Recessive Dystrophic Epidermolysis Bullosa
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Characteristics of Patients With Recessive Dystrophic Epidermolysis Bullosa
A Stanford University-sponsored clinical trial aims to characterize patients with recessive dystrophic epidermolysis bullosa and is currentl…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Impact of COL7A1 Gene Therapy on SCC Recurrence in RDEB Skin [Phase 2]
Phase 2 clinical trial investigating COL7A1 gene therapy to reduce recurrence of squamous cell carcinoma in skin affected by recessive dystr…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa [Phase 1, Phase 2]
A clinical trial update indicates Phase 1/Phase 2 studies are investigating intravenous immunoglobulin–based therapy targeting collagen VII …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: GMEB-SASS: A Gene-Modified Skin Substitute for RDEB Treatment [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating GMEB-SASS, a gene-modified skin substitute, for treating recessive dystrophic epidermolysis bullosa, i…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa [Phase 3]
Phase 3 study evaluating KB803 versus matched placebo in Dystrophic Epidermolysis Bullosa is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)
A completed clinical trial sponsored by INSERM studied immune tolerance and wound healing in patients with Recessive Dystrophic Epidermolysi…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Rigosertib for RDEB-SCC [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating rigosertib for squamous cell carcinoma associated with recessive dystrophic epidermolysis bull…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa [Phase 1]
Phase 1 pilot study update for ELK-003 Eye Drops to treat ocular manifestations of epidermolysis bullosa, currently active/not recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients [NA]
A completed pilot trial evaluated Spincare Matrix, a temporary skin substitute, for wound healing in patients with Recessive Dystrophic Epid…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC [EARLY_Phase 1]
Early-phase 1 trial update reports completion of a study evaluating rigosertib in patients with Recessive Dystrophic Epidermolysis Bullosa-a…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated Patients [Phase 3]
A Phase 3b trial of EB-101 for recessive dystrophic epidermolysis bullosa (DEB) in new and previously EB-101 treated patients is active but …
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CLINICAL_TRIALS research · 2025-06-09Clinical Trial Update: Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART) [Phase 1, Phase 2]
A clinical trial update evaluating efgartigimod alfa (Vyvgart) to treat bullous diseases by targeting collagen VII antibodies in Epidermolys…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Pregabalin Treatment for RDEB Pain and Itch [Phase 3]
Phase 3 trial of pregabalin for pain and itch in recessive dystrophic epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: A Long-Term Extension Study for Participants Previously Treated With EB-101 for the Treatment of RDEB
A long-term extension study for participants previously treated with EB-101 for recessive dystrophic epidermolysis bullosa is enrolling by i…
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa [Phase 3]
Phase 3 study update for FCX-007 in Recessive Dystrophic Epidermolysis Bullosa. Results were posted in April 2024.
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CLINICAL_TRIALS trial_result · 2023-02-17Clinical Trial Update: Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of B-VEC for treating Dystrophic Epidermolysis Bullosa has completed with result…
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CLINICAL_TRIALS trial_result · 2022-12-05Clinical Trial Update: Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB) [Phase 3]
Phase 3 open-label trial of EB-101 for recessive dystrophic epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2022-11-21Clinical Trial Update: Extension Study to PTR-01-002 (A Study in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Patients Previously Treated With PTR-01) [Phase 2]
Phase 2 extension study update for PTR-01-002 in patients with recessive dystrophic epidermolysis bullosa (RDEB) who were previously treated…
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) [Phase 1, Phase 2]
Clinical trial update on intravenous gentamicin therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2022-10-07Clinical Trial Update: Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis Bullosa [Phase 1, Phase 2]
Phase 1/2 clinical trial of allogeneic ABCB5-positive stem cells for recessive dystrophic epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: A Study of PTR-01 in Recessive Dystrophic Epidermolysis Bullosa [Phase 2]
Phase 2 trial update for PTR-01 in recessive dystrophic epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa (RDEB) [Phase 1, Phase 2]
A Phase 1/2 study of FCX-007 for recessive dystrophic epidermolysis bullosa (RDEB) was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2021-03-09Clinical Trial Update: A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB) [Phase 1, Phase 2]
Phase 1/2 clinical trial of PTR-01 in adults with recessive dystrophic epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Safety and Effectiveness Study of Allogeneic Umbilical Cord Blood-derived Mesenchymal Stem Cell in Patients With RDEB [Phase 1, Phase 2]
Clinical trial updating safety and effectiveness of allogeneic umbilical cord blood-derived mesenchymal stem cells in patients with recessiv…
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: Safety Study and Preliminary Efficacy of Infusion Haploidentical Mesenchymal Stem Cells Derived From Bone Marrow for Treating Recessive Dystrophic Epidermolysis Bullosa [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing safety and preliminary efficacy of infusion haploidentical mesenchymal stem cells derived from bone marro…