Radiation-induced Xerostomia
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1 [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a circular RNA treatment for radiation-induced xerostomia and hyposalivation is currently recruiting, …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Sialendoscopy Versus Photobiomodulation in Prevention of Radiation Induced Xerostomia [NA]
A clinical trial is comparing sialendoscopy versus photobiomodulation to prevent radiation-induced xerostomia and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Pilot Study of Radiation-Induced Xerostomia Treatment With Allogeneic Mesenchymal Stromal Stem Cells [Phase 1]
A Phase 1 pilot study evaluating the safety and feasibility of using allogeneic mesenchymal stromal stem cells to treat radiation-induced xe…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction [Phase 1]
Phase 1 study evaluating the safety of a single administration of the AAV2hAQP1 gene therapy to the parotid gland in patients with irradiati…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Long-Term Follow-Up Study of AAV2hAQP1 for Radiation Induced Xerostomia
MeiraGTx is conducting a long-term follow-up study of the AAV2hAQP1 gene therapy for radiation-induced Xerostomia. The trial is listed as ac…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Screening of Biomarkers and Related Mechanisms for RIX
A recruiting clinical study evaluating biomarkers and related mechanisms underlying radiation-induced xerostomia (RIX).
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Management of Radiotherapy-related Xerostomia With Green Tea and Peppermint [NA]
Clinical trial evaluating green tea and peppermint for managing xerostomia caused by radiotherapy is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: The Efficacy of Hibiscus Sabdariffa in Xerostomia [NA]
A clinical trial is evaluating Hibiscus sabdariffa for radiation-induced xerostomia and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: Impact on Xerostomia for Nasopharyngeal Carcinoma Patients Treated With or Without Superficial Parotid Lobe-sparing Intensity-modulated Radiotherapy [Phase 2]
Phase 2 clinical trial evaluating the impact on xerostomia in nasopharyngeal carcinoma patients treated with or without superficial parotid …
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CLINICAL_TRIALS research · 2018-07-27Clinical Trial Update: Finger-prick Autologous Blood (FAB) for Use in Dry Mouth [NA]
Clinical trial update on Finger-prick Autologous Blood (FAB) for xerostomia, including radiation-induced xerostomia and xerostomia due to hy…
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Hyperbaric Oxygen for the Treatment of a Dry Mouth Which Occurred After Radiotherapy [Phase 2]
A Phase 2 trial of hyperbaric oxygen therapy for radiation-induced xerostomia has been terminated.
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: Efficacy of Novel Edible Gel-based Artificial Saliva in Cancer Patients [NA]
This is a completed clinical trial evaluating the efficacy of a novel edible gel-based artificial saliva for managing dry mouth in cancer pa…
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FDA label_change · 2013-04-26FDA Approved: SALAGEN — Supplemental Application (Advanz Pharma (US) Corp.)
The FDA approved a supplemental application for Salagen (pilocarpine hydrochloride) from Advanz Pharma (US) Corp., resulting in changes to t…
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CLINICAL_TRIALS trial_result · 2011-04-19Clinical Trial Update: Comparative Analysis of BioXtra on Xerostomia [Phase 2]
This update reports the completion of a Phase 2 trial evaluating BioXtra for treating radiation-induced xerostomia.