Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Immunotherapy in Patients With Early dMMR Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating immunotherapy for patients with early dMMR rectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: ADAR1 Expression Level in Rectal Cancer
A recruiting clinical trial at Necmettin Erbakan University is investigating ADAR1 expression levels in rectal cancer.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Study On The Prediction of Neoadjuvant Efficacy For Rectal Cancer Based On MR Cytometry Imaging and Deep-radiomics
Clinical trial evaluating whether MR cytometry imaging and deep radiomics can predict neoadjuvant treatment efficacy in rectal cancer. The s…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Efficacy and Safety of Trastuzumab Biosimilars and Pertuzumab Biosimilars Combined With Chemotherapy for Neoadjuvant Treatment of Patients With Locally Advanced HER2-positive Rectal Cancer [Phase 2]
Phase 2 clinical trial evaluating trastuzumab biosimilars and pertuzumab biosimilars with chemotherapy as neoadjuvant therapy for locally ad…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY)
A trial update for the CROSS study investigating low stable pressure pneumoperitoneum in colorectal surgery is currently recruiting patients…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Endorectal Brachytherapy for Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating endorectal brachytherapy for locally advanced rectal cancer has been suspended.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer Patients [Phase 2]
A Phase 2 trial evaluating total neoadjuvant sandwich treatment via short-course radiotherapy for stage II/III rectal cancer. The study is c…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: A Prospective Feasibility Study Evaluating Extracellular Vesicles Obtained by Liquid Biopsy for Neoadjuvant Treatment Response Assessment in Rectal Cancer
A prospective feasibility study evaluating extracellular vesicles from liquid biopsy to assess neoadjuvant treatment response in rectal canc…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Perioperative Treatment With TAS-102 in Combination With Oxaliplatin for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 study evaluating perioperative TAS-102 in combination with oxaliplatin for locally advanced rectal cancer, focusing on event-free su…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Transanal Irrigation for the Management of LARS [NA]
This document reports an active-not-recruiting clinical trial at Jewish General Hospital evaluating transanal irrigation for managing Low An…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer [NA]
This clinical trial update indicates recruitment is ongoing for the ROBIN Molecular Characterization Trial of Standard Short Course Radiothe…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: DETECT: Target Volume for Rectal Endoluminal Radiation Boosting
This clinical trial entry describes DETECT, a study evaluating target volume for rectal endoluminal radiation boosting in rectal cancer, cur…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Irinotecan Liposomes in Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer [Phase 3]
A Phase 3 trial evaluating irinotecan liposome-based total neoadjuvant therapy for locally advanced rectal cancer, sponsored by Zhejiang Can…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer. [Phase 2]
Phase 2 clinical trial evaluating total neoadjuvant therapy with or without tislelizumab for locally advanced rectal cancer; currently recru…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal Cancer [NA]
A clinical trial investigating MR-guided online adaptive radiotherapy for locally advanced rectal cancer. The study is currently not recruit…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit) [NA]
A UCSF-sponsored clinical trial called 'Tools To Be Fit' aims to improve nutrition and physical activity among cancer survivors and is curre…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial [Phase 1]
The DINOMITE Phase 1 trial is evaluating papaverine in combination with radiation therapy for locally advanced rectal cancer and is currentl…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Planed Organ Preservation for Low Rectal Cancer After Neoadjuvant Chemotherapy (OPLAR) [Phase 3]
A Phase 3 clinical trial (OPLAR) evaluating organ preservation for low rectal cancer after neoadjuvant chemotherapy; currently recruiting at…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer [Phase 3]
Phase 3 trial comparing 2 vs 4 cycles of neoadjuvant CAPOX for low/intermediate risk II/III rectal cancer; current status is active but not …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) [NA]
A Washington University School of Medicine trial (WU-PE-CGS) is currently recruiting participants for cholangiocarcinoma, multiple myeloma, …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Short Course Radiotherapy Followed by CAPOX and Carrilizumab and Bevacizumab or Cetuximab for the Initial Treatment of Unresectable Metastatic Rectal Cancer [Phase 2]
Phase 2 trial evaluating short-course radiotherapy followed by CAPOX and immunotherapy with camrelizumab plus either bevacizumab or cetuxima…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant Lesions
The trial sponsored by Amsterdam UMC (VUmc site) is currently recruiting to evaluate adaptive anastomosis techniques for anterior resection …
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Bowel Dysfunction After Low Rectal Resection. An Pilot Study Using Psyllium Husk In Rectal Cancer Patients. [NA]
Pilot clinical trial evaluating psyllium husk for bowel dysfunction after low rectal resection in rectal cancer patients, focusing on Low An…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Improving Diagnosis and Treatment for Patients With Rectal Cancer [NA]
This clinical trial update indicates that Imperial College London is conducting a study aimed at improving diagnosis and treatment for recta…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance [Phase 3]
Phase 3 clinical trial investigating intensified follow-up and surveillance after rectal cancer surgery to improve functional outcomes and q…