Pulmonary Arterial Hypertension
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: AIRDROP: Can we Improve Adherence to Inhaled Treatment for Pulmonary Arterial Hypertension? [NA]
The trial update indicates that AIRDROP is currently recruiting to study methods to improve adherence to inhaled therapy in pulmonary arteri…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Long-Term Outcomes of Selexipag in Schistosomiasis-Associated Pulmonary Arterial Hypertension
Clinical trial update on the long-term outcomes of selexipag for schistosomiasis-associated pulmonary arterial hypertension; the study statu…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Trial of "APL-9796'' in Adults With Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial of APL-9796 for adults with pulmonary arterial hypertension is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Clinical Trial of NS-863 in Participants With Pulmonary Arterial Hypertension (PAH) [Phase 2]
Phase 2 clinical trial update for NS-863 in pulmonary arterial hypertension, currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: An Expanded Access Study to Assess Treprostinil Palmitil Inhalation Powder (TPIP) for Participants With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
An expanded access study evaluating Treprostinil Palmitil Inhalation Powder (TPIP) for patients with pulmonary arterial hypertension and pul…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: 129 Xenon Imaging in Patients Treated With Sotatercept [Phase 2]
A Phase 2 clinical trial using Xenon imaging in patients treated with sotatercept for pulmonary hypertension is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Pulmonary Hypertension SOLAR [Phase 2]
Phase 2 clinical trial SOLAR investigating treatments for pulmonary hypertension associated with interstitial lung disease and COPD; the stu…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO) [NA]
This entry notes a clinical trial evaluating fetal endoscopic tracheal occlusion (FETO) for congenital diaphragmatic hernia with pulmonary h…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension [Phase 3]
Phase 3 open-label extension study of ralinepag in pulmonary arterial hypertension is ongoing, with enrollment by invitation to assess long-…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension [Phase 2]
Phase 2 clinical trial update for 2-HOBA in pulmonary arterial hypertension shows the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Patient-Reported Outcomes and Adherence After Transition From Inhaled Iloprost to Oral Selexipag in Pulmonary Arterial Hypertension
An upcoming clinical trial evaluating patient-reported outcomes and adherence after switching from inhaled iloprost to oral selexipag in pul…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: What is the Role of the Exposome in Pulmonary Hypertension
A clinical trial investigating how environmental exposures influence pulmonary arterial hypertension and chronic thromboembolic pulmonary hy…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Cognitive Alterations in Pulmonary Arterial Hypertension (PAH)
A clinical trial update about cognitive alterations in Pulmonary Arterial Hypertension. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Riociguat in Triple Therapy for Pulmonary Arterial Hypertension in Real-World Practice
A clinical trial update evaluating riociguat as part of triple therapy for pulmonary arterial hypertension in real-world practice; the study…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH) [Phase 3]
Clinical trial update on Inhibikase Therapeutics' adaptive IKT-001 program for pulmonary arterial hypertension; the Phase 3 study is current…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension [NA]
This clinical trial update describes a study evaluating exercise as an adjunct to standard medical therapy in patients newly diagnosed with …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Impact of Sotatercept on Pulmonary Artery and Right Ventricle Remodeling Imaging Assessed With 68Ga-FAPI PET/CT in Patients With PAH [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating sotatercept in pulmonary arterial hypertension, using 68Ga-FAPI PET/CT imaging to assess remodeling of…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: PET Image in PAH Patients [EARLY_Phase 1]
An early-phase 1 study assessing PET imaging in patients with Pulmonary Arterial Hypertension is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Genetic Hallmarks of Patients With Congenital Portosystemic Shunts and Portopulmonary Hypertension
A clinical trial study investigating the genetic hallmarks of patients with congenital portosystemic shunts and portopulmonary hypertension;…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of the investigational drug L608 in healthy adults; the trial lists Pulm…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia
This is a prospective longitudinal observational cohort study of pregnant women living at high altitude in Bolivia, sponsored by Massachuset…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension [Phase 2]
A Phase 2 trial update indicates empagliflozin is being studied to improve right ventricular function in pulmonary arterial hypertension and…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: SIRIUS - Initial Combination Therapy With an Endothelin Receptor Antagonist, a Phosphodiesterase-5 Inhibitor and Sotatercept in Patients With Newly Diagnosed Pulmonary Arterial Hypertension [Phase 2]
A Phase 2 clinical trial (SIRIUS) will evaluate an initial triple therapy—an endothelin receptor antagonist, a phosphodiesterase-5 inhibitor…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Circulating Activin-A and FSTL3 in Precapillary Pulmonary Hypertension [NA]
A clinical trial is investigating circulating activin-A and FSTL3 in precapillary pulmonary hypertension. The study is currently active but …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular Comorbidities [Phase 3]
Phase 3 clinical trial entry comparing initial dual oral therapy versus monotherapy for pulmonary arterial hypertension with cardiovascular …