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CLINICAL_TRIALS research · 2025-12-05

Clinical Trial Update: SIRIUS - Initial Combination Therapy With an Endothelin Receptor Antagonist, a Phosphodiesterase-5 Inhibitor and Sotatercept in Patients With Newly Diagnosed Pulmonary Arterial Hypertension [Phase 2]

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Summary

A Phase 2 clinical trial (SIRIUS) will evaluate an initial triple therapy—an endothelin receptor antagonist, a phosphodiesterase-5 inhibitor, and sotatercept—fo…

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Diseases / indications

Drugs mentioned

  • Endothelin receptor antagonist
  • Phosphodiesterase-5 inhibitor
  • Sotatercept (sotatercept)

Snippet

Sponsor: Philipps University Marburg | Conditions: Pulmonary Arterial Hypertension (PAH) | Phase 2 | Status: NOT_YET_RECRUITING