 2]
Ongoing Phase 1/2 trial evaluating sintilimab with hypofractionated radiotherapy for MSI-H/dMMR rectal cancer; recruitment is currently open…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer [NA]
A prospective monocentric study is evaluating circulating NK cell phenotype and the ImmunoScore in patients with non-metastatic rectal cance…
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial [NA]
A randomized controlled trial evaluating pelvic rehabilitation after low anterior resection for rectal cancer; the study is not yet recruiti…
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: The Role of Short Course of Palliative Radiation in Metastatic Cancer Rectum [NA]
Clinical trial update indicates a short-course palliative radiation approach for metastatic rectal cancer is not yet recruiting, sponsored b…
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome) [NA]
A clinical trial is ongoing to test whether pelvic floor exercises prevent Low Anterior Resection Syndrome in patients after rectal cancer s…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: SCRT Followed by Camrelizumab Combined With Fluzoparib and Chemotherapy as Neoadjuvant Therapy for LARC [Phase 2]
A Phase 2 clinical trial in colorectal cancer (locally advanced rectal cancer) is recruiting to evaluate SCRT followed by combination therap…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for UCMYM802 Injection in mesothelin-positive advanced malignant solid tumors, listing several cance…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Application of PD-1 Monoclonal Antibody in Combination With IL-2 and CapeOX in Organ Preservation Therapy for Ultra-Low Localized Advanced Rectal Cancer
A planned clinical trial investigates using a PD-1 monoclonal antibody in combination with interleukin-2 and CapeOX chemotherapy for organ p…
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Assessment of Response Before, During and After Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients [NA]
This clinical trial evaluates responses to neoadjuvant chemoradiotherapy in rectal cancer patients, with assessments before, during, and aft…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Transanal Transection and Single-stapled Anastomosis (TTSS) in Rectal Cancer Patients
This clinical trial is evaluating transanal transection and single-stapled anastomosis (TTSS) in rectal cancer patients undergoing surgery a…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Natural Orifice Specimen Extraction in Low Rectal Cancer Surgery
A clinical trial update shows that the study on natural orifice specimen extraction in low rectal cancer surgery is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures [NA]
Clinical trial update indicating that Intuitive Surgical's da Vinci SP IDE study for colorectal procedures is active but not recruiting.
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Short-course Radiotherapy Combined With CAPOX and PD-1 Antibody Versus Long-course Chemoradiotherapy Combined With CAPOX for Early Low-lying Rectal Cancer [Phase 2]
Phase 2 trial comparing short-course radiotherapy with CAPOX plus a PD-1 antibody versus long-course chemoradiotherapy with CAPOX in patient…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers [NA]
A clinical trial update evaluating the reproducibility and repeatability of diffusion-weighted MRI measurements on an MR-Linac for pelvic im…
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CLINICAL_TRIALS research · 2024-06-13Clinical Trial Update: Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE) [Phase 2]
Phase 2 clinical trial assessing short-course radiotherapy with CapeOx and a PD-1 inhibitor after local excision for high-risk early rectal …
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Ttransanal Endoscopic Microsurgery in T1 N0, M0 Rectal Cancer (TAUTEM-T1 Study) [Phase 3]
A Phase 3 clinical trial (TAUTEM-T1) evaluates preoperative chemoradiotherapy plus transanal endoscopic microsurgery versus transanal endosc…
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CLINICAL_TRIALS research · 2024-06-05Clinical Trial Update: Selection of Surgical Technique in Rectal Cancer
This entry notes an ongoing clinical trial evaluating surgical technique selection in rectal cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: MRI Simulation-guided Boost in Short-course Preoperative Radiotherapy for Unresectable Rectal Cancer [Phase 2]
Phase 2 trial investigating MRI simulation-guided boost in short-course preoperative radiotherapy for unresectable rectal cancer; currently …
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer (GRECCAR17) [NA]
GRECCAR17 is a clinical trial comparing tailored versus systematic use of a defunctioning stoma after total mesorectal excision for rectal c…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment
A clinical trial update announcing a study to evaluate local excision as an organ-preserving approach for early rectal cancer without adjuva…