Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Early Rectal Cancer [Phase 2]
This is a Phase 2 clinical trial update describing the investigation of combining immunotherapy with neoadjuvant short-course radiotherapy f…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer [Phase 2]
A Phase 2 trial is evaluating nodes-sparing short-course radiation combined with CAPOX chemotherapy and tislelizumab for microsatellite-stab…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. [Phase 2, Phase 3]
Phase 2/3 clinical trial comparing total neoadjuvant therapy with organ preservation versus surgery for rectal cancer; recruitment is ongoin…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial of Adebrelimab (PD-L1) with short-course radiotherapy and chemotherapy as neoadjuvant treatment for locally advanced rectal ca…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 clinical trial examining short-course radiotherapy followed by CAPOX chemotherapy and Ivonescimab for locally advanced rectal cancer…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer [Phase 2]
A Phase 2 trial to evaluate preoperative chemoradiotherapy combined with toripalimab for locally recurrent rectal cancer; the study is curre…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer
This entry updates a clinical trial evaluating how long PD-1 neoadjuvant therapy should be given for stage II-III mismatch repair-deficient …
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial evaluating a circulating tumor DNA-guided neoadjuvant treatment strategy for locally advanced rectal cancer is currently rec…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: A Prospective Study of Expression Profiling-based Assessment of the Efficacy of Neoadjuvant Therapy for Rectal Cancer
This clinical trial update describes a prospective study using expression profiling to assess the efficacy of neoadjuvant therapy for rectal…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: External Beam Radiotherapy Combined with Endorectal High-dose-rate Brachytherapy in Elderly and Frail Patients with Rectal Cancer [NA]
This clinical trial investigates external beam radiotherapy combined with endorectal high-dose-rate brachytherapy for rectal cancer in elder…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC [Phase 2]
A Phase 2 trial evaluating short-course radiotherapy followed by neoadjuvant chemotherapy with HLX07 and serplulimab in locally advanced rec…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: PRediction of Outcomes and PERsonalized Radiotherapy by Biomarkers and Functional Imaging [NA]
This entry describes an ongoing clinical trial investigating biomarkers and functional imaging to predict outcomes and personalize radiother…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Total Neoadjuvant Treatment of Rectal Cancer by MRI-guided Radiotherapy
This clinical trial entry notes an ongoing investigation of total neoadjuvant treatment for rectal cancer using MRI-guided radiotherapy, cur…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Neoadjuvant Radiotherapy Before Surgery for Rectal Cancer, Surgical and Oncological Outcome Analysis, Retrospective Case Control Study in a Single Institute.
A retrospective case-control study from a single institute evaluates surgical and oncological outcomes of neoadjuvant radiotherapy before su…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Spanish Registry of Digestive Tumours RETUD
This entry notes the RETUD Spanish registry for digestive tumours is currently recruiting, sponsored by the Spanish Cooperative Group for th…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Study of the Prevalence of Sexual Dysfunction in Women After Rectal Cancer Surgery and Analysis of the Impact of a Sexologist Intervention [NA]
This ClinicalTrials.gov study investigates how common sexual dysfunction is in women after rectal cancer surgery and evaluates the impact of…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait [NA]
A clinical trial is evaluating chemoradiation with consolidation chemotherapy, with or without oxaliplatin, for distal rectal cancer and a w…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Artificial Intelligence Assists Surgeons' Decision Making [NA]
This clinical trial update reports a study evaluating an artificial intelligence–assisted decision-support system to aid surgeons in rectal …
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Non-operative Management for Locally Advanced Rectal Cancer [NA]
A clinical trial is currently recruiting to evaluate non-operative management for locally advanced rectal cancer.
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Asian Watch-and-Wait Database (AWWD)
A clinical trial update for the Asian Watch-and-Wait Database (AWWD) sponsored by Tata Memorial Centre for rectal cancer/rectal adenocarcino…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: To Evaluate Dose and Safety of NanoEcho Particle-1 Using NanoEcho Imaging Device Examinations of Rectal Lymph Nodes in Healthy Volunteers and Rectal Cancer Patients. [Phase 2]
Phase 2 clinical trial evaluating the dose and safety of NanoEcho Particle-1 with the NanoEcho Imaging Device for examinations of rectal lym…
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CLINICAL_TRIALS research · 2024-11-13Clinical Trial Update: Longterm Functional Outcomes in Patients Undergoing Organ Preserving Treatment for Rectal Cancer With or Without Local Excision After Chemoradiotherapy
Clinical trial update describing a study that will assess long-term functional outcomes of organ-preserving treatment for rectal cancer, wit…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing biological tumor-infiltrating lymphocytes therapy combined with immunotherapy for colorectal cancer is cu…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer [NA]
Ongoing clinical trial evaluating drug sensitivity detection of micro tumor (PTC) to guide postoperative adjuvant treatment in colorectal ca…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery [NA]
This clinical trial update from Imperial College London investigates using pre-therapeutic MRI to guide treatment for early-stage rectal can…