Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer [Phase 2]
Phase 2 clinical trial of neoadjuvant chemoradiation with Nal-IRI and capecitabine guided by UGT1A1 status in rectal cancer; currently recru…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Adaptive Boost Radiotherapy to Primary Lesions and Positive Nodes in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer
Clinical trial evaluating adaptive boost radiotherapy to primary rectal lesions and positive lymph nodes as part of neoadjuvant treatment fo…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III) [Phase 3]
A multicenter, randomized Phase III trial evaluating short-course radiotherapy followed by Cadonilimab plus MFOLFOX6 as neoadjuvant therapy …
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Neoadjuvant Therapy for Locally Advanced Rectal Cancer [EARLY_Phase 1]
This document provides a clinical trial update for neoadjuvant therapy in locally advanced rectal cancer. The trial is at EARLY Phase 1, spo…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: the Effect of Environmental Factors on Colorectal Cancer Based on Macrogenomes
A clinical trial exploring how environmental factors influence colorectal cancer using macrogenome data; currently not recruiting.
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: DataBase for Analysis of Rectal Cancer Oncological Results
Completed update of a clinical trial database analyzing rectal cancer oncological outcomes, with metformin as a condition of interest and en…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: MR-guided Adaptive Radiotherapy Combined With PD-1 Antibody and CAPOX for Locally Advanced Rectal Cancer [Phase 2]
This Phase 2 trial evaluates MR-guided adaptive radiotherapy combined with a PD-1 antibody and CAPOX chemotherapy for locally advanced recta…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Neoadjuvant FOLFIRINOX and Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer Patients [Phase 2]
Phase 2 trial evaluating neoadjuvant FOLFIRINOX combined with preoperative chemoradiotherapy for locally advanced rectal cancer is currently…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: RATME Vs LATME in Middle and Low Rectal Cancer [NA]
A clinical trial comparing RATME versus LATME surgical techniques for middle and low rectal cancer, currently not recruiting.
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: PRODIGE 90 - (FFCD 2204) Neoadjuvant Dostarlimab with Short Course Radiotherapy in a Watch-and-wait Strategy for Microsatellite Unstable or Mismatch Repair-deficient Locally Advanced Rectal Cancer Patients [Phase 3]
Phase 3 trial evaluating neoadjuvant dostarlimab with short-course radiotherapy in a watch-and-wait strategy for mismatch repair-deficient o…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment
This clinical trial update covers results from a study evaluating the financial burden on patients with Stage I-III colon or rectal cancer u…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Development of a Clinical and Biological Database in Rectum Cancer [NA]
Development of a clinical and biological database for rectal neoplasms is underway, with the study currently recruiting. The sponsor is Inst…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Advances in Imaging to Assess Response in Rectal Cancer
This clinical trial update describes advances in imaging techniques to assess treatment response in rectal cancer and notes that the study i…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Liquid Biopsies and IMAging for Improved Cancer Care [NA]
A clinical trial update from Institut du Cancer de Montpellier - Val d'Aurelle describes a study on liquid biopsies and imaging to improve r…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Rectal Surgery Evaluation Trial (RESET)
The Rectal Surgery Evaluation Trial (RESET) has completed.
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Determination of Microbiological Factors Associated With Poor Response to Neoadjuvant Treatment in Rectal Cancers [NA]
This clinical trial update describes a study investigating microbiological factors linked to poor response to neoadjuvant treatment in recta…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: To Explore the Efficacy of Sintilimab Combined With Bevacizumab in Rectal Cancer [Phase 2]
Phase 2 clinical trial registry entry evaluating the efficacy of combining sintilimab with bevacizumab in rectal cancer, currently recruitin…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer [EARLY_Phase 1]
This entry describes an EARLY Phase 1 clinical trial evaluating whether structured exercise can improve the effectiveness of long-course che…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Image-Guided Surgery In The Treatment Of Rectal Cancer (AR_CRC) [NA]
A clinical trial (AR_CRC) evaluating image-guided surgery for rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 clinical trial is evaluating antibiotics to modulate the intestinal microbiome as part of neoadjuvant treatment for locally advanc…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal Malignancies
Viome's completed clinical trial update reports analyses of the intestinal microbiome, oral microbiome, and whole-blood transcriptome across…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Transanal Irrigation for Low Anterior Resection Syndrome [NA]
Clinical trial evaluating transanal irrigation to treat Low anterior resection syndrome in patients following rectal cancer surgery; the stu…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients [Phase 1, Phase 2]
A Phase 1/2 trial is planned to evaluate adjunctive rifaximin for preventing radiotherapy-induced diarrhea in cancer patients, including pro…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: CLASSICA: Validating AI in Classifying Cancer in Real-Time Surgery
A clinical trial update for CLASSICA, evaluating AI to classify cancer in real-time during rectal surgery, currently recruiting.
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer [NA]
This document reports an ongoing clinical trial comparing transanal with laparoscopic total mesorectal excision for rectal cancer, with pati…