Pulmonary Hypertension
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Study of Ranolazine in the Treatment of Pulmonary Hypertension Associated With Diastolic Left Ventricular Dysfunction [Phase 4]
Phase 4 clinical trial of ranolazine for pulmonary hypertension associated with diastolic left ventricular dysfunction completed; results po…
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CLINICAL_TRIALS withdrawal · 2017-05-15Clinical Trial Update: Study of the Effects of Iron on Lung Blood Pressure at High Altitude [Phase 2]
This Clinical Trial Update indicates that the Phase 2 study of the effects of iron on lung blood pressure at high altitude has been withdraw…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Special Investigation For Long-Term Use Of Sildenafil (Regulatory Post Marketing Commitment Plan)
A post-marketing commitment study update evaluating long-term use of sildenafil for pulmonary hypertension has completed with results posted…
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CLINICAL_TRIALS withdrawal · 2017-04-11Clinical Trial Update: Safety and Tolerability of Inhaled Treprostinil in Adult PH Due to COPD [Phase 2]
A Phase 2 trial of inhaled treprostinil for adult pulmonary hypertension due to chronic obstructive pulmonary disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Insulin Resistance in Pulmonary Arterial Hypertension [Phase 2]
A Phase 2 trial investigating insulin resistance in pulmonary arterial hypertension was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting [Phase 2]
Phase 2 pilot study evaluating the harmful effects of stored blood in overweight individuals and the potential role of inhaled nitric oxide …
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CLINICAL_TRIALS research · 2017-03-23Clinical Trial Update: An Observational Study For Ambrisentan
This document reports a completed observational study of ambrisentan conducted by GlaxoSmithKline, focusing on pulmonary hypertension.
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Evaluation of Lung Doppler Signals in Pulmonary Hypertension
The clinical trial evaluating lung Doppler signals as a biomarker for pulmonary hypertension was terminated.
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension
A clinical trial assessed the safety and efficacy of treprostinil to facilitate liver transplantation in patients with portopulmonary hypert…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: A Proof of Concept Study of Electrical Discharge Produced Nitric Oxide for Inhalation [NA]
A completed proof-of-concept study evaluating inhaled nitric oxide produced by electrical discharge for potential use in pulmonary hypertens…
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CLINICAL_TRIALS research · 2017-01-24Clinical Trial Update: Latin American Pulmonary Hypertension Registry
An update on the Latin American Pulmonary Hypertension Registry (NCT02570737), a clinical trials registry sponsored by Asociación Latinoamer…
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CLINICAL_TRIALS withdrawal · 2017-01-11Clinical Trial Update: Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Right Heart Catheterization With Acute Vasodilator Testing
A clinical trial studying noninvasive cardiac output measurements in pulmonary hypertension patients undergoing right heart catheterization …
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CLINICAL_TRIALS research · 2017-01-04Clinical Trial Update: Pulmonary Hemodynamics in Patients With Severe Emphysema Pre and Post BLVR
This clinical trial update examines pulmonary hemodynamics in patients with severe emphysema before and after bronchoscopic lung volume redu…
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CLINICAL_TRIALS trial_result · 2016-12-30Clinical Trial Update: Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) [Phase 2]
Phase 2 clinical trial of inhaled prostaglandin E1 for hypoxemic respiratory failure in premature infants was terminated; results posted in …
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Endothelial Microparticles in Systemic Sclerosis Pulmonary Hypertension
This clinical trial update indicates the study examining endothelial microparticles in systemic sclerosis-associated pulmonary hypertension …
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD) [Phase 3]
A Phase 3 multicenter study evaluating inhaled iloprost for pulmonary hypertension following repair of congenital heart disease has complete…
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CLINICAL_TRIALS withdrawal · 2016-11-16Clinical Trial Update: Immunoadsorption in Patients With Pulmonary Hypertension [Phase 1, Phase 2]
A Phase 1/2 immunoadsorption clinical trial in patients with pulmonary hypertension has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Effect of Endothelin-1 Receptor Blockade on Circulating Endothelial Microparticles Levels in Patients With Pulmonary Hypertension
A completed clinical trial evaluated whether blockade of endothelin-1 receptors affects circulating endothelial microparticle levels in pati…
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Hemodynamic Effects of Stored Blood Transfusion in Intensive Care Patients [Phase 4]
A Phase 4 clinical trial evaluating the hemodynamic effects of stored blood transfusion in intensive care patients with pulmonary hypertensi…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: AZ, MZ, and the Pulmonary System Response to Hypoxia [Phase 4]
Phase 4 trial update examining how AZ and MZ influence the pulmonary system's response to hypoxia.
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Pulmonary Hypertension: Assessment of Cell Therapy [Phase 1]
This Phase 1 trial assessed a cell therapy for pulmonary hypertension and has completed, though no efficacy results are detailed in the snip…
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease [Phase 4]
Phase 4 trial update evaluating sildenafil for secondary pulmonary hypertension due to valvular heart disease. The study status is completed…
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: Safety and Efficacy Study of Bosentan in Progressive Pulmonary Sarcoidosis [Phase 2]
A Phase 2 safety and efficacy study of bosentan for progressive pulmonary sarcoidosis was terminated.
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery [Phase 3]
A Phase 3 confirmatory trial of IK-3001 in Japanese patients with peri-/postoperative pulmonary hypertension associated with cardiac surgery…
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide [Phase 2]
Phase 2 hospital-based trial evaluating inhaled nitric oxide for severe cardiopulmonary disease was terminated.